Showing 5 results for Tabari
Rabiei Hashemi Sm, Tabari M,
Volume 59, Issue 1 (7 2001)
Abstract
Pilonidal disease affects mostly young men during work and educating years and bears a host of complications. After excision of the pilonidal sinus, some surgeons leave the wound open (secondary healing) and others close the wound primarily. The aim of this study is to compare mean duration of stay, length of operative procedure, length of time to return to work, wound infection rate, recurrence rate, the residual scar, the amount of pain endured, number of dressings required after the procedure and the amount of time required for complete healing in pilonidal sinus patients undergoing each of the above procedures. Fifty patients with chronic pilonidal sinus were randomly chosen to undergo one of these surgical procedures. One-half were treated by surgical excision and fasciocutaneous flap (Group A), the other half were treated with surgical excision and secondary healing (Group B). All the patients were followed up during a six month interval. No cases of infection or recurrence were seen. Although group A patients had significantly longer hospital duration of stay and the procedure performed was more time consuming, compared to those of group B (P<0.001), but in this group of patients (Group A), the length of time to return to work, the residual surgical scar, the amount of pain and the number of postoperation dressings and the time required for complete healing were significantly less than group B patients (P<0.001). Considering the lesser complication rates observed in group A patients, and in view of the youth and health of the majority of pilonidal sinus patient which renders them tolerant to the lenghtly procedure, the performance of the fasciocutaneous flap procedure is not only more cost effective but also results in more rapid return to work and greater patients satisfaction. This procedure is strongly recommended to other colleagues in this regard.
Vahid Dastjerdi M, Alavi Tabari N, Asgari Z, Beygi A,
Volume 65, Issue 11 (1 2008)
Abstract
Background: Post-menopausal hemorrhage is one of the most common complains in gynecologic clinics. More than 60% of these cases have abnormal findings in diagnostic work ups. There is contraversy about the best diagnostic method for evaluating post-menopausal hemorrhage. The aim of this study was to evaluate the results of Trans-Vaginal Ultrasonography and compare its result to ones derived from direct endometrial biopsy and Hysteroscopy findings.
Methods: In a cross-sectional study, menopausal women who attended the outpatient clinic of Arash Hospital, Tehran University of medical Sciences, from April 2005 to March 2006 with the complain of hemorrhage were evaluated. In all of these patients, after getting informed consent, Trans-Vaginal Ultrasonography, Dilatation and Curettage and Hysteroscopy were performed.
Results: The total number of 90 women was recruited to the study with the age range of 41-80 years. The mean age of participants was 53.84 ± 6 years and 4.3 ± 5.1 years had passed from their menopause. The mean thickness of endometrium, measured by Trans Vaginal ultrasonography was 6.25 ± 3.7 millimeter. In the biopsy derived specimens, the most finding pathological presentation was atrophy (48.9%) and the Proliferative endometrium had the second prevalence (36.7%). Atrophy (44.4%) and Proliferative endometrium (33.3%) were the most prevalent finding in Hysteroscopy. There was a significant difference in endometrial thickness between groups of different pathological findings. A significant difference in endometrial thickness was also seen between groups with different Hysteroscopic finding. By grouping the data according to endometrial thickness, it became evident that endometrial thickness can predict the outcome of endometrial biopsy and Hysteroscopic finding efficiently. We used ROC curves to find the best grouping threshold for endometrial thickness to achieve the best sensitivity and specificity.
Conclusion: Measuring the endometrial thickness by Trans-Vaginal Ultrasonography is an appropriate non-invasive test for screening post-menopausal hemorrhage.
Haleh Akhavan Niaki, Reza Tabaripour, Mohammad Reza Esmaeeli Douki, Mandana Azizi, Javad Tavakoli Bazzaz, Bagher Larijani,
Volume 68, Issue 1 (4 2010)
Abstract
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Background: Cystic
fibrosis is a monogenic recessive disorder founds predominantly in caucasian
population causes exocrine glands function defect. This disease arises from
mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
Because of heterogeneity of the mutations in CFTR gene, phenotypic symptoms in
this disease are very variable. In this study we consider poly T polymorphism (T5, T7, T9) in the intron 8 of CFTR gene in normal individuals and cystic fibrosis
patients in mazandaran province.
Methods: Forty cases of cystic fibrosis patients and 40 normal
individuals were screened for poly T polymorphism in intron 8 of CFTR gene using
Reverse Dot Blot method.
Results: T7 allele is the most prevalent in normal individuals
and CF
patients and it's abundance is approximately 75%. T9 and T5 represent
approximately 20% and 5% of normal or mutant alleles respectively. T7/T7 genotypes in normal individuals and CF patients are the most prevalent with 72.5% and 60% prevalence rate,
respectively. T5/T9 and T5/T5 genotypes were not found. 22.5% of normal
individuals and 30% of CF patients had heterozygote genotypes.
Conclusion: The abundance of T5, T7, T9 alleles and the presence of 22.5-30% heterozygote genotypes in normal individuals and CF patients indicates
that poly T
polymorphism in intron 8 of
CFTR
gene can be used as a marker for detection of normal and mutant alleles in
prenatal diagnosis or can be used in carrier assessment in families with
previous history of the disease.
Kholghi Oskooei Vahid , Esmaeeli Douki Mohammad Reza, Tabaripour Reza , Pourbagher Roghieh, Tavakkoly Bazzaz Javad , Larijani Bagher , Akhavan-Niaki Haleh ,
Volume 69, Issue 12 (5 2012)
Abstract
Background: Cystic fibrosis (CF) is a multiorgan autosomal recessive disorder. As CF is highly heterogeneous in Iran and many mutations have a low frequency, routine molecular diagnostic methods are not very efficient. The use of highly polymorphic intragenic markers not only can facilitate phenotype prediction in prenatal diagnosis by gene tracking, but also can lead to the demonstration of possible associations between haplotypes and specific mutations. We determined IVS8 polyT and M470V polymorphisms in exon 10 of CFTR gene in this case-control study.
Methods: Polymorphisms of IVS8 polyT in 53 patients with CF were referred to Amirkola children's Hospital of Babol University of Medical Sciences, 2007 to 2011 and 49 fertile healthy individuals were determined by reverse dot blot method. M470V polymorphism was analyzed by PCR-RFLP.
Results: In IVS8 polyT study, T7 was the most frequent allele in healthy individuals than patients with CF (respectively, 82.8% Vs. 77.2%). T9 was more abundant in patients with CF than normal individuals (respectively, 21.7% Vs. 7.4%, P=0.005). T9/T9 genotype was more frequent in patients than healthy individuals (respectively, 15.1% and 2%, P=0.032). Study for M470V polymorphism showed that M/V was the most common genotype in normal individuals and patients with CF (respectively, 49% and 40.4%). M-T9 haplotype was highly associated with the disease in both patients with CF and normal individuals (respectively, 19.1% and 2.4%, (P<0.001)
Conclusion: The allelic distribution and heterozygosity results suggest that both M470V and IVS8 polyT can be helpful in the prenatal diagnosis of CF in Northern Iranians with a positive family history of the disease.
Masoomeh Tabari , Marjaneh Farazestanian, Helena Azimi, Maryam Esmaeilpour, Malihe Hasanzadeh Mofrad ,
Volume 79, Issue 9 (December 2021)
Abstract
Today surgery is supposed as the cure for many diseases and the fear of post-operation pain burdens stress over the patients. Postoperative pain can, especially if severe, complicate the patient's condition and may lead to chronic postoperative pain. post-operation pain control is effective in the recovery process, hospitalization period and patients’ satisfaction. Insufficient post-operation pain control increases complications and care costs. Local analgesia is one of the components of multimodal postoperative. analgesic protocol to control pain. Local analgesia technique is a simple, accessible and feasible method for various surgeries. The opioid analgesics to control post-operation pain are associated with some complications such as opium addiction, nausea and vomiting, late return of bowel function and social costs. This review study aims. to review previous studies on the effect of injection of analgesic agents in the surgical incision in post-operation pain control. This is a Narrative review study. to related scientific documentaries a search was conducted in Persian and English using the keywords of local injection of the incision site, wound infiltration with analgesic agents and post-operation pain control in Google scholar, PubMed and Scopus database during the years 2000 to 2020. The obtained articles included systematic reviews, Meta-analyses and randomized clinical trials (RCT). We reviewed studies that had utilized single-dose injection of analgesic agents in surgical incisions at the end of surgery to control post-operation pain. A total of ten studies were reviewed. There were 4 studies in the field of laparoscopic gynecological and non-gynecological surgeries, three studies in the field of laparotomy and three review studies. injection of analgesic agents in the surgical incision to control post-operation pain is easily available and does not necessitate any special skill. On the other hand, it is a safe method without further complications and does not increase the duration of surgery. Regardless of the differences in various studies and the kind of analgesic agents, a general reduction in pain severity and consumption of opioid and non-opioid analgesic agents were observed using the injection of analgesic agents in surgical site incision.
