Showing 6 results for Seirafi
H Seirafi , F Farnaghi ,
Volume 56, Issue 3 (1 1998)
Abstract
Tuberculos Gumma is one of the various clinical manifestations of cutaneous TB that is characterized by non tender, undolent subcutaneous nodules which progressively involve the skin and take the appearance of an ulcer. In this article, we present two young patients, affected with tuberculos gumma. One of them, presented with multiple abcesses on the face and extremities, associated with pulmonary involvement and arthritis of the left wrist. The other one had just one subcutaneous nodule on the face, with positive familial history of pulmonary TB and tuberculos lymphadenitis in her two brothers. Both patients were cured with anti TB treatments
Sh Seirafian , B Bastani ,
Volume 56, Issue 4 (1 1998)
Abstract
Some of ICU patients with Acute Renal Failure (ARF) require dialysis. Conventional or intermittent hemodialysis (HD) may cause hypotension and insufficient loss of fluids and toxins from blood. Peritoneal dialysis also my cause peritonitis and has lower efficiency than HD. We did continuous Venovenous Hemodialysis (CVVHD) for three ICU patients with ARF in Saint-Zahra Medical Center for the first time in our country. Method and Material: With a polysulfone membrane, blood pump, peritoneal dialysis solution, heparin, and a fix nurse, HD was done for 12-24 hours. Results: 1) Urea clearance was 18-50 ml/h. 2) Ultrafiltration was 160-1000 ml/h. 3) With dialysis, hemorrhage, coagulation disorder, and oxygenation recovered. 4) All of patients developed hyperglycemia and hypothermia. 5) All of patients died (two with septicemia and one with hypotension). Conclusion: In the absence of hemodialysis or peritoneal dialysis, CVVHD with present preliminary equipments is suitable and can excrete more toxins and fluids.
H Seirafi , F Farnaghi , M Daneshpazhooh ,
Volume 57, Issue 2 (8 1999)
Abstract
Epidermolysis bullosa (EB) is the term applied to a group of disorders whose common primary feature is the formation of blisters following trivial trauma. Hereditary EB comprises 3 major classes: simplex, junctional and dystrophic, and includes more than 23 phenotypes. The albopapuloid pasini variant of dominant dystrophic EB is characterized by a distinctive clinical appearance. In this article, we report this disease in three members of a family (father and two sons).
H Seirafi , F Farnaghi , H Ghani Nezhad ,
Volume 58, Issue 1 (6 2000)
Abstract
Kindler syndrome is characterized by acral blister formation in infancy and childhood, poikiloderma and cutaneous atrophy. Undoubtedly, similarities of the clinical features exist between Kindler syndrome and Epidermolysis bullosa simplex with mottled pigmentation. In this article, we report 3 patients with Kindler syndrome. Until the Bullous component of Kindler syndrome is more completely understood, we believe that this disorder should continue to be classified as a separate disease.
Shahidi Sh, Seirafian Sh, Shayegan Nia B, Adilipoor H,
Volume 64, Issue 9 (1 2006)
Abstract
Background: Long term use of immunosuppressive therapy in transplant
recipients in order to prevent acute and chronic rejection increases the long
term risk of cancer. This study evaluates the incidence of different organs’
cancer after renal transplantation and immunosuppressive therapy.
Methods: This is a retrospective analysis of malignant tumors in renal graft
recipients with more than one year graft survival. Patients were assessed
according to their age, sex, diagnosis of cancer, immunosuppressive drugs,
donors and period of dialysis before transplantation.
Results: Evaluating all existing files in selected private clinics in Isfahan 350
patients were reviewed and 289 of them had entrance criteria. A total of 186
men and 103 women (mean age: 42.17±13.09 years) were included. They were
followed up over a mean period of 52.46±33.24 months. A total of six cases
(2.1%) of cancer were diagnosed in six recipients: All patients with cancer
were male with a mean age of 51.17±14.7 years (range: 26-68 years). Tumor
presented at a mean time of 51 months (rang: 15-82 months) after
transplantation. There were two patients with BCC, two patients with SCC and
two patients with lymphoma. Two patients died of progressive malignant
disease. Age, period of dialysis before transplantation, and using
immunosuppressive and anti-rejection drugs had no significant impact on
development of post transplant malignancy.
Conclusion: The frequency of tumors in these patients is lower than what
reported by other centers, probably due to short period of follow up and low
incidence of cancer in our general population. The risk of malignancy was 28
fold higher among transplant recipients than in general population. High risk
of cancer in this group, confirms the necessity of routine examination for
organ transplant recipients both before and after transplantation.
Hassan Seirafi , Amirhooshang Ehsani , Mahbobeh Sadat Hosseini, Bahador Samavati , Fatemeh Gholamali , Pedram Noormohammadpour ,
Volume 71, Issue 4 (July 2013)
Abstract
Background: Alopecia areata (AA) is a common cause of noncicatricial alopecia that occurs as a patchy, confluent or diffuse pattern. Exact etiologic factor of AA not yet recognized. Among many hypothesis, relationship between AA and autoimmune disease, especially thyroid disorders, was more interesting. The objective of this study was to determine the prevalence of thyroid test disorders in the patients with alopecia totalis and universalis in comparison with normal population.
Methods: We analyzed medical records of 100 patients, including 44 male and 56 female in Tehran Razi Hospital from 1388 to 1389. The mean age was 24.1 years. Patients having totalis and universalis form of AA considered as case group while 100 normal person (42 male and 58 female with mean age of 26.1) who had not any form of AA considered as control group. Both groups had not any sign of thyroid disease at clinical examination according to their available medical records. Collected data were analyzed statistically in SPSS software 17th version.
Results: In the majority of patients (54%) the disease was manifested in the first two decades of life. History of atopia was seen in 9.8% of patient. Presence of the similar disease in first-degree family members was seen in 14.3% of patients. Abnormal T3, T4 and TSH were significantly higher in case group. Abnormal T3 uptake was higher in case group but not statistically significant.
Conclusion: Paraclinical thyroid disorders were significantly higher in the alopecia areata patients than in normal population. There was no significant association between the age, sex and duration of disease and presence thyroid dysfunction.
