Showing 5 results for Soltanzadeh
A Soltanzadeh , ,
Volume 51, Issue 2 (1 1993)
Abstract
Two hundred and twenty-eight patients who had developed Bell's palsy were investigated in a prospective study. Among them, 55% were male and 45% were female. The most common age of the disease onset was the third and beginning of the fourth decade of life. We found definite correlation between Bell's palsy, hypertension, and diabetes its recurrence rate was 9%. The most important complication was facial asymmetry that remained in 15% of the patients. The most common symptom prior to the development of facial palsy was the existence of pain in the back of ears and neck. Our patients responded well to 8 mg dexamethasone administered for a period of one week
A Soltanzadeh , Mda Javadian ,
Volume 55, Issue 1 (30 1997)
Abstract
Botulinum toxin produced by Clostridium butolinum in one of the most fatal toxins known. Botulism is the name given to condition produced by this toxin. In recent years the diluted form of this toxin has been produced in injection form and used for treatment of hemifacial spasm and blepharospasm. This toxin blocks neuromuscular junction and inhibits acetylcholine release. In this article we reported 36 patients suffering from hemifacial & blepharospasm treated by injections of botulinum A toxin. 85 to 90 percent of patients responded well. The common complications of this drug were ptosis, hemifacial paresis, burning of the mouth and discoloration of the injection site. Generally speaking the patients preferred this toxin to taking oral medications which were less effective.
A Soltanzadeh ,
Volume 55, Issue 5 (1 1997)
Abstract
In this research we tried to study frequency of clinical manifestations in Parkinson's disease. Hence, a prospective study was conducted in 317 patients who were affected by Parkinson's disease. In a questionnaire we collected data of patient's age, gender and signs and symptoms and then analyzed them. The most common features in our patients were tremor and muscular rigidity. Olfactory dysfunction was observed in 61% of our patients. Dysarthria, stooped posture, fixed facial expression, intellectual deterioration and the on-off response had various frequency among the patients. A new and important point in our research was considerable frequency of Anosmia or Hyposmia in spite of it's low prevalence among the patients of previous studies.
A Soltanzadeh , A Javadian ,
Volume 55, Issue 6 (1 1997)
Abstract
Twenty cases of isolated optic neuritis (15 female, 5 male) were studied and followed for several months to years after the initial attack. The mean age of patients was 23 years (range: 15-29 years). The most frequent clinical manifestations were decreased visual acuity and blurred vision. A complete neurological examination was performed. In 15 cases (75%) the initial brain MRI was abnormal. In fourteen cases, other signs of multiple sclerosis presented in one month to eight years following the initial attack of optic neuritis eleven of the latter cases had an abnormal initial MRI. Acute optic neuritis can be considered a presenting feature of multiple sclerosis, particulary in the presence of an abnormal brain MRI.
Kahnouji H, Soltanzadeh A, Sedighi N, Monshi B, Yousefi N, Alaleh A,
Volume 65, Issue 10 (2 2008)
Abstract
Background: Recent studies have raised the issue of an increased incidence of polycystic ovaries (PCO) and menstrual disturbances in women with epilepsy treated with valproate (VPA). It seems that antiepileptic drugs, especially valproate, may have a functional role in altering the endocrine system of child-bearing women with epilepsy. We conducted this study to investigate the association of VPA and ovarian structural/menstrual disorders in epileptic women.
Methods: In this cross-sectional study, we compared a total of 64 epileptic patients, aged 16-45 years, 32 of whom had been taking VPA alone and 32 were on other antiepileptic drugs for a minimum duration of six months. Ovarian sonography was performed and body mass index (BMI) calculated for all subjects. We also recorded the presence of menstrual disturbances in both groups.
Results: Fifteen (46%) of the VPA subjects had PCO compared to 7 (21.9%) of the other group. In the VPA group, four (12.5%) had oligomenorrhea, one (3.1%) amenorrhea and 13 (40.6%) had irregular menstrual cycles. However, from the other group, two (6.3%) subjects had oligomenorrhea and seven (21.9%) had irregular menstrual cycles amenorrhea was not present in the non-VPA treated patients. Mean BMI was 22.5 kg/m2 among the VPA subjects and 20.1 kg/m2 in the non-VPA subjects.
Conclusions: This study supports the association of PCO and high BMI with VPA treatment. The frequency of menstrual disturbances did not differ significantly between the two groups.
