Showing 5 results for Saadati
Rahimifard N, Fatholahzadeh B, Pirali Hamedani M, Noory Z, Saadati Sh, Zavar M, Pirouz B, Asghari Sh, Khezripour M, Saberi S,
Volume 65, Issue 8 (3 2007)
Abstract
Background: Bacillus cereus spores distribute widely in nature and can be isolated from different kinds of foods. This bacterium can produce diarrhea and emetic enterotoxins and syndromes. As infants are known to be more susceptible to B. cereus infection due to their incomplete intestinal flora and fast growth of this bacterium during consumption, it is very important to investigate the presence of B. cereus in infant formula and possible pathogenicity of this microorganism in infants.
Methods: In this study, 60 samples of infant formula were examined for the presence of B. cereus. From a 1/10 dilution of each sample, a total amount of 1 ml was inoculated onto four phenol red agar plates containing mannitol, egg yolk emulsion and polymyxin B sulfate. The plates were incubated at 30°C for 24 hours. Confirmation tests were then performed on suspected colonies.
Results: Among the 60 samples, 11 samples had more than 10 cfu/g, four of which contained more than 102 cfu/g. The other 49 samples showed less than 10 cfu/g of B. cereus.
Conclusions: We suggest that for infant formula the maximum microbial limit be reduced to less than 10 cfu/g to control B. cereus contamination and to prevent infection in infants. For this purpose, infant formula should be tested by the method and confirmation tests used in this study. In addition, susceptibility to penicillin, ß-hemolysis and growth rate at 45ºC could also be performed.
Haghighi S, Yaghmaei P, Hashemi F, Saadati N, Ramezani Tehrani F, Hedayati M,
Volume 70, Issue 5 (5 2012)
Abstract
Background: Adipokines are proteins which are secreted from the adipose tissue. These groups of proteins are involved in the control of metabolism. Chemerin is one of these adipokines with different proposed biological roles. Serum levels of chemerin have been associated with increased body mass index, insulin resistance, metabolic syndrome, diabetes and cardiovascular diseases. The aim of this study was to assess the association between serum chemerin concentrations and polycystic ovarian syndrome.
Methods: This case-control study was performed in Taleghani Hospital in Tehran, Iran during 2011. On 45 patients with polycystic ovarian syndrome and 45 normal individuals as the control group. The participants were selected by easy given sampling method. Body mass index, fasting chemerin and serum insulin concentrations were measured by Enzyme-Linked Immunosorbent Assay (ELIZA) method. Fasting serum glucose was measured by the enzyme-calorimetric method and insulin resistance index (HOMA-IR) was measured by the calculation of relevant equation. Data was analyzed using independent t-test and Pearson's correlation coefficient by SPSS version 18.
Results: Serum chemerin, insulin, and glucose concentrations were significantly higher in patients with polycystic ovarian syndrome than the control group. There was no significant correlation between body mass index, serum levels of insulin, glucose, HOMA-IR, or chemerin in cases and controls.
Conclusion: This study showed that serum chemerin levels increase in polycystic ovarian syndrome. The findings also suggest that changes in chemerin serum levels could be considered as a criterion for polycystic ovarian syndrome.
Razieh Mohamad Jafari, Mehrnaz Taghvai Maasomi , Mahin Najafian , Najmie Saadati ,
Volume 72, Issue 7 (October 2014)
Abstract
Background: Previous investigations have shown that pregnancy-associated plasma protein-A (PAPP-A) levels are associated with adverse pregnancy outcomes including intrauterine growth restriction (IUGR) fetuses as well as preterm delivery. The aim of this study was to determine the rate of preterm delivery in women with low PAPP-A and at intermediate risk for chromosomal abnormalities in the first trimester screening.
Methods: A total of 137 women who underwent Down syndrome screening between 11 to 14 weeks of gestation were studied from September 2011 to September 2013 at Perinatal Care Clinic, Imam Khomeini Hospital, Ahvaz, Iran. From those, 52 patients had low PAPP-A. Inclusion criteria were singleton pregnancies, at 11 to 14 weeks of gestation, at intermediate risk for Down syndrome (risk in 1:101 to 1:1000). The intermediate risk was estimated based on maternal parameters, maternal serum markers (PAPP-A and β-hcG), and nuchal translucency (NT) using fetal medicine foundation (FMF), UK) software. The power of the study was 90%. The sample size was estimated based on prevalence of preterm delivery in pregnancies with low PAPP-A in the first trimester screening. Patients were followed-up until delivery to observe pregnancy outcomes. We evaluated the variables such as level of PAPP-A, outcomes of delivery, age, β-hCG, and gestational age.
Results: Among 137 normotensive pregnant women at intermediate risk for Down syndrome, 52 cases (38%) had low PAPP-A (<0.4 MoM). Of 52, 14 cases (27%) had preterm delivery. None of our patients had pregnancy related or non related diabetes, preeclampsia, or chromosomal anomalies. 45 cases (86%) from 52 patients were equal or less than 35 years, while 7 patients were more than 35 years. Among 52 followed-up patients, 48 patients (92.4%) were at low-intermediate risk (risk in 1:251 to 1:1000), and 4 cases (7.6%) were at high-intermediate risk (risk in 1:101 to 1:250).
Conclusion: We found high frequency of preterm delivery in pregnant women with low PAPP-A level at the first trimester screening. Hence, this group of patients needs special and early preventive management. Furthermore, we suggest that future researches to be conducted with larger sample size and also cervix length measurement to be included.
Seyed Mohammad Riahi , Hossein Mozafar Saadati , Maryam Mohammadi , Farin Soleimani ,
Volume 77, Issue 4 (July 2019)
Abstract
Background: Anemia is one of the most important nutritional disorders among children and adolescent in Iran and developing countries. Despite the possibility of anemia prevention, there is a high proportion of this problem in school children and especially infants. The aim of this study was to determine the prevalence rate of anemia in 6 to 12 months old children.
Methods: This was a cross-sectional study that conducted between May 2016 and October 2016 in Tabas health centers, South Khorasan, Iran. In this study 911 infants aged 6 to 12 months were enrolled by census method. Demographic variables and all blood factors were collected through interviews and laboratory tests in Tabas health centers, respectively. In this study, cut-off point of <11 g/dl for hemoglobin was considered as anemia index. All Statistical analyses were done using descriptive statistics, chi-square tests and Pearson correlation in SPSS software, version 22 (SPSS Inc., Chicago, IL, USA). P-value of 0.05 was considered as level of statistical significance.
Results: The mean age of individuals was 9±1.5 months, the mean current weight and the mean weight at birth time were 8678±1112.1 g and 3090±467.9 g, respectively. According to World Health Organization (WHO) criteria, the prevalence rate of anemia in Tabas City was estimated 37.1%. The prevalence rate of anemia in age groups based on hemoglobin, mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) indices had a significant decreasing trend (P=0.001). Prevalence rate of anemia in males and females was not significantly different (P=0.27). Moreover prevalence rate of anemia was higher in rural areas rather than urban areas (P=0.009).
Conclusion: This is the first assessment of anemia prevalence among children in east of Iran. As a result of estimated prevalence of anemia, based on WHO definition, revealed moderate public health importance among infants aged 6 to 12 months old. The deceasing trend of anemia based on age groups indicates the importance of iron supplementation in Iran, especially in developing countries.
Fatemeh Beitsayah, Najmieh Saadati , Mojgan Barati ,
Volume 82, Issue 1 (April 2024)
Abstract
Background: Maternal and neonatal complications in twin and multiple pregnancies are higher than in singleton pregnancies. The purpose of this study is to investigate maternal and neonatal outcomes in twin or multiple births.
Methods: In this descriptive and analytical study, 266 pregnant women with twins and multiples were selected in a goal-based manner who had medical records in Imam Khomeini Hospital in Ahwaz from March 2020 to March 2022. This study is based on the purpose of selection and then the required information was extracted from the archive department of Imam Khomeini Hospital in Ahwaz. A two-part checklist was used to collect data, and then the collected information was analyzed by descriptive and analytical statistical tests.
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Results: The observations of this study show that the highest frequency of the total number of births is from March 2020 to March 2021 (6729 people), while the highest ratio of the number of twin or multiple births to the total number of births is from March 2021 to March 2022 (4.63 percent). The frequency of stillbirths is the highest from March 2021 to March 2022 (62.96 percent). There is a significant difference in fetal complications of twin and multiple births, premature birth, low birth weight and intrauterine growth delay between twin and multiple births (P-value<0.05) and for fetal anomaly and death from March 2021 to March 2022. Comparison of the two years under study shows no significant difference was observed between twin and multiple births (P-value>0.05). Pre-eclampsia was observed in 7.8 percent for twin births and 6 percent for multiple births, which statistically has no significant difference between them (P-value=0.331) and for diabetes, placental abruption and placenta Previa. There is a significant difference between twin and multiple births (P-value<0.05).
Conclusion: The frequency of multiple pregnancy shows an increase compared to previous studies in Iran, and prevention of premature birth and careful monitoring of the fetus can improve the outcome of twin or multiple births.
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