Nasirian A,
Volume 59, Issue 1 (4-2001)
Abstract
In the past ten years, 45 cases of infantile spasm treated in our center. From these patients, 15 cases received only steroid, other 15 cases only clonazepam, and the rest, a combination of clonazepam and steroid. All patients were observed for two years. This is a retrospective study, the data being extracted from patients' record. A number of patients were treated in ambulatory and the others were patients of the hospital. The result of comparison of optimal control of seizures are as follow: 1) In "only steroid group" 27 percent of the patients were free of seizure, 2) In "only clonazepam group" 28 percent showed no seizure, 3) in "combined clonazepam and steroid group" 39% were seizure-free. Based on this trial we believe that treatment of infantile spasm with combined steroid and clonazepam is better than any of them alone. Considering these results, we believe that the treatment of infantile spasm with a combination of steroid and clonazepam is preferable to these drugs.
Reza Saeidi, Mahin Tafazoli, Mahbobeh Gholami Robatsangi,
Volume 67, Issue 12 (3-2010)
Abstract
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Background: Infantile colic has been defined as episodes of
excessive and persistent crying without known medical cause. Kangaroo
mother care is a new method for baby care with several advantages. A
universally available and biologically sound method of care for all newborns,
with three components: skin-to-skin contact, exclusive breastfeeding, support
to the mother-infant dyad. This study designed
for evaluating Kangaroo mother care
on infantile colic.
Methods: This study was a randomized controlled trial. From
1th may 2008
to 1 may 2009
a total of 70 children, aged 3-12
weeks with persistent colic symptoms were studied. The
children were referred to Sheikh clinic, Mashhad,
Iran,
because of excessive crying. Normal mother-infant
pairs were recruited at 3 to 12
weeks of age after obtaining baseline for two days. Subjects
divided randomly to kangaroo care or conventional care group and mothers in
both groups filled diary for seven days.
Results: In the beginning of the study, the infants in kangaroo
care group had 3.5 hr/d crying and after
the intervention, it decreased to 1.7 hr/d,
the difference were significant (p<0.05).
But there were no difference in feeding duration
between two groups (p=0.2).
Awake and content (normal
behavior) behaviors were
significantly increased in the kangaroo care group (p=0.001).
Sleep duration was significantly increased in
the kangaroo care group (p=0.02).
Conclusions: Kangaroo
care may be used as a simple and safe method for treatment of infantile colic.
