Showing 4 results for Preterm Birth
Moghadami N, Aminikhah B, Davari Tanha F,
Volume 67, Issue 3 (6-2009)
Abstract
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B ackground: Preterm birth which is
defined as delivery before 37 completed weeks was implicated in approximately two
thirds of neonatal death. Also preterm labors are the most common cause of
mortality and morbidity of infants in recent years and it costs high prices for
health system. We evaluate the relationship between prepregnancy maternal body
mass Index (BMI) and spontaneous and indicated preterm birth.
Methods: This study included 250 healthy pregnant
women, without any risk factors of preterm birth, were classified into
categories that were based on their body mass index. Association between BMI, weight gain and rout
of delivery were examined. Rates of indicated and spontaneous preterm birth
were compared.
Results: Obese women delivered
at a more advanced gestational age. (38/34±1/66 weeks vs 37/61±2/44, p=0/006). Obese patients had
significantly lower incidence of spontaneous preterm birth at < 37 weeks of gestation (16/8% vs 31/2% p=0/008). Obese women had
larger infants (3354/95±596/75 vs 311.24±558/357 p=0/001), and had more
frequent cesarean delivery (69/6% vs 52/8%, p=0/006). Weight gain during
pregnancy is poorly correlated with prepregnancy BMI (14/41±7/93 kg vs 13/78±4/94kg, p=0/4) and preterm birth.
Conclusion: In
this survey, there was adverse correlation between body mass index (BMI) before
pregnancy and preterm labor less than 37 completed weeks and we suggest more study for
evaluation between spontaneous and induced preterm labor mechanism and in obese and non obese women. However according to
this survey obesity before pregnancy is associated with a lower rate of
spontaneous preterm birth.
Marsosi V, Mashhadian M, Ziaei S, Faghihzadeh S,
Volume 67, Issue 11 (2-2010)
Abstract
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Background: Preterm delivery is a relevant public health problem since it is an
important factor determinant of morbidity and the main reason for neonatal
mortality. Many publications have pointed at clinical methods, biological,
biochemical and ultrasonographic markers, which applied in combination or on
their own, aim at predicting spontaneous preterm delivery. Transvaginal
sonography is an effective method for the study of uterine cervix during
pregnancy since it permits to assess the cervical morphology and biometry in
detail with a high degree of reliability. The aim of this study
was to evaluate the association between spontaneous preterm delivery (SPTD) before 35 and 37 weeks of gestational age, in high risk population and the measurement of
the cervix length and cervical funneling.
Methods: A prospective cohort of 200 women carrying high
risk pregnancies were evaluated by transvaginal sonography between 14th and 28th weeks of gestation.
Results: Cervical length less than 18mm before 35th and 37th weeks of gestational age and the presence
of cervical funneling presented a satistically significant association with
spontaneous preterm delivery before 35 weeks. The cervical length with less 18 mm demonstrated a strong association with SPTD before 37 weeks (p<0.005 OR=92.15) and before 35 weeks' gestation (p<0.001 OR=32.33). The logistic regression analysis suggested the
cervical length with less than 18mm as the only variable that revealed satistically significance association
with SPTD.
Conclusion: The results seem to indicate
that the assessment of cervical length is an important ultrasound marker for
predicting spontaneous preterm delivery.
Mashhadian M, Marsosi V, Ziaei S, Asghari Jafar Abadi M,
Volume 68, Issue 10 (1-2011)
Abstract
Background: Preterm delivery is a relevant public health problem. The aim of this study was
to evaluate the association between spontaneous preterm delivery (SPTD)
before 35 and 37
weeks of gestational age and the measurement of the cervix length, cervical
funneling and Cervical Gland Area (CGA),
in high risk pregnant population.
Methods: A prospective cohort of 200
women carrying high risk pregnancies was evaluated by transvaginal
sonography between 14th and 28th gestational weeks. The data were analyzed using statistical methods.
A multiple linear regression model was estimated
in order to examine the relationship between the gestational age at delivery
and the cervical markers. A multiple logistic
regression was estimated in order to analyze the factors associated to
spontaneous preterm delivery and the transvaginal sonographic markers.
Results: Cervical length less than 18 mm and the presence
of cervical funneling presented a statistically significant association with
spontaneous preterm delivery before 35 weeks.
The nondetection of Cervical Gland Area demonstrated a strong association with
spontaneous preterm delivery before (p=0.0001,
OR=169.1, CI=2.6-3.1) and 35th and 37th gestational week (p=0.001, OR=115,
CI=2.12-3.5). The multiple logistic regression
analysis suggested the non-detection of CGA as
the only variable to reveal statistically significance association with
spontaneous preterm delivery.
Conclusion: Based on results of present study the absence of
cervical gland area (CGA) can be a new and important ultrasound marker for predicting spontaneous
preterm delivery and needs to confirm with future multicenter investigations.
Roshan Nikbakht , Sara Masihi , Elham Pourmatroud , Afarin Rasti ,
Volume 72, Issue 10 (1-2015)
Abstract
Background: Preterm premature rupture of membranes (PPROM) occurs in 17% of pregnancies, which leads to 20% of perinatal death. According to previous studies uterine anomalies are one of the risk factors for preterm birth, PPROM and pregnancies complications. The aim of this study was to evaluate the relationship between PPROM and rupture of membrane (ROM) with uterine cavity anomalies based on hysteroscopic findings.
Methods: This cross-sectional study was conducted in Imam Khomeini Hospital, Ahvaz, Iran, from May 2011 to May 2012. After conducting a pilot study, 66 nulliparous pregnant women at 14-37 weeks of pregnancy with PPROM and ROM were selected randomly. Then the women were evaluated by hysteroscopy at least six weeks after delivery or miscarriage. The control group includes 66 women with at least one normal pregnancy (without history of PPROM, secondary infertility or recurrent abortion), who underwent diagnostic or therapeutic hysteroscopy for other reasons than PPROM. The hysteroscope instrument specifications were KARL STORZ model (KARL STORZ GmbH & Co. KG, Tuttlingen, Germany), inner sheet 26153 BI, outer sheet 26153 BO, and BA lens with 30 degree. Normal saline solution (Sodium Chloride 0.9%) also was applied as distention medium. The study was approved by Ethic Committee of Ahvaz Jundihspur University of Medical Sciences. Informed consent was obtained for all participants.
Results: Overall, the frequency of uterine anomalies in case and control groups was 12.12% and 3%, respectively (P<0.05 based on Chi-square test). Possibility of uterine cavity anomalies in the women with preterm premature rupture of membranes (PPROM) was significantly higher than the women with normal pregnancy (OR=4.41, CI 95%: 0.9-21/63). About 3% of patients in the case group had undefined uterine anomalies. This anomaly was not in mentioned uterine anomalies classification of American fertility association. We did not observe such anomaly in control group.
Conclusion: In conclusion, we found that the possibility of occurring PPROM in women with uterine cavity anomaly was four-fold more than women without these anomalies. Hence, we recommend women with history of PPROM to undergo diagnostic hysteroscopy for detecting uterine anomalies before next pregnancy.
