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Showing 2 results for Abo Blood-Group System
Association between ABO blood group and hepatitis B and C infection
Mansour Bahardoust, Marjan Mokhtare , Shahram Agah ,
Volume 77, Issue 5 (8-2019)
Abstract
Background: Hepatitis is among the major health problems, especially in developing countries. During past decades, the association between type of blood group (ABO) and hepatitis B and C virus has always been discussed. This study was designed to investigate the possible association between type of ABO blood group and chronic hepatitis B and C infection.
Methods: In the present analytical study, frequency of blood groups and their relationship with hepatitis B and C were evaluated in three groups: group A (patients with hepatitis B), group B (patients with hepatitis C) and group control (subjects with non-hepatitis B and C). The study was done from October 2016 to October 2018 on patients who referred to Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. Demographic and laboratory data of all participants were extracted and collected from their medical records.
Results: Overall, 196 and 103 patients in group A, B and three hundred control were included in this study, respectively. The baseline demographic data of patients were not significantly different between treatment groups. The mean age of participants was 35.1±13 years. The O blood group was significantly higher in patients with hepatitis B (46.4%) and hepatitis C (41.9%) compared to control group (34%) (P=0.001). The risk of hepatitis B and C infection were significantly higher among patients with O blood group (OR = 3.9, 95% CI 2.1-5.9; P = 0.001) and (OR = 2.7, 95% CI 1.7-5.6; P = 0.02), respectively] while, the risk of hepatitis B infection was significantly lesser in participants with blood group A (OR = 0.4, 95% CI -1.2-0.8). Rh positive participants significantly were at higher risk of hepatitis (B and C) than Rh negative participants. (P<0.05).
Conclusion: Participants with blood group O were at higher risk for chronic hepatitis B and C B infection and antigen (Rh) positive. Hepatitis B infection was reported lesser in participants with blood group A.

Evaluation of the relationship between blood group and intubation and mortality rate in COVID 19patients.
Faranak Behnaz, Azita Chegini, Sogol Asgari,
Volume 80, Issue 3 (6-2022)
Abstract
Background: Coronavirus (COVID-19) represents a global public health crisis that is causing significant deaths and affecting health systems around the world. There are several risk factors for the severity of infection, complications and mortality of COVID-19. One of them is blood group. The aim of this study was to investigate the relationship between blood group and rate of covid 19 disease.
Methods: A cross sectional study was performed on 130 patients over 18 years of age admitted in ICU of Shohada Tajrish Hospital between August 2020 and April 2021.The positive COVID-19 diagnosis was confirmed by polymerase chain reaction (PCR) test. Blood groups were determined and then, we monitored and followed up the patients' outcome during staying in ICU, the need for intubation, recovery and death. Data were collected using a questionnaire and analyzed by Pearson correlation coefficient and stepwise multiple regression analysis. Results were determined based on Fisher’s exact test. P<0.05 was considered significant.
Results: 60 (46.1%) patients had blood type A, (20%) 26 patients blood type AB, 12 (9.2%) patients’ blood type B and (24.7%) 32 patients blood type O. Blood group A was significantly higher in these patients. 55 patients (42.3%) were female and 75 patients (57.7%) were male. Their mean age was 43.19±19.05. Totally, 43.1% of hospitalized patients were intubated regardless of blood type. The number of cases requiring intubation was higher in people with positive blood type A. The lowest need for intubation was seen in blood type B negative. Blood group A positive (39.6%) and then AB negative (33.3%) had the highest mortality rate. Death was not observed in blood group A negative, B negative, B positive and O negative.
Conclusion: The number of patients with COVID-19 with blood type A was significantly higher (46.1%). The most common blood group in these patients was A and the lowest was blood group B. The number of cases requiring intubation was higher in people with positive blood type A.

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