Nasirian A,
Volume 59, Issue 1 (7 2001)
Abstract
In the past ten years, 45 cases of infantile spasm treated in our center. From these patients, 15 cases received only steroid, other 15 cases only clonazepam, and the rest, a combination of clonazepam and steroid. All patients were observed for two years. This is a retrospective study, the data being extracted from patients' record. A number of patients were treated in ambulatory and the others were patients of the hospital. The result of comparison of optimal control of seizures are as follow: 1) In "only steroid group" 27 percent of the patients were free of seizure, 2) In "only clonazepam group" 28 percent showed no seizure, 3) in "combined clonazepam and steroid group" 39% were seizure-free. Based on this trial we believe that treatment of infantile spasm with combined steroid and clonazepam is better than any of them alone. Considering these results, we believe that the treatment of infantile spasm with a combination of steroid and clonazepam is preferable to these drugs.
Rafiei M, Sadr Bafghi Smh, Nasirian M, Namayandeh Sm, Abdoli Am, Sadr Bafghi Sm,
Volume 66, Issue 7 (6 2008)
Abstract
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Background: Atherosclerosis and the side effects thereof
are a major cause of mortality and morbidity in diabetic patients. Diabetic
dyslipidemia is defined by a decrease in blood levels of HDL cholesterol and increases
in triglycerides and LDL
cholesterol. Diabetic dyslipidemia is
atherogenic, inducing cardiovascular disease in diabetic patients at a
frequency that is two to three times greater than that of nondiabetics.
Methods: This study analyzes
the data from the first phase of the Yazd Healthy Heart Program, a community
intervention project focused on the prevention of cardiovascular disease. Using
the cluster sampling method, we analyzed data from 2000 subjects from Yazd, Iran,
ranging in age from 20
to 74 years. Clinical and
paraclinical data were recorded by trained health providers using a
questionnaire with over 700
items.
Results: The most frequent
lipid disturbance was TG>150 in 67.1% of the type-II diabetic patients (p<0.000), 54.6% of whom were unaware
of their TG level. The mean lipid
and TG levels are
significantly higher (p<0.000). Furthermore, women as a group have higher mean cholesterol, LDL-C and HDL-C levels than men (p<0.000). Additionally, diabetic patients were more obese than the
nondiabetic population. (p<0.000).
Conclusion: The high prevalence of
diabetes mellitus in Yazd and hypertriglyceride-mia among diabetics in this
city, in addition to the lack of awareness among more than half of these patients
about their illness and diagnosis, indicate an urgent need to immediately
control dyslipidemia in these high-risk patients.
Mahsa Hojjati, Mahshid Rashidi, Ali Asghar Khaleghi, Maryam Nasirian, Seyed Hassan Faghihi, Masoud Mohammadi,
Volume 83, Issue 3 (June 2025)
Abstract
Background: Trichomonas vaginalis is one of the main causes of vaginitis and cervical inflammation worldwide. Almost half of sexually transmitted and curable diseases worldwide can be assessed through the examination of this disease, so the aim of this study is to determine the prevalence of trichomoniasis in Iranian women.
Methods: This study is a review of the SID, PubMed, Science Direct, and Google Scholar databases, conducted up to September 2023. The extracted data were analyzed using CMA software (version 2). A search of articles in Science Direct, SID, PubMed, and Google Scholar databases was conducted in accordance with the PRISMA statement criteria, including systematic search, screening of articles, and selection of appropriate studies. The words used for the search and final review in this systematic review were determined based on MESH Terms in the PubMed database. These keywords that were used and selected in this study were in English and Persian. The final information obtained from the studies was reviewed and analyzed using the Comprehensive Meta-analysis (CMA, Version 2) software, and finally the heterogeneity of the studies was examined with the I2 test.
Results: Based on the search for studies and their screening, 22 studies were finally included in the meta-analysis. This study included a sample size of 49,990 Iranian women who were included in the study. In the heterogeneity analysis based on the studies obtained, the heterogeneity was 99.7. Due to the heterogeneity of the studies, the random effects method was used for the final analysis. The prevalence of Trichomonas vaginalis in Iranian women was reported to be 9.3 (95% CI: 4.6-18) based on the 22 final studies and meta-analysis. The publication bias analysis indicated the absence of bias in the studies (p: 0.175).
Conclusion: Based on the prevalence report in the meta-analysis, a relatively high prevalence was reported in Iranian women, and this situation requires more awareness raising through health centers to families, as well as care and screening of women in these centers and also in obstetric centers.
