Showing 1 results for D Jamali Zavareii. M
D Jamali Zavareii. M, Jarrahi. Mr,
Volume 64, Issue 11 (7 2006)
Abstract
Background: Germ cell aplasia (G.C.A) is one of the most important testicular
causes of infertility and azospermia.In this condition the seminiferous tubules
are only lined by a single layer of sertoli cell. In some cases, there is focal area
with spermatogenic activity.
Methods: We studied infertile men with G.C.A referred to Jahade Daneshgahi
of Iran during 1381-82, retrospectively. All the cases had more than one
biopsy of one testis.
Results: In 11.6٪ of 320 cases, comparison of multiple biopsy sites of a testis
revealed: when one site showed G.C.A, another site revealed areas with
spermatogenic activity. Considering the cases who showed germ cells in both
sites, 15.3٪ of cases multiple biopsy sites appeared to have focal
spermatogenesis, better maturation of germ cells or higher scoring area for
urologic operation.
Conclusion: According to new techniques in treatment of infertility with ICSI
(intra cytoplasmic sperm injection) in which fertility is possible with one
spermatozoa or even spermatid (after recovery), biopsy of multiple sites
instead of only one site is highly recommended in azospermic patient.
