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Showing 3 results for Masoudi
Relationship of fatty acids content of LDL particles with their electrical charges in patients with coronary artery disease
Rouhangiz Babakhanianzadeh, Nahid Masoudian , Amirnader Emami Razavi, Gholam Basati ,
Volume 73, Issue 7 (October 2015)
Abstract

Background: Low density lipoprotein (LDL) particles have shown to be heterogeneous structures with distinctive electrical charges. Alteration in the fatty acids content of the LDL particles is known to affect their structural features, electrical charges, and ultimately physiologic properties and, in this way, may play a role in the pathology of coronary artery disease (CAD). On the basis of evidences, in the present study, the relationship of fatty acids content of LDL particles and their electrical charge was assessed in patients with CAD in comparison with control subjects. Methods: In the current case- control study, from subjects who referred to the Mostafa Khomeini Hospital in Ilam during a time period from December 2013 to October 2014, 40 CAD patients and 40 control subjects were selected based on the clinical and angiographic parameters. The fatty acids content and electrical charges of LDL particles were measured by using a gas chromatography system, equipped with a flame ionization detector GC-FID, Acme 6000 M (Young Lin Co., Korea) as well as a Zetasizer (Malvern Instruments Ltd., UK), respectively. Results: In the present study, CAD patients and control subjects were matched for age, sex, and body mass index (BMI). The electrical charge amounts of LDL particles in the patients group was significantly lower than those in the control subjects (P= 0.0001). There was an inverse correlation between the electrical charge amounts of the LDL particles and the saturated fatty acids as well as linoleic acid contents of them in CAD patients group. However, we found a direct correlation between the unsaturated fatty acids (monounsaturated fatty acids and some of the polyunsaturated ones) content of the LDL particles and their electrical charge amounts (P= 0.02). Conclusion: Results of the present study demonstrated that the increased saturated fatty acids as well as the linoleic acid contents of the LDL particles are associated with decreased electrical charge amounts of these particles and this situation may engage in pathogenesis of CAD.


Comparison of dexmedetomidine versus midazolam on hemodynamic parameters, bleeding, satisfaction of surgeons and patients who Underwent laminectomy surgery by spinal anesthesia
Behzad Nazemroaya, Mehrdad Masoudifar , Motahare Rajabi Moghadam ,
Volume 79, Issue 5 (August 2021)
Abstract
Background: One of the most empirical subjects particularly in substantial operations for example in surgeries involving the vertebral column, are the implication of sedatives in a manner which would create the least complications such as changes in the hemodynamic parameters. Two such drugs that are widely used in this capacity in clinical settings are midazolam and dexmedetomidine. Hemodynamic stability is particularly important in surgical operations, especially during spinal surgery. One of the ways to prevent hemodynamic changes during surgery is the use of drugs such as midazolam and dexmedetomidine.
Methods: This double-blind randomized clinical trial recruited 105 patients undergoing laminectomy spinal surgery under spinal anesthesia at Al-Zahra Hospital, Isfahan between 21 April 2019 till 1 September 2019. Patients were randomly divided into 3 groups: First was the midazolam group, second the dexmedetomidine group and the third was the control group. Data were presented as mean±standard deviation and percentages. In order for the evaluation of differences to be performed between all groups, an evaluation using the one-way analysis of variance was utilized. Statistical analysis was done by means of the SPSS software version 23 (IBM Corporation, Armonk, New York, USA). The P-value which was accepted as significant was P less than 0.05. (P<0.05)
Results: There differences in age and gender were not statistically significant among the studied groups (p>0.05). Results from the ANOVA test showed that the effects when taking into consideration time (P<0.001) and group (P<0.001) were statistically significant on Mean of Arterial Pressure, Systole Blood Pressure and Diastole Blood Pressure. However, Heart Rate and oxygen saturation (SPO2) were not significantly different inter-group as well as intra-group over time (before, during, and after the operation) (P=0.12).  Furthermore, the mean of the hemorrhage amount and duration of recovery stay had significant differences over time between all three groups (P<0.05).
Conclusion: The incidence of complications during surgery in the dexmedetomidine group was less than the midazolam group. Additionally, the frequency of complications in the subjects given midazolam was higher than the dexmedetomidine group during recovery.

Study of stress and anxiety levels before embryo transfer in women candidates for intracytoplasmic sperm injection
Saeideh Baghaei Barjini , Mozhgan Masoudi , Soheila Pirdadeh Beiranvand , Ashraf Moieni , Soodabeh Zare,
Volume 82, Issue 12 (March 2025)
Abstract
Background: Intracytoplasmic sperm injection (ICSI) is one of the infertility treatments that may lead to various levels of stress and anxiety in women at different stages. Multiple factors may contribute to these psychological disorders. This study aimed to assess the levels of stress, anxiety, and depression before embryo transfer in women undergoing ICSI.
Methods: This cross-sectional analytical study was conducted from July to October 2024 on 70 women candidates for ICSI at Arash Women's Hospital in Tehran, prior to embryo transfer. Participants were selected through convenience sampling. Inclusion criteria included at least three years of infertility, no background in psychology or attendance in counseling sessions, no major physical or mental illnesses, and no severe stressful events in the past six months (such as the death of first-degree relatives or major accidents). Participants could withdraw from the study at any time. The DASS-21 (Depression, Anxiety, Stress Scale) was used to assess stress and anxiety levels. Based on the DASS-21, stress scores of 0-14 were considered normal or mild, 15-18 mild, 19-25 moderate, 26-32 severe, and ≥33 very severe. For anxiety, scores of 0-7 were considered normal or mild, 8-9 mild, 10-14 moderate, 15-19 severe, and ≥20 very severe. The validity of the tool was confirmed by Antony and validated in Iran by Sahebi.
Results: Among the 70 participants, 92.8% experienced stress and anxiety. The mean stress score was 20.77±4.87, and the mean anxiety score was 11.70±4.23, indicating moderate levels. Women over 42 years old had significantly lower stress scores compared to others (P<0.001). Conversely, women under 30 showed significantly higher anxiety scores (P<0.01). No significant associations were found between stress/anxiety and other demographic or infertility-related factors (P>0.05).
Conclusion: The findings indicate that women undergoing embryo transfer in ICSI procedures commonly experience stress and anxiety. Therefore, appropriate psychological interventions are recommended to support this group during treatment.

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