Showing 5 results for Mahdavi M
Mahdavi M, Masood J,
Volume 60, Issue 3 (14 2002)
Abstract
Introduction: Alcoholic and aqueous extracts and total alkaloids of the seed of (Syrian rue) peganum harmala L. as scolicidal compound against Hydatid cyst protoscolices were assessed in this study.
Methods and Materials: This study was carried out both invitro and by inoculating inside the intact cysts in the shaking bath and dry incubator at 37°c. Different concentration of suspensions were tested in different exposure times. Mortality of protoscolices was determined by their loss of mortality, ability to take vital stains and inactivity of flame cells.
Results: The results indicated that alcoholic extract had scolicidal effect against protoscolices total alkaloids had stronger action and rapid effect on protoscolices.
Mahdavi Mazdeh M, Moradiance V, Lesan Pezeshki M, Jahan Zad I,
Volume 61, Issue 3 (14 2003)
Abstract
LP(a) level in uremic patients is high. It has recently considered that the effect of androgens on lipids vary widely. The aim of this study was to determine the effect of nandrolone decanoate on lipid profile in chronic hemodialysis patients.
Materials and Methods: thirty six stable male patients over 40 years who were under maintenance hemodialysis were randomized to receive nandrolone decanoate , 100 mg weekly for six month, by intramuscular injection on nondialysis day (Group A, N=18) or B complex (Group B, N=18). Between September 2001 and 2002, male hemodialysis patients more than 40 years old without history of high prostatic specific antigen (PAS) or sensitization to drug were started on treatment with androgen therapy. The evolution in the liquid profile was prospectively assessed immediately before the first dose of nandrolone decanoate (basal values) and at 2, 4 and 6 month of therapy. The evolution of lipids after withdrawal of androgens at 2 month after the last dose was also studied. The patients underwent hemodialysis 3 to 4 hours three times a week. The dialysis schedule was not modified during the period of study.
Results: Mean decrease of LP(a) level in group A was significantly lower then group B in second month (p<0.05). Surprisingly HP level decreased also in second month. Other lipid parameters did not show significant changes.
Conclusion: In this study we observed that nandrolone decanoate affects on LP(a) leveK but the changes of it did not correlate with those of hemoglobin or other lipid parameters< suggesting that the underlying mechanisms are unrelated. Our finding might be affected by low dose of the drug. Further studies with higher doses will be requied to clarify the beneficial or adverse effects of this type of therapy.
Rassulinejad M, Hossami Roodsari H, Mahdavi Mazdeh M, Hajiabdolbaghi M, Ahmadi F L,
Volume 61, Issue 6 (15 2003)
Abstract
Renal transplantation is ideal treatment of chronic renal failure. Pulmonary infection is a common and serious post transplant infection requiring hospitalization and is associated with high mortality. Increased susceptibility to infection is due to a decrease in the patients' immunological response caused by immunosuppression through drug administration, and by other influences.
Materials and Methods: This study was case series and prospective, from July 2001 to July 2002 in Imam Khomeini hospital of Tehran.
Results: 164 renal transplant recipients were studied, 14 patients (8.5%) had pulmonary infection, 11 of them (78.6%) were female and 3 (21.4%) were male. The mean age of them was 42.6 years. The patients were followed up for 9 to 12 months. All patients were on triple immunosuppressive regimens. The interval between transplantation and the appearance of pneumonia was 2 months to 10 years. The time of beginning infection in 3 cases (21.4%) was between 1 to 6 months post transplantation, 11 cases (78.6%) were occurred beyond 6 months after transplantation. In 7 cases (50%), pulmonary infection was occurred during first year after transplantation. None of the 14 patients developed pulmonary infection in first month after transplantation. BAL were used in 6 cases (42.8%) of pulmonary infection, and organism were detected in 5 of them (83.3%). The most common clinical feature was fever. Six cases were due to mycobacterium tuberculosis (42.9%), this organism was the most common ethiology of pneumonia. In this study tuberculosis was seen in 3.6% of renal transplant recipients. One patient had pulmonary mucormycosis. All patients with pulmonary TB were cured, and other cases with unknown case, were cured with empirical treatment.
Conclusion: Our finding indicate the invasive diagnostic procedures are required in order to earlier and reliable diagnosis and then better outcome of transplantation.
Shoja Mr, Mahdavi M, Manaviat Mr, Besharati M.r,
Volume 64, Issue 11 (7 2006)
Abstract
Background: Diabetes Mellitus is the most common endocrinologic disease in human and retinopathy is one of the most common complications. Etiology of this complication is yet unknown but one of the factors that can be effective on its production or progression is serum lipid. We aim to study the relationship between different degrees of diabetic retinopathy and serum lipids levels.
Methods: An observational cross-sectional study designed to study over 37 patients with diabetes mellitus type one and 157 patients with diabetes mellitus type two. Former was selected as sensus and latter was selected randomly from diabetic patients attending the diabetes clinic in Yazd during 2002. Inclusion criteria was duration of diabetes at least seven years from diagnosis. Statistical analysis performed by SPSS package edition 11 and wit statistical tests as Chi square, Fisher Exact and ANOVA.
Results: Among 194 cases, 74 cases were males and 120 females. 90 cases (46.4%) have normal total serum cholesterol and 104 (53.6%) hypercholestrolemia. In case of triglyceride 94 cases (48.4%) have normal serum triglyceride and 100 (51.6%) hypertriglyceridemia. Distribution of different degrees of diabetic retinopathy was statistically significant due to cholesterol and triglycerides (P-Value<0.05). In different groups of sex, diabetic retinopathy was more prevalent if there was hypertriglyceridemia or hypercholesterolemia. This was correct about different groups of age and type of diabetes. This means that in different groups of age and type of diabetes, diabetic retinopathy was more prevalent if there was hypertriglyceridemia or hypercholesterolemia.
Conclusion: Prevalence of diabetic retinopathy is higher in cases with hypertriglyceridemia or hypercholesterolemia than cases with normal serum triglyceride or cholesterole.
Mahdavi M E, Peyvandi A A,
Volume 65, Issue 3 (2 2007)
Abstract
Background: Cortical Evoked Response Audiometry (CERA) refers to prediction of behavioral pure-tone thresholds (500-4000 Hz) obtained by recording the N1-P2 complex of auditory long latency responses. CERA is the preferred method for frequency–specific estimation of audiogram in conscious adults and older children. CERA has an increased accuracy of determination of the hearing thresholds of alert patients with elevated hearing thresholds with sensory hearing loss however few publications report studies regarding the use of CERA for estimating normal hearing thresholds. The purpose of this research was to further study the accuracy of CERA in predicting hearing thresholds when there is no hearing loss.
Methods: Behavioral hearing thresholds of 40 alert normal hearing young adult male (40 ears) screened at 20 dB HL in 500-8000Hz, predicted by recording N1-P2 complex of auditory evoked long latency responses to 10-30-10 ms tone bursts. After CERA, pure tone audiometry performed by other audiologist. All judgments about presence of responses performed visually. Stimulus rate variation and temporary interruption of stimulus presentation was used for preventing amplitude reduction of the responses. 200-250 responses were averaged near threshold.
Results: In 95% of the hearing threshold predictions, N1-P2 thresholds were within 0-15 dB SL of true hearing thresholds. In the other 5%, the difference between the CERA threshold and true hearing threshold was 20-25 dB. The mean threshold obtained for tone bursts of 0.5, 1, 2 and 4 kHz were 12.6 ± 4.5, 10.9 ± 5.8, 10.8 ± 6.5 and 11.2 ± 4.1 dB, respectively, above the mean behavioral hearing thresholds for air-conducted pure tone stimuli.
Conclusion: On average, CERA has a relatively high accuracy for the prediction of normal hearing sensitivity, comparable to that of previous studies performed on CERA in hearing-impaired populations.
