Scolicidal effect of alcoholic, aqueous and total alkaloids of Peganum Harmala L. (Syrian Rue) against hydatid cysts protoscolices

Mahdavi M,; Masood J,

Volume 60, Issue 3 (14 2002) Tehran Univ Med J 2002, 60(3): 215-226 | Back to browse issues page

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Mahdavi M, Masood J. Scolicidal effect of alcoholic, aqueous and total alkaloids of Peganum Harmala L. (Syrian Rue) against hydatid cysts protoscolices. Tehran Univ Med J 2002; 60 (3) :215-226
URL: http://tumj.tums.ac.ir/article-1-1255-en.html

Scolicidal effect of alcoholic, aqueous and total alkaloids of Peganum Harmala L. (Syrian Rue) against hydatid cysts protoscolices

Mahdavi M

, Masood J

Abstract: (14400 Views)

Introduction: Alcoholic and aqueous extracts and total alkaloids of the seed of (Syrian rue) peganum harmala L. as scolicidal compound against Hydatid cyst protoscolices were assessed in this study.

Methods and Materials: This study was carried out both invitro and by inoculating inside the intact cysts in the shaking bath and dry incubator at 37°c. Different concentration of suspensions were tested in different exposure times. Mortality of protoscolices was determined by their loss of mortality, ability to take vital stains and inactivity of flame cells.

Results: The results indicated that alcoholic extract had scolicidal effect against protoscolices total alkaloids had stronger action and rapid effect on protoscolices.