Tehran University Medical Journal

Background: CNS infection can be focal or generalized. Meningitis, besides other etiologies, can occur after a viral infection or viral vaccine. Although meningitis can occur in at any age but it is more common in children less than five years old. Aseptic meningitis and meningoencephalitis are two of the most common complications of mumps (wild type or vaccine). As a result of their serious complication, we decided to obtain more information about clinical manifestations and laboratory findings after the injection of the Hoshino MMR vaccine in a group of children in an Iranian referral hospital.
Methods: In this cross-sectional study, performed from March 2013 to February 2015 on 73 children with meningochemical symptoms of meningitis, children who have been diagnosed with aseptic meningitis followed by an MMR vaccine in an infectious ward or emergency department of the Children’s Medical Center were enrolled in the study and their information was recorded from their files. A questionnaire was provided for children with diagnostic criteria of aseptic meningitis and their data were collected.

Background: Type 1 diabetes mellitus, with its increasing prevalence in the pediatric population, has a significant impact on the mental health, quality of life, and lifestyle of patients.. The onset of the disease in childhood and its association with the child during school and adolescence, and during the growth and development process, has numerous effects on the growth process and mental experiences of patients.
Methods: This cross-sectional study was conducted in Children, s Medical Center from  march 2022 to February 2023 on 183 patients with type 1 diabetes aged 9 to 18 years. The duration of the disease ranged from 1 year to 15 years. 44% of the populations were girls and 56% were boys. 77% were under 13 years of age and the rest were over 13 years of age. Information was completed by parents in the Achenbach electronic questionnaire (112 questions). Then, based on the standard defined for the questionnaire, the scores were classified into clinical, borderline, and normal categories.
Results: No significant differences were observed between the two sexes in terms of the incidence of various disorders. However, significant differences in the incidence of externalizing problems have been reported at different ages and different disease durations. Analysis of the mean T-scores of the studied patients showed that there were significant differences between patients older than 13 years younger than 13 years in terms of externalizing problems, anxiety/depressive disorders, attention deficit/hyperactivity disorders, law-breaking behavior, internalizing problems, and general problems.  a significant relationship was observed between the study population and the duration of the illness in terms of aggressive problems, law-breaking problems, and externalizing disorders.
 Average scores in externalizing disorders, affective/depressive disorders, law-breaking behavior, internalizing problems, and general problems were significantly related to different ages.
Conclusion: The results of this study show that as patients aging and more than 5 years  since the onset of diabetes, the risk of developing psychiatric disorders increases. As a result, routine psychiatric screening is recommended for these children.