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Moradi F, Nabaei B, Yeganeh B,
Volume 58, Issue 4 (8 2000)
Abstract

The problem of AIDS had not been recognized up to 1981 and in 1984 it was found that HIV virus is factor of this disease. For the time beings AIDS/HIV infection has chanched to a pandemic and cases affected to it are now reported from all over the world. In our country the first case was reported in 1987. Regarding the importance of disease and recognition of its prevention and transmission routes, based on disease epidemiology in country, this survey was conducted. This study was performed in 1999-2000 and is retrospective descriptive study. The main purpose of study is epidemiology of AIDS in Iran from beginning until now. Total information of cases of AIDS/HIV from beginning in Iran and all performed activities were obtained from ministry of health center for disease control-AIDS Dept. 95 files existing in the archives of Imam Khomeini hospital related to AIDS were also studied. 1953 cases of HIV+ have been reported until March of year 2000. At the same time 250 cases of AIDS have been reported which 215 of them died. Among transmission routes, in AIDS disease the most common way of transmission was transfusion of infected blood or its components but in HIV+ case the most one was drug injection. With respect to age, the higher and lower rate of affected people were in 30-39 and 0-4 ranges years respectively. The sex percentage in AIDS affected and HIV+ persons were 90.8% and 9.2% 95.2% and 4.8% male and female respectively. 130 from 1953 HIV+ cases had travel to abroad.
Hamidreza Shetabi, Seyed Morteza Haidari , Darush Moradi Farsani , Zahra Bechari,
Volume 79, Issue 1 (April 2021)
Abstract

Background: Phacoemulsification surgery is one of the most common surgeries in the world. Various drugs have been used alone or in combination with each other to provide effective and safe sedation in patients, but so far, a drug method agreed upon by anesthesiologists has not been proposed. The purpose of this research was to evaluate the sedative quality of midazolam or propofol with a low dose of ketamine in phacoemulsification surgery.
Methods: This study was a double-blind randomized clinical trial conducted from November 2017 to August 2019 at Faiz Hospital, Isfahan. In this study, 68 patients were assigned in the groups of midazolam (M) and propofol (P) using randomization software entered the study. The midazolam (M) group received 0.04 mg/kg and the propofol (P) group received 0.5 mg/kg, then in both groups, ketamine 0.3 mg/kg was injected intravenously. The quality of sedation, cardiovascular response and patient and surgeon satisfaction were assessed and recorded. Data were entered into SPSS 23 software and analyzed by using ANOVA and Independent samples t‐test.
Results: In this study, between the two groups in terms of demographic characteristics there was no significant difference (P>0.05). In the KM group, higher percentage of patients achieved the desired quality of sedation, but, between the two groups no statistically significant difference was shown (P=0.75). Surgeon satisfaction was higher in the KP group (P=0.18) and patient satisfaction was higher in the KM group (P=0.18) but there was no significant difference (P>0.05). Recovery time between groups was Similar and no statistically significant difference was shown (P>0.98). In the KM group at 5 minutes, systolic blood pressure (SBP) was notably greater than the other group (P=0.02) and diastolic blood pressure was notably greater than the KP group (P=0.08).
Conclusion: It can be stated that adding a small dose of ketamine to propofol and midazolam is associated with effective sedation and a similar cardiovascular response during phacoemulsification surgery.
 


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