Marjan Sabbaghian, Tahereh Modarresi, Hani Hosseinifar, Ali Daliri Hampa, Leila Karimian, Firoozeh Ghaffari, Jalil Hosseini, Mohammad Ali Sadighi Gilani,
Volume 71, Issue 8 (November 2013)
Abstract
Background: Intrauterine insemination (IUI) is one the most common methods in infertility treatment, but its efficiency in infertile couples with male factor is controversial. This study is a retrospective study about correlation between semen parameters and male and female age with successful rate of IUI in patients attending to Royan Institute.
Methods: A total of 998 consecutive couples in a period of 6 months undergoing IUI were included. They were classified into two groups: couples with successful and unsuccessful pregnancy. Main outcome was clinical pregnancy. Data about male and female ages and semen analysis including concentration, total sperm motility, class A motility, class B motility, class A+B motility and normal morphology was extracted from patients’ records. Semen samples were collected by masturbation or coitus after 2 to 7 days of abstinence. Their female partners were reported to have no chronic medi-cal conditions and have normal menstrual cycles.
Results: One hundred and fifty seven of total 998 cycles (15.7%) achieved pregnancy. The average of female age in successful and unsuccessful group was 28.95±4.19 and 30.00±4.56 years, respectively. Mean of male age was 33.97±4.85 years in successful group and 34.44±4.62 years in unsuccessful group. In successful and unsuccessful groups, average of sperm concentration was 53.62±38.45 and 46.26±26.59 (million sperm/ml), normal morphology of sperm was 8.98±4.31 (%) and 8.68±4.81 (%), sperm total motility was 47.24±18.92 (%) and 43.70±20.22 (%) and total motile sperm count was 80.10±63.61 million and 78.57±68.22 million, respectively.
Conclusion: There was no significant difference in mean of females’ age and males’ age between successful and unsuccessful groups (P<0.05). In addition, there was no significant difference in semen parameters including concentration, total sperm motility, class A motility, class B motility, class A+B motility and normal morphology between two groups. It was shown that common semen analysis and male and female ages cannot predict IUI outcome.
Salman Daliri , Khairollah Asadollahi , Nazila Rahimi, Kourosh Sayehmiri ,
Volume 75, Issue 9 (December 2017)
Abstract
Background: The deficiency of enzyme glucose-6-phosphate dehydrogenase (G6PD) is among the most common genetic diseases in human. The deficiency of G6PD enzyme is one of the most common encountered enzymes, affecting about 400 million people and causing a wide range of undesirable clinical complications worldwide. The performed studies have reported a variety of statements about the relationship between malaria and survival of people with defect, but these kinds of studies are limited in Iran. This study aimed to estimate the incidence of G6PD deficiency among newborns in malarious areas of Fars province.
Methods: The present study was conducted ecologically and descriptively-analytically on 59745 neonates with G6PD deficiency in Fars province, Iran from April 2011 to March 2015. To determine the defect, a point fluorescence test and Kimia commercial kit (KimiaPajoohan Co., Tehran, Iran) were used. To determine the areas with malaria, factors associated with malaria-causing cells in Fars province, including the presence of carriers, the presence of malaria, the incidence of new malaria and the presence of malaria activated sites were studied. The incidence of defect was calculated using the statistical method of estimating the annual incidence rate. ArcGIS software, version 10.3 (ESRI, Redlands, CA, USA) was used to provide geographic mappings and distribution patterns in malarious areas.
Results: The total incidence of G6PD deficiency in newborns was estimated as 15.58 per 100 live births, including 16.25 for boys and 14.85 for girls. The incidence of this defect in malaria-prone areas was higher than other areas. As a region was more malaria-prone, the incidence of G6PD deficiency increased too, which was statistically significant (P= 0.039).
Conclusion: Based on the findings of this study, Fars province is among areas with high incidence of G6PD deficiency. The incidence of G6PD deficiency in malaria-prone areas of Fars province, Iran, is higher than other regions, which indicates better survival of patients against malaria in the past.
Mina Khanhoseini, Hossein Sheybani, Salman Daliri, Zahra Hadadi, Hengameh Khosravani,
Volume 79, Issue 3 (june 2021)
Abstract
Background: Acute coronary syndrome (ACS) is one of the causes of disability and death. Levels of Uric acid, blood glucose, and dyslipidemia are the risk factors for the disease, but their role in electrocardiographic changes has not been studied. Based on this, this study aimed to investigate the relationship between some demographic and clinical characteristics with electrocardiographic changes.
Methods: This cross-sectional study was performed on 484 patients with Acute Coronary Syndrome admitted to Shahroud Imam Hossein Hospital from the beginning of January to the end of June 2018. In this study, the relationship between demographic, clinical and laboratory variables in patients with the acute coronary syndrome with STE, STD, Dynamic changes and inverted T waves were investigated. The required information was extracted from the Patients' records using the researcher-made checklist. Statistical analysis of data was conducted by using descriptive tests for estimating mean and frequency and statistical-analytical tests including chi-square and ANOVA were performed by SPSS software version 22.
Results: The results show that the proportion of STD deviations in women with ACS was 12.6% higher than in men, but the proportion of STE and Dynamic changes in men was 10.4% and 12.2% higher than women, respectively. The proportion of STD, STE, inverted T and Dynamic changes in people with hyperlipidemia was 67.8%, 77.6%, 64.7% and 75.8%, respectively. The proportion of STD, STE, inverted T and Dynamic changes in patients with hypertension were 0.12%, 5.1%, 11.2%, and 19.1%, respectively that there was a difference with patients without high blood pressure. Between addiction, fasting blood sugar and LDL with STD; Between History of heart disease, history of angiography, hypertension, creatinine and WBC with STE; and between creatinine and fasting blood sugar statistically significant differences were observed.
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Conclusion: There were significant correlations between electrocardiogram changes, gender, addiction, hypertension, creatinine, LDL level, fasting glucose and white blood cell count.
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Salman Daliri, Mohammad Khanbeigi, Reza Heidary Moghadam , Parisa Asadollahi, Khairollah Asadollahi,
Volume 79, Issue 8 (November 2021)
Abstract
Background: Pulse pressure has recently been considered as a predictor of coronary heart disease. The difference between systolic and diastolic blood pressure is called pulse pressure. Various factors including increased age, vascular stiffness, stenosis, and hypertension are associated with pulse pressure. The present study, therefore, aimed to investigate the relationship between some cardiovascular function indicators such as vascular stenosis, blood pressure and cardiac output with pulse pressure as a predictor of cardiovascular diseases.
Methods: This case-control study was performed on 544 patients who were referred to Imam Ali Hospital in Kermanshah, Iran, from March 2015 to February 2016. In this study, according to the angiographic findings, individuals with artery stenosis were considered as the case group (n=272) and those without artery stenosis were considered as the control group (n=272). Statistical analysis was performed using descriptive statistics, Chi-square and odds ratio estimation by SPSS22 software.
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Results: According to the findings of this study, ages over 50 (OR: 3.3, 95% CI: 2.1-5.2), high systolic blood pressure (OR: 8, 95% CI: 4.3-15.2), high diastolic blood pressure (OR: 4.9, 95% CI: 2.0-11.7), cardiac output less than 50% (OR: 1.8%, 95% CI: 1.3-2.7) and vascular stenosis (OR: 3.5, 95% CI: 2.4-5.1) were associated with high pulse pressure. The male gender had a preventive role in increasing of pulse pressure (OR: 0.7, 95% CI: 0.5-0.9). A significant relationship was demonstrated between systolic blood pressure and pulse pressure (P<0.0001).
Conclusion: Based on the findings of the present study, the chances of having high pulse pressure are high among individuals over 50 years of age, female gender, those with elevated systolic and diastolic blood pressure, and individuals with high coronary artery stenosis. This chance is associated with decreased cardiac output and coronary stenosis. Increased pulse pressure is a predictive indicator of cardiovascular disease and it is recommended that pulse pressure measurements of all referrals, especially those who are being referred to cardiology clinics, are taken into account by medical professionals to prevent adverse clinical outcomes.
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