Parviz Karimi, Hossein Seidkhani, Zahra Mohebinejad, Shayan Hasanvand,
Volume 83, Issue 4 (July 2025)
Abstract
Background: Seizures are common neurological disorders in childhood, with a prevalence of 4 to 6 cases per 1,000 children in the community. This study was conducted to evaluate the prognosis of the first non-provoked seizure in terms of recurrence.
Methods: In this descriptive-analytical study, the records of all patients hospitalized with a diagnosis of seizure without a trigger for the first time at Imam Khomeini Hospital in Ilam from April 2016 to March 2019 were reviewed retrospectively. Information was extracted from the patients' records. All records were reviewed in terms of seizure type characteristics.
Results: The results of imaging with seizure recurrence in these patients showed that there was a significant relationship between the result of the first imaging and the report of seizure recurrence (P≥0.001 and Phi-Cramers=0.729). Since EEG of all patients was not recorded, they were excluded from the study. There was also a significant relationship between drug treatment and seizure recurrence at a significance level of 5% (P=0.004 and Phi-Cramers=0.273). This study showed that among the 64 patients who had started drug treatment, 44 reported no seizure recurrence and 20 reported seizure recurrence, and among the 54 patients who had not received drug treatment, 23 reported no seizure recurrence and 31 reported seizure recurrence. In the first year, the highest frequency of seizure recurrence was in the first 6 months. With increasing time after seizure, the rate of seizure recurrence decreased. The highest percentage of seizures without a triggering factor was in the age group of 5-10 years and the lowest percentage was in the age group under 5 years.
Conclusion: Identifying key factors associated with seizure recurrence will enable healthcare professionals to tailor their diagnostic and therapeutic approaches, ultimately enhancing patient care and safety. By understanding the importance of family history, seizure characteristics, and neuroimaging findings, clinicians can make informed decisions that may prevent life-threatening complications and minimize cognitive impairment in affected children.
Aref Teymurinejad, Hossein Seidkhani , Zahra Mohebinejad, Amirreza Eidypou , Hamed Azadi ,
Volume 83, Issue 7 (October 2025)
Abstract
Background: Kidney stones are the third most common urinary tract disorder after prostate disease and infection. Painful attacks are the most common clinical manifestation, which is known as renal colic. The aim of the present study is to determine the effect of pethidine, pethidine and ketorolac, and ketorolac in patients with primary renal colic.
Methods: Renal colic patients at Imam Khomeini Hospital in Ilam from April 2023 and March 2023. were divided into three groups of 36 people. The first group received pethidine 25 mg, the second group received ketorolac 30 mg, and the third group received a combination of 2 drugs. A questionnaire included demographic information of the patients, heart rate, systolic and diastolic blood pressure, respiratory rate, oxygen saturation, side effects, pain intensity, length of hospitalization, and type of treatment received.
Results: After receiving the drug, the average heart rate increased in all three groups. But in group A, this increase was less than two groups, B and C, and this difference was not statistically significant (P=0.34). The average systolic blood pressure before receiving the drug was significantly higher in the three studied groups (P=0.006), which decreased after receiving the drug, but this decrease in systolic blood pressure in the three groups was not statistically significant (P=0.98). The average pain intensity before receiving the drug was 8.56 ± 1.2 in group A, 9.17 ± 0.878 in group B, and 8.86 ± 0.961 in group C. There was no significant difference between the three groups in terms of initial pain intensity (P=0.45). While the average pain intensity after receiving the medicine was significantly reduced and there was a significant difference (P<0.000).
Conclusion: Overall, the obtained results showed that ketorolac and pethidine have a faster effect and power compared to pethidine and ketorolac alone in controlling the pain of patients with renal colic, and the need for life-saving treatment is also less in this drug, and according to numerous studies, its side effects are also less.
