Search published articles


Showing 10 results for SZ
Malignant pleural mesothelioma: Clinicopathologic and survival characteristic in a consecutive series of 40 patients
Bagheri R, Haghy Sz, Rahim Mb, Attaran D, Silanian Toosi M,
Volume 67, Issue 2 (5 2009)
Abstract

Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 Background: Pleural malignant mesothelioma is an uncommon but extremely invasive tumor which originates from mesothelial cells and usually occures after prolonged exposure to asbestos. The aim of this study was to clinicopathologically evaluation of 40 patients with pleural malignant mesothelioma and the main factors influencing their prognosis.
Methods: In this study patients with definitive diagnosis, who had been followed up for at least three years were studied based on gender, age presenting symptoms, and clinicopathological patterns.
Results: Male to female ratio of the study patients was three to one any the average age of them was 55 years. Chest pain was the most common symptoms in 34(85%) patients. Most of the study patients were in Buchard stage I (37/5%) and the epithelial form was the most common pathological pattern 25(62.5%). 19(47.5%) of cases received only radiotherapy and chemotherapy. Extrapleural pneumonectomy was performed on eight (20%) patients, seven (17.5%) patients underwent decortication and pleurectomy beside adjuvant therapy and 15% of the cases rejected any type of treatment. Surgical mortality occurred in one patient and the most common surgical complication was wound infection. The average survival rate was 12±1.2 months and the main factors influencing it were the patient's physiologic status, pathological form, stage of the disease and the pattern of pleural involvement.
Conclusions: Because the low survival rate after multimodality invasive treatments in mesothelioma, aggressive therapeutic methods were recommended in selected patients


The role of ultrasonographic guided transthoracic needle biopsy in diagnosis of peripheral lung mass
Bagheri R, Haghi Sz, Rahroh M, Kalantari Mr, Sadrizadh A,
Volume 67, Issue 3 (5 2009)
Abstract

Normal 0 false false false EN-GB X-NONE AR-SA MicrosoftInternetExplorer4 Background: Transthoracic needle biopsy is a well established method for obtaining pathologic diagnosis in the lung mass that performed after a previous negative bronocoscopy. The goal of this study is evaluation of the safety and accuracy of ultrasonographic guided transthoracic needle biopsy for diagnosing peripheral lung mass.
Methods: In a descriptive and prospective study from September 2005, 30 patients with peripheral lung mass with greater than 3cm in diameter and less than 5cm distance through the chest wall, underwent ultrasonographic guided transthoracic needle biopsy and it's diagnostic accuracy and complications were analyzed.
Results: The male to female ratio was two to one, the average age of the patients was 61.2 years and 60% of the lesions were located in right side. Adequate biopsy specimens were obtained in all patients, but transthoracic needle biopsy was diagnostic in 86.6% and 13.3% patients because doubtful diagnosis, who underwent thoracotomy for definitive diagnosis. From these four (13%) patient who needed thoracotomy definitive diagnosis were organized embolism, granulomatouse tuberculosis, bronchoalveolar carcinoma, and metastatic adenocarsinoma. Pathological diagnosis were malignant lesion in 83.3% that squamouse cell carcinoma and adenocarcinoma were the most common malignancies and benign lesions were found in 16.6% that granulomatouse tuberculosis was the most common lesion. Complications were observed in 13.3% that included pneumothorax (6.6%) and hemoptysis (6.6%) that managed medically. No cases of mortality were observed.
Conclusion: Transthoracic needle biopsy with ultrasonographic guide due to appropriale diagnostic accuracy and low complication rate with low cost and availability is recommended for the diagnosis of peripheral lung mass.


Evaluation of motor control following thenar muscle fatigue using symmetrical index
Talebian S, Olyaei Gr, Abbaszadeh M, Partabian L,
Volume 67, Issue 5 (6 2009)
Abstract

Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: Muscle weakness and fatigue are two factors that cause muscle injuries. The roll of motor control is important in regulation and reduction of this effect. Repetition of motion after muscle fatigue is due to the significant role of motor control system. The aim of this study was to evaluate the quality of roll control of central nervous system following fatigue in order to answer primary questions in therapeutic exercises.
Methods: Twenty voluntary healthy subjects participated in this study. Dominant abductor policis brevis after surface electromyography (SEMG) of maximal voluntary contraction (MVC) fatigued by maximum three minutes isometric contraction in specific hand splint monitored by dynamometer until reduction of activities to 50% MVC. Before and immediately after fatigue test, 5 dynamic full range of motion in abduction direction performed without resistance and muscle activities recorded by SEMG. Three middle muscle activities selected for comparison of Symmetrical Index (SI) as specificity of motor control assessment. Fatigue indicators were percentage of reduction of MVC and median and mean frequency of power spectrum of MVC before and after fatigue test.
Results: Significant reduction of MVC (46.77%), median (13.03%) and mean (12.20%) frequency were showed (p=0.001), whereas significant increase of SI (10.76%) appeared (p=0.000), following fatigue test.
Conclusion: Fatigue reduces muscle contraction velocity, therefore median and mean frequency decrease. Also after muscle fatigue reduces of muscle proprioception sense appears, that can cause slow dynamic joint motion. Upper central control systems try to correct this situation by involving new motor units and changes of muscle timing. Synchronization of primary and new motor units plays an important role in increase of SI.


Pulmonary Hydatid cyst: analysis of 1024 cases
Bagheri R, Haghi Sz, Amini M, Fattahi As,
Volume 68, Issue 3 (5 2010)
Abstract
Background: Pulmonary hydatic cyst is a common parasitic disease and health care problem in developing countries. In our study we assessed treatment outcomes of pulmonary hydatic cyst in our area. Methods: All patients presenting to Ghaem, Omid and Mehr hospitals of Mashhad- Iran since 1981 to 2008 with pulmonary hydatic cyst were enrolled in this study and demographic data, location and number of cysts, diagnostic methods, type of operations, out comes and rate of recurrence were statistically analyzed. Results: One thousand and twenty for patients enrolled in this study. The mean age was 30.6±16.1 years and male to female ratio was 1.2. The most common symptoms were cough (55.1%) and chest pain (33.8%). 53.8% of the patients had right side involvement, 40% had left side involvement and 6.2% had bilateral disease. Inferior lobe was the most common involved lobe. The cyst was intact in 52.6% and the other cases were complicated or perforated. The most common surgical technique was removing the cyst membrane without resection of pericyst and closure of air leaks (67.2%). The cyst was enucleated in 21.2% and parenchymal resection was performed in 10.3%. The mortality rate was 0.2% and morbidity occurred in 8.4% of patients. The most common complications were dead-space in pulmonary parenchyma in 3.4% of cases and wound infection in 1.5%. Conclusion: The best treatment for pulmonary hydatic cyst disease is surgery with low mortality and morbidity. The most common treatment is extraction of cyst membrane and closure of small air ways. Pulmonary resection should be reserved for complicated forms of disease.
A 10-years study of paranasal sinuses osteomas in Amir Alam Hospital, Tehran: a brief report
Naraghi M, Madani Kermani Sz, Mohammadnezhad Sf,
Volume 69, Issue 10 (5 2012)
Abstract

Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: Osteoma is a bony slow growing benign tumor in one of the sinuses. It is usually asymptomatic but clinical symptoms will occur by its overgrowth, occupation of sinus space and obstruction of ostia.
Methods : This descriptive, cross-sectional, retrospective study was done by accessing the medical records of 17 patients with paranasal sinuses osteomas admitted in Tehran Amir Alam Hospital during 1999-2008.
Results : The mean age of the participants was 33.9 years and 12 (70.6%) were male and 5 (29.4%) were female. No positive family histories existed for the lesions. The mean time interval between the onset of symptom and attending the hospital was 4.4 years.
Frontal followed by ethmoid sinus osteomas were more common in comparison to other sinuses. The most reported symptoms in frontal sinus osteomas were upper eyelid inflation and headache and proptosis, nasal congestions and diplopia in ethmoid sinus osteomas. Most patients had been endoscopically treated.
Conclusion: In small-to-medium-sized osteomas with no invasion into orbit or skull base, endoscopic surgery is the treatment of choice with minimum side-effects.


Evaluation of the effect of an intradermal injection of Wharton's jelly-derived mesenchymal stem cells in diabetic wound healing in animal model
Sona Zare, Rahim Ahmadi, Abdolreza Mohammadnia , Mohammad Ali Nilforouszadeh, Minoo Mahmoodi,
Volume 78, Issue 12 (March 2021)
Abstract
Background: The application of mesenchymal stem cells in the healing of chronic wounds is one of the most challenging issues in cell therapy. The present study investigated the efficacy of intradermal injection of umbilical cord Wharton's Jelly-derived mesenchymal stem cells in diabetic wound healing using ultrasound imaging in an animal model.
Methods: During this experimental laboratory study that was performed in the Skin and Stem Cell Research Center, Tehran University of Medical Sciences between October 2017 and October 2016, mesenchymal stem cells were isolated from umbilical cord Wharton's jelly of 10 neonates. The cells were passage. The differentiation potential of cells to osteocyte and adipose cells was evaluated. The expression of specific markers of mesenchymal stem cells was evaluated using flow cytometry. The viability and quality of cells were evaluated before transplantation. The diabetes model was developed by intraperitoneal injection of streptozotocin in 42 male Wistar rats. The animals were randomly divided into two groups: normal saline injection (control) and cell injection. Cell transplantation was performed intradermally. Skin thickness and density were assessed using ultrasound imaging on days 7, 14 and 21. Finally, the data were analyzed using a t-test and analysis of variance.
Results: Injection of mesenchymal stem cells caused faster closing of the wound. The results of biometric measurement of wound skin in rats showed that skin thickness and density on days 7, 14 and 21 in the Wharton jelly mesenchymal stem cell injection group had a significant increase compared to the control group.
Conclusion: The results of cell analysis showed that the isolated cells are the same as mesenchymal stem cells. The cells were of the required health and quality. Intradermal injection of mesenchymal stem cells in diabetic wound area caused faster healing in diabetic rats, according to which, such stem cells can be considered in cell therapy, especially in the field of chronic wound healing.

Variation in the forearm extensor muscle: case report
Reza Soltani, Fakhroddin Aghajanpour , Mohsen Norozian, Gholamreza Hasanzadeh, Hojjatallah Abbaszadeh, Fatemeh Fadaei,
Volume 79, Issue 1 (April 2021)
Abstract
Background: The Extensor Carpi Radialis Longus (ECRL) and the Extensor Carpi Radialis Brevis (ECRB) are muscles of the posterior forearm compartment. variations in this area of the forearm are common and are usually diagnosed during surgery. Sometimes these variations are symptomatic and can be helpful in clinical procedures such as surgery. Diagnosis and identification of abnormalities can be used in academic studies to evaluate limb function. Reporting such variations is important in clinical practice and will help treat limb dysfunction. In this report, we report two cases of ECRL and ECRB muscle tendon variations in the upper third of the forearm.
Case presentation: During routine dissection of the body of a 70-year-old man fixed in 10% formalin in the Department of Biology and Anatomy, Shahid Beheshti University of Medical Sciences, Tehran, two cases of ECRL and ECRB muscle tendon variations were observed in the upper third of the left forearm. The fascia of the ECRL and ECRB muscles were separated, and following the ECRL muscle from the external epicondyle of the humerus to the outer third of the forearm, we observed that the tendon of this muscle was divided into two branches. We also observed that the ECRB muscle tendon split into two branches slightly below its origin. The branch had moved obliquely toward the lower end of the radius. at the lower end of the forearm, this tendon was connected to the ECRL muscle tendon by passing over the sub-branch of the ECRL muscle tendon and the depth of the retinaculum extensor. The submandibular tendon was attached to the base of the second Metacarpal bone along with the ECRL muscle tendon. The main branch of this muscle also had its main path to the lower end of the forearm. The lower end of the forearm was connected to the dorsal base of the second and third metacarpals by passing under the retinaculum extensor.
Conclusion: Knowing these variations can help radiologists and surgeons in diagnosis and treatment.

Variation in median nerve nutritional artery at the distal end of forearm: case report
Fakhroddin Aghajanpour, Reza Soltani, Azar Afshar, Hojjat Allah Abbaszadeh, Reza Mastery Farahani, Mohsen Nourozian,
Volume 79, Issue 4 (July 2021)
Abstract
Background: The median nerve is one of the most important branches of the brachial plexus. Due to the role of the median nerve in sensory and motor innervation of the forearm and hand in the upper limbs, its blood supply is very important. Awareness of variations in the blood supply pattern to this nerve reduces the incidence of necrosis and ischemia of the nerve during surgical and diagnostic procedures.
Case Presentation: During routine dissection of the cadaver of a 65-year-old man fixed in formalin (10%), in the Department of Anatomy and Reproductive Biology, Shahid Beheshti University of Medical Sciences, a rare variation was observed in the median nerve nutritional artery at the distal end of the left forearm. After dissection of the skin, superficial and deep fascia, anterior compartment forearm muscles, nerves and blood vessels were exposed from surrounding tissues. The median nerve passed through the two heads of the pronator teres muscle and left the cubital fossa in the depth of the flexor digitorum superficialis and the surface of the flexor digitorum profundus in the forearm. It was observed that at the distal end of the left forearm between the flexor carpi radialis and the flexor digitorum superficialis, a relatively thick branch originates from the radial artery and supplies blood to the median nerve. This branch was separated from the radial artery (before the artery enters the anatomical snuffbox) and crossed the surface of the flexor carpi radialis muscle and inserted into the median nerve sheath. In the forearm, this branch was the only artery supplying blood to the median nerve.
Conclusion: Due to the superficial position of the median nerve at the distal end of the forearm, physical damage to the nerve and its nutritional artery leads to necrosis and ischemia of the nerve, and ultimately disturbed the transmission of sensory and motor messages.

Frequency of causes of otalgia in patients referred to the ENT clinic: a brief report
Mohamad Ali Damghani , Ayeh Shamsadini , Elham Abbaszade,
Volume 81, Issue 6 (September 2023)
Abstract
Background: Otalgia is defined as pain localizing in the ear that can be primary or referred. By careful history and physical examination, all causes in this extensive differential diagnosis can be excluded. Given that otalgia is one of the most common causes for patients to visit the clinic and has a wide variety of differential diagnosis, the purpose of this study is to investigate the frequency of different etiologies of ear pain in patients referred to referral clinic.
Methods: This cross-sectional study was performed on patients presenting with otalgia. After entering the study, the patient underwent a thorough examination of the ear, nose, throat, head and neck, teeth and salivary glands by a resident under the supervision of a senior otologist, and based on the findings, relevant para clinical procedures such as x-ray, CT scan or stroboscopy were performed. Data collection was done based on a data log check list. Samples were collected during six months. SPSS software version 20 was used for analyses.
Results: The most common causes of otalgia were acute otitis media 29%, external otitis 17% and chronic otitis media 15%. Cerumen and referral ear pain were next in line (13.5%). There was significant relationship between otalgia with age groups (The age between 13 and 30 years were the most referred due to otalgia). There was no significant relationship between otalgia and gender, underlying disease, economic status, smoking and opium use.
Conclusion: Given that otalgia is a common complaint in patients referred to the clinic, knowing its causes and origin is useful in diagnosing, proper treating it and avoiding unnecessary para clinical procedures and empirical treatment. The most common causes of otalgia in this study were acute otitis media, otitis externa and chronic otitis media, respectively. Referral otalgia and cerumen impaction were the next causes. Among the age groups, the age between 13 and 30 years were the most referred due to otalgia, but there was no significant relationship with any of the variables of gender, economic status and smoking and opium use.

An overview on hyperthyroidism: pathogenesis, diagnosis ,management, complications and prognosis: a review article
Sahar Karimpour Reyhan , Mahsa Abbaszadeh, Alireza Esteghamati ,
Volume 83, Issue 1 (April 2025)
Abstract
Hyperthyroidism is one of the most important endocrine disorders, characterized by increased activity of the thyroid gland and excessive production of thyroid hormones. These hormones play a key role in regulating the body’s metabolism; therefore, their excess leads to a wide range of clinical manifestations. The most common symptoms include anxiety, restlessness, weight loss despite normal or even increased appetite, palpitations, excessive sweating, fine tremors of the hands, sleep disturbances, and heat intolerance. Some patients may also experience mood changes such as irritability and nervousness. On physical examination, rapid tendon reflexes, tachycardia, moist and thin skin, and in many cases the presence of goiter (thyroid enlargement) may be observed. The condition is more common in women than men and is most frequently seen between the ages of 20 and 50 years. Once hyperthyroidism is confirmed, the underlying cause of thyrotoxicosis must be determined. The most common cause is Graves’ disease, an autoimmune disorder that leads to diffuse thyroid enlargement and overproduction of hormones. Toxic multinodular goiter and solitary toxic adenoma are other important causes. For definitive diagnosis, blood tests measuring TSH, T3, and T4 are essential. In hyperthyroidism, TSH is typically suppressed while T3 and T4 are elevated. In addition to laboratory testing, thyroid ultrasound can help evaluate the structure of the gland, and a thyroid radioactive iodine uptake scan can further differentiate between different causes and determine disease activity. Several treatment options are available for managing hyperthyroidism. Antithyroid drugs such as methimazole or propylthiouracil inhibit the synthesis of thyroid hormones. Beta-blockers are often prescribed to control cardiovascular symptoms and reduce palpitations. Radioactive iodine therapy is a common and effective method that destroys the overactive thyroid tissue. In rare cases, or when other treatments fail, thyroidectomy (surgical removal of part or all of the thyroid gland) may be required. Overall, hyperthyroidism is a manageable condition, but it requires accurate diagnosis, careful selection of therapy, and close follow-up with a specialist. Patient cooperation and adherence to treatment play a crucial role in controlling symptoms and preventing long-term complications. This review will focus on describing the symptoms, causes, diagnostic methods, and treatment options.

Page 1 from 1     

© 2026 , Tehran University of Medical Sciences, CC BY-NC 4.0

Designed & Developed by : Yektaweb