Showing 4 results for Sohrabvand
Sohrabvand F, Shariat M, Fotoohi Ghiam N, Hashemi M,
Volume 67, Issue 2 (5 2009)
Abstract
Background: The
transfer of multiple embryos during ART procedures (IVF/ICSI) in order to
maximize the chance of pregnancy, has resulted in increasing rates of multiple
pregnancies with a 20- fold increased risk of twins and 400- fold increased
risk of higher order pregnancies with significantly high maternal and perinatal
morbidity and mortality in comparison with singleton. Since at present there is
no limitation in number of embryos being transferred in ART cycles in
infertility centers in Iran, in order to evaluate the relationship between
number of embryos transferred, pregnancy rates and multiple pregnancy, this
study was performed in a referral university center.
Methods: In a cross
sectional descriptive analytical study a total of 536 ART cycles in infertile
patients treated at the Infertility Department of Vali-e-Asr Hospital &
Vali-e-Asr Reproductive Health Research Center from October 1999- March 2003 were
evaluated using a questionnaire dealing with the parameters affecting ART
outcome.
Results: There was a
total pregnancy rate of 21% with a multiple pregnancy rate of 12%. Increased
age had a negative effect on pregnancy rate with a significant difference over 40
years (p<0.05). Pregnancy rate was higher with increased number of
transferred embryos but it was only statistically significant when three versus
two embryos were transferred (p<0.008). When more than three embryos
transferred, although there was an increase in pregnancy rate, the difference
was not statistically significant, but there was a significant increase in
multiple pregnancy rate.
Conclusions: The maximum number of transferred embryos in ART cycles should not precede three
embryos especially in age groups less than 40 and also when good quality
embryos are available.
Sohrabvand F, Karimi M,
Volume 67, Issue 9 (6 2009)
Abstract
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Background: Leg cramp is the painful contraction of the muscles
that often occurs at night. Pregnancy is the most common cause of muscle cramps
that usually occur in the second trimester of pregnancy. Although the reasons
of the spasms had not been determined, the imbalance between the absorption and
elimination of serum electrolytes such as Ca, Mg and potassium and also insufficiency of some vitamins
and probably the changes in activities of motor neurons of spinal cord, can be
the source of these problems. The aim of this study was the evaluation of frequency
and predisposing factors of leg cramps.
Methods: In a cross sectional descriptive analytic study, a
group of 400 women in the third trimester of pregnancy were asked
to record the symptoms of leg cramp. Their education level and job recorded and
their total serum level of Ca and Mg was measured in the first visit. Exclusion criteria
included systemic medical conditions such as thyroid disease, diabetes, osteoporosis
and prenatal disorders such as gestational diabetes mellitus and preeclampsia
and patient cooperation.
Results: In our study the prevalence of leg cramp was 54.75%. There was a statistically significant relationship
between leg cramp and serum level of magnesium (p=0.04). There was no relation between calcium serum level
and leg cramp (p=0.294). The women's age, their nutritional habits and
individual characteristics were not signify-cantly related to occurrence of leg
cramp.
Conclusion: Leg cramp is a common
symptom in pregnancy and in patients with low serum levels of magnesium, a
magnesium supplement can be helpful.
Farnaz Sohrabvand , Mohyeddinmahdi Shirazi , Mamak Shariat , Fatemeh Mahdiyin,
Volume 71, Issue 3 (June 2013)
Abstract
Background: We are in new era of knowledge and treatment of women with PCOS. We should find management modalities that can improve their life quality. Due to high prevalence of PCOS, and zinc deficiency in Iran, importance of antioxidants such as zinc on treatment and improvement of PCOS complications, and due to the disadvantages of the current treatment for the disease (i.e. OCPs), finding an efficient alternative therapy with no or less side effects seems to be as important as some methods for changing the life style of these women. This study was performed to assess zinc levels in PCOS versus non PCOS patients to determine if zinc can be helpful in PCOS management.
Methods: This is a case-control study which was performed from January 2012-2013 in 100 infertile women aged 20-45 years who were referred to Vali-e-Asr infertility clinic. Fifty patients had PCOS according to Rotterdam Criteria (case group) and 50 were infer-tile women without PCOS (control group). In both group, serum Zinc levels were deter-mined and the data was gathered using the SPSS software and analyzed by descriptive (percent, mean, standard deviation) and analytical 2, ANOVA, Mann-Whitney and Correlation).
Results: Results did not show a significant difference between case group and control group in respect to serum Zinc levels (P>0/05).
Conclusion: Due to no difference between case group and the control one in zinc levels, it seems that zinc supplementation in PCOS patients is not necessarily useful or of clinical importance. Obviously studies with larger sample size can probably define the role of zinc in these patients.
Farnaz Sohrabvand , Mamak Shariat , Mohammad Jafar Farahvash , Fedyeh Haghollahi , Mahnoosh Khosravi , Masoomeh Maasomi , Maryam Bagheri , Alireza Abdollahi , Akram Sarbiyaie , Fariba Bashari ,
Volume 71, Issue 10 (January 2014)
Abstract
Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Chronic infections have been mentioned as one of the different etiologic factors related to PCOS. Due to the high prevalence of Helicobacter pylori infection especially in developing countries, its probable role in the pathogenesis of PCOS and the limited information available in this area, serologic study of H.Pylori infection in patients with PCOS, was performed.
Methods: This research was performed as a case control study from Dec 2010 until May 2012 in 82 patients (and their spouses) with polycystic ovary syndrome (case group) and 82 non PCOS patients (control group) with an age range of 20-40 referred to Vali-e-Asr Hospital infertility clinic. Both groups and their husbands filled a questionnaire and were examined by testing their serum H.Pylori IgG and IgA antibody levels. Statistical testing and analysis was performed by t-student and λ2 tests.
Results: Mean age of the women and men and also other demographic characteristics except their profession showed no significant difference (P>0.05) in the two groups (PCOS and non PCOS). H.Pylori antibody IgG serum level was positive in 78% and 76.5% and H.Pylori antibody IgA level in 30.5% and 37% of PCOS versus non PCOS patients respectively which showed no statistically significant difference (P>0.05). There was also no significant difference between the H.Pylori antibodies levels in the spouses in the two groups (P>0.05).
Conclusion: This study showed no significant difference in serologic examination re-sults in PCOS versus non PCOS patients. The finding of high prevalence of H.Pylori IgG and IgA positive levels in both PCOS and non PCOS patients can be probably re-lated to the high prevalence of H.Pylori infection or exposure in Iranian population and therefore suggest an issue for further investigation.
