Showing 3 results for Noroozian
Shahsavand E, Noroozian M, Faiiazi M,
Volume 60, Issue 1 (13 2002)
Abstract
Schizophrenia is one of the most important and disabling mental disorders in the world. Males and females are equally affected. Diagnosis is a very difficult problem in this disorder. Because the diagnostic systems such as ICD-10 and DSM-IV are mainly subjective, they are not valid and reliable. Essentially, in the future, we will need to more objective criteria in psychiatry especially in diagnosis of schizophrenia. Neurological soft signs are an example of these objective criteria. In this study we evaluated the prevalence of neurological soft signs in schizophrenic patients and compared it with the prevalence of these signs in other psychotic patients (except mood disorders with psychotic features) and normal subjects.
Methods: We compared the neurological soft signs (sensory motor integration, motor. Coordination, consequent complex motor acts, primary reflexes, and eye movements) in 30 schizophrenic patients, 30 other psychotic patients (other than mood disorders with psychotic features) and 30 normal subjects. Diagnosis of schizophrenia and also other psychoses were based on DSM-IN criteria. Normal subjects have been selected form the staff of Roozbeh hospital randomly.
Results: The difference between the means of motor coordination subscale of neurological soft signs in schizophrenia and other psychotic disorders (other than mood disorders with psychotic features) were significant (P value < 0.04). There were no significant differences between the means of other subscales of neurological soft signs in two groups of patients.
Conclusion: There are some disturbances of motor coordination subscale of neurological soft signs in patients with schizophrenia. It seems that, these disturbances are evidence of involvements of basal ganglia, motor cerebral cortex, and cerebellum. So it may be suggested that motor coordination as a marker can be used in differentiation between the schizophrenia and other psychotic disorders.
Sikaroodi H, Noroozian M, Aram S,
Volume 67, Issue 9 (6 2009)
Abstract
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Background: It is a well known fact that language functions are
primarily related to the left hemisphere in right handed individuals, there is
still no agreement about hemispheric language dominance in left handers. The
aim of this study is to evaluate the possibility of using functional Transcranial
Doppler ultra sonography (TCD), as a non-invasive method for investigation of
hemispheric language dominance and also to explore possible gender influence on
hemispheric language representation.
Methods: We performed functional TCD during a word generation task, in 62 healthy volunteers (30 right handers and 32 left handers, 50% male and 50% female). All subjects were medical students in the
age range of 22-29 years. Right or left handedness was determined using
Edinburgh questionnaire. Two subjects were excluded from the study because of
poor temporal windows. Mean blood flow velocity was measured in both right and
left middle cerebral arteries (MCA) at rest and during a word generation task, and
changes in flow velocities were compared.
Results: Increase of MCA blood flow velocity was observed in 55% (33 subjects) of the students in the left side, and in 45% (27 subjects) of them in the right side. Right
hemispheric dominance was observed in 43.3% of right handers and 46.7% of left handers. Left hemispheric dominance was
observed in 56.7% of right handers and 53.3% of left handers. Our results showed no significant
right hemispheric language dominance in left handed subjects.
Conclusion: This study does not show significant difference in
hemispheric language dominance between right and left handers, using functional
TCD
Reza Karbasi-Afshar , Reza Noroozian , Ayat Shahmari , Amin Saburi ,
Volume 71, Issue 3 (June 2013)
Abstract
Background: Sympathetic complex of over-activation kidneys is one of the main causes of primary hypertension (HTN). We aimed to assess the efficacy and safety of sympathectomy using 5Fr mariner catheter ablation on patients with refractory hypertension.
Methods: In this prospective cohort study, patients who received three or more anti-hypertensive medications with 160mmHg systolic blood pressure (BP) or more were randomly included and divided into 2 groups. Cases in the first group were undergone to renal denervation and the second group was treated by previous antihypertensive medications. Both groups were followed for six month by assessing BP and adverse effects.
Results: One hundred and seventeenth patients (54%) out of 212 screened patients were included in the first group (renal denervation) and 95 patients as the second group. The mean of BP changes in the first group was 35/15 mmHg with standard deviation of 22/11mmHg. (P<0.001) in the second group, the mean changes of BP was not statistically significant. (5/0mmHg± 22/11, P=0.79 for systolic BP and P=0.96 for diastolic BP). 92% of 117 patients in the first group had a favorable BP decrease, which was defined as a 20mmHg or more decrease in BP, in comparison with 15% of 95 patients as controls (P=0.001). There was no observed complication after denervation in the first group.
Conclusion: It seems that the sympathetic renal denervation can be an effective and safe method for treatment of refractory hypertensive patients indeed of routine medications although further studies with longer follow up duration and more cases are suggested for confirming this issue.
