Ehsani Ah, Noormohammadpoor P, Jamshidi S, Ghasemi H,
Volume 68, Issue 12 (3-2011)
Abstract
Background: Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP)
is a specific dermatosis of the third trimester of pregnancy,
commonly seen in primigravid women.
Case presentation: A 24-year-old
primigravida woman who had developed a rash immediately after delivery was
admitted to Razi Hospital
in Tehran, Iran. She had an erythematous
eruption, particularly concentrated on the abdominal striae with umbilical
sparing and involvement of limbs and extremities. Skin biopsy of the lesions on
the lower abdomen, showed superficial perivascular infiltrates with occasional
neutrophils and eosinophils. Both direct and indirect immunofloresence assays
were negative. The patient was ultimately treated with topical clobetasol
butyrate and oral chlorpheniramine for pruritus. Within a week, the lesions and
the itchings had disappeared completely.
Conclusion: Pruritic urticarial papules and plaques of
pregnancy are often, but not always, seen during the third trimester of
pregnancy, but sometimes they present in postpartum period without any prior
manifestations during pregnancy.
