Showing 4 results for Cabg
Mir Khani Sh, Foroozan Nia S.kh,
Volume 58, Issue 4 (7-2000)
Abstract
The most common cardiovascular surgery in the world and Iran as well, is CABG. One of the most important post-operative complication of this operation, that increase morbidity and mortality, is peri-operative MI. Incidence of peri-operative MI in CABG operations is between 2.5 to 5.5%. In this study we determined the prevalence and incremental risk factors of peri-operative MI in 300 consequative CABG operation, in the Imam Khomeini hospital. Diagnostic criteria for peri-operative MI were positive ECG finding (New and persistent Q.wave) and positive CPK-MB (Serum level>100 unit) at 3 different time: 1) Just before operation in the ward, 2) Just after operation in the ICU, 3) First post-operation day (At 8 A.M). In 300 patients positive ECG findings were seen in 7% (21 cases), positive CPK-MB was 12.7% (38 cases) and both of them were positive in 5% (15 cases). Therefore the prevalence of peri-operation MI was 5% (15 cases). Incremental risk factors in the patients with peri-operative MI were history of diabetes mellitus, hypertension, hyperlipidemia, left main disease, and endarterctomy. Therefore because of high incidence of peri-operative MI in CABG operation we should try to change the risk factors and decrease the prevalence of this complication.
Forouzan-Nia S.k, Abdollahi M.h , Motafakker M , Dehghan Hr , Rajabiun H ,
Volume 64, Issue 7 (8-2006)
Abstract
Background: Atrial fibrillation is the most common arrhythmia following CABG. This complication can cause palpitation, significant hemodynamic instability and thromboembolic events. This prospective randomized study evaluate prophylactic effects of propranolol low dose amiodarone and high dose amiodarone in patients candidate for CABG.
Methods: Three hundred consecutive patients undergoing elective CABG were randomly categorized into three groups (each group contains 100 patients). Patients in group1 (control group) received 10mg/TDS propranolol per oral (P.o), preoperatively. Patients in group 2 received 10mg propranolol TDS, P.o plus 350mg/24h amiodarone. Patients in group 3 received 10mg propranolol TDS P.o plus 1000mg/24h amiodarone 24 hours before operation.
Results: Atrial fibrillation occurred in 12 patients (12%) in group 1, four patients (4%) in group 2 and 10 patients (10%) (P=0.035) in group 3. AF occurred in 10.36% of men and 3.84% of women. There was no AF in off- pump groups and 9.73% in on-pump groups
Conclusion: This study suggested the combination of propranolol plus low dose amiodarone for post CABG atrial fibrillation prophylaxy.
Abdollahi M.h, Forouzan S.kh, Zahreh S,
Volume 64, Issue 10 (10-2006)
Abstract
Background: According to some previous reports prevalence of addiction estimated to be 3٪ in Iran. One of the most important key points about addiction is the identification of predisposing factors for starting substance use. False general believes can play important roles in this regard. This study evaluated the demographic characteristics of opioids addiction and the visions of them about the effect of opioids on their cardiac diseases.
Methods: This cross-sectional analytical study intended to evaluate situation of opiate dependency among 1329 CABG patients in Yazd Afshar hospital based on criteria of the diagnostic and statistical manual of mental disorders, Fourth edition (DSM-IV).Data were collected from each subject by a self report questionnaire and structured interview and was analyzed using chi-square and ANOVA and MC nemar test. P<0.05 was determined significant.
Results: The data were gathered from 1329 CABG patients (945 men and 384 women). In addition 131 patients (9.9%) containing 127 men (98.9%) and 4 women (1.1%) were opium dependent based on DSM-IV criteria. Mean age of opium dependent group was significantly higher than non-dependent patients (58.5 ± 10.08 VS 50.7 ± 10.15) (P= 0.000). Opium was the most common used substance (96.9%) and inhalation was the preferred pattern of use (52.7%). Majority of addicted patients were simple workers (44%). Based on educational levels, 57.2% of opium dependents have had primary education (under high school). Eighty two (62.5%) of addicted groups believed that after starting opium, their cardiovascular function and chest pain had been improved. Although before starting opium use 58 (44.6%) of them have had this belief
Conclusion: The prevalence of opium addiction in CABG patients is relatively high, and the majority of addicted patients are on this belief that opiates have positive effects on improvement of their chest pain and cardiovascular function. Because the effects of opioids on chest pain are palliative, the necessity of education for correction of this idea has been identified.
Tanaray B, Eslami M, Salehi M, Jahanzad I, Emami M,
Volume 68, Issue 7 (10-2010)
Abstract
Background: Studies of the association between post operative AF and Plasma level of NT- Pro BNP have reported conflicting findings. The aim of the present study was evaluation of the association between post coronary bypass graft- Atrial Fibrillation (AF) and Plasma level of NT- ProBNP as an independent risk factor of AF development in patients undergoing coronary artery bypass graft.
Methods: In a cohort study, 79 patients with sinus rhythm who admitted in Imam Khomeini Hospital in Tehran, Iran, during February 2009 and February 2010 for CABG are included the study and followed for developing post operative AF rhythm.
Results: Post operative AF was found in 17.7% of patients. The peak time from the operation to the first AF episode was in second post op day in ten patients (71.4%). The serum level of ProBNP in patients with AF was significantly higher (1624± 647 versus 221± 238 pg/ml, p< 0/0001). Increased age, Increased LA size and high plasma level of ProBNP were associated with increased risk for post op AF. After adjustment of risk factors, plasma level of ProBNP was the most important risk factor with odds ratio of 15.34 with CI 95% 1.77-132.95 and then LA diameter with odds ratio of 6.11 with CI 95% 0.99-37.42 was independently correlated with post op AF. Correlation between plasma level of ProBNP with age and LA size was seen too (LA size r = 0.0281, p= 0.012). Between age and ProBNP (r= 0.337, p= 0.002). The best cut off point for plasma ProBNP as a predictor of post op AF was 854 pg/ml.
Conclusion: Increased level of preoperative ProBNP levels could be an independent predictor of post operative Atrial Fibrillation.
