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A randomized, prospective study of adjunctive Ampicillin in preterm labor
A Tehranian , P Hasel ,
Volume 57, Issue 4 (9 1999)
Abstract
Acute amniotic fluid infection has emerged as a possible cause of many heretofore unexplained preterm births. Our purpose was to determine the effect of ampicillin in the prolongation of pregnancies receiving tocolysis for preterm labor. A blinded, placebo-controlled, randomized trial was conducted to study ampicillin in women hospitalized for preterm labor between 24 and 37 weeks' gestation. A total of 60 patients with intact membranes and without chorioamnionitis who were receiving magnesium sulfate were screened. Thirty women with preterm labor received ampicillin, and 30 received placebos. The primary end point was prolongation of gestation. There was no difference in age of delivery (37.6±9.7 days vs 36.08±3.9 days, P=0.085) and no difference in retardation of delivery (4.7±3.1 vs 4.1±2.1, P=0.39). The mean degree of preterm delivery were 0.62±1.93 and 1.8±3.3 weeks in ampicillin and placebo groups, respectively (not significant, P>0.1). Conclusions: Ampicillin had no effect on interval to delivery or duration of pregnancy in women treated for preterm labor. So rotine clinical use of ampicillin during tocolysis should not be recommended.
A convenient and fast method for assessing the image quality of hepatic triphasic CT scan
Seyed Hamed Jafari, Hajar Zahedi Mehr , Banafsheh Zeinali-Rafsanjani , Sara Haseli, Mahdi Saeedi-Moghadam ,
Volume 80, Issue 6 (September 2022)
Abstract
Background: The image quality is paramount in interpreting the hepatic dynamic CT scan. A poor quality image results in repeating the procedure, which is very time-consuming for the patient and staff, and besides, it is not cost-efficient. This study intended to determine the correlation between image quality and the Hounsfield unit (HU) of the liver and its vessels in the arterial and venous phase to define the acceptable range of HUs for hepatic CT images.
Methods: The image quality of 146 dynamic CT scans was assessed by qualitative and quantitative methods at Namazi Hospital of Shiraz University of Medical Sciences from September 2019 to August 2021. Two radiologists performed the qualitative evaluation. They categorized the image qualities into three groups; poor, acceptable, and high quality. For quantitative assessment of image quality, the Hounsfield unit of the aorta, hepatic vein, main portal vein, right anterior, right posterior, and left lateral lobe of the liver were evaluated in both arterial and venous phases.
Results: According to the results of the qualitative evaluation of image quality, 59.6%, 17.8%, and 22.6% of triphasic CT scans had good, acceptable, and poor quality, respectively. There was a significant relationship between image quality and Hounsfield units of all ROIs in the arterial phase (P<0.005). Also, a significant relationship was observed between the Hounsfield units of the portal vein right on the anterior and posterior segments of the liver (P<0.03) in the venous phase.
Conclusion: In a high quality triphasic CT scan, the Hounsfield unit of different parts in the arterial phase should be as follows: aorta 310±78, portal vein 150±40, hepatic vein 44±7, right posterior and anterior and left lateral segments of liver 77±11, 77±7 and 78±12. Hounsfield units of the portal vein, hepatic vein, and right posterior and anterior segments of the liver in the venous phase should be 155±27, 167±30, 111±19, and 112±16, respectively.

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