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Background: The
aim of this study was to evaluate the mid-term outcomes of concurrent total correction of
Tetralogy of Fallot (TOF) after pulmonary valve (PV) replacement and its relation to QRS duration and MRI results.
Methods: In
this study, 51 patients with TOF who
had the TOF surgery and PV
replacement enrolled the study. Demographic data, MRI
results such as, right ventricular end diastolic volume, right ventricular end
systolic volume, systolic and diastolic indexes noted. Moreover, QRS
duration and the patients' cardiac functional class were evaluated immediately
before and 6 months after the surgery.
Results: From
51
patients, 27.5% were female and 72.5%
were male. The mean age of participants was 23.48 (SD=5.82)
years. Functional class changes were statistically different (P<0.001)
comparing the status before and after the surgery. The mean QRS
duration before surgery was 130.20 (SD=16.89) ms
which was in significant contrast with post-surgical states, 122.45
(SD=16.90) ms (P<0.001). Mean QRS
duration before and after surgery was statistically lower in asymptomatic
patients (P=0.028 and P=0.025,
respectively). There was a statistical relationship between pre-surgical
systolic and diastolic indexes to post-surgical functional class as
asymptomatic patients had lower systolic and diastolic indexes (P=0.005 and
P=0.028,
respectively).
Conclusion: This study demonstrated
that QRS duration before and after
surgery can be an indicator to evaluate the cardiac function after surgery for
Tetralogy of Fallot. Moreover, systolic and diastolic indexes are factors
affecting the good prognosis of patients therefore, PVR surgery needs to be done
before the deterioration of systolic and diastolic indexes and cardiomegaly.