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Background: Macrosomia is a term applied to newborns with a birth weight of >4000g.
This condition leads to several maternal and fetal complications including
maternal traumas as well as newborn injury. This study was designed to evaluate
the risk factors of macrosomia among Iranian women.
Methods: This cross-sectional study performed between July 2001
and July 2002, included 2000
term deliveries involving newborns with birth weights of >2500g.
The records of 77 mothers of live born
infants weighing >4000g
were compared to those of the control group (231
women). Stillborn and neonates who were <2500g
were excluded from the study.
Results: Among the 2000 deliveries performed
in Imam Hospital, 77(3.8%)
of the newborns weighed >4000g and 12(0.6%)
weighed >4500g. The mean age of the
mothers, maternal BMI, history of diabetes
mellitus, multiparity, fetal sex and underling maternal disease were found to
be associated with increase risk of fetal macrosomia. There was no significant
relationship between prolonged gestation, weight gain more than 16kg
during pregnancy and past history of macrosomic delivery and macrosomia.
Conclusions: It is possible to prevent macrosomia by weight and diabetes control before the decision
to become pregnant. To prevent pregnancy among multipara mothers aged >35
years old, highly protective contraceptive methods should be used. Furthermore,
if a mother is diagnosed with a macrosomic fetus by sonography or other imaging
methods, more care should be taken during the delivery to decrease the risk of
fetal injury, such as asphyxia and brachial plexus palsy.
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