Jangjoo A, Mehrabi Bahar M, Aliakbarian M,
Volume 67, Issue 5 (8-2009)
Abstract
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Background: Seroma
formation, or the subcutaneous collection of fluid, is a common problem after
surgery for the breast cancer. It may lead to wound-related complications and
also can delay adjuvant therapy. The aim of this study was to investigate the
effect of various clinical and therapeutic variables on seroma formation.
Methods: A prospective cross sectional study of patients who
underwent surgical therapy for breast cancer was carried out. Modified radical
mastectomy was performed on 67 patients (65%) and 28 patients (27.2%) underwent breast conservative surgery. Simple
extended mastectomy was done for the remaining 8 patients (7.8%). Seroma
formation was studied in relation to age, type of surgery, tumor size, nodal
involvement, preoperative chemotherapy, surgical instrument (electrocautery or
scalpel), use of pressure garment, and duration of drainage. All of the
patients followed for 4 weeks after surgery.
Results: A total of 103 patients with breast cancer were studied. The mean
age of the patients was 48.3 years (25-82). Seroma occurred in 27 (26.2%) patients. There was
statistically significant relation between age and seroma formation after
breast cancer surgery (p=0.005), while other factors studied was found to be
significantly ineffective. In addition, there was not any relation between
seroma formation and drain duration. However, two factors including type of the
operation and level of lymphatic dissection was considerable with confidence
interval up to 90%, but it was not statistically significant with
confidence interval >95% (p=0.068 and 0.063 respectively).
Conclusion: These findings suggest that the age is a predicting
factor for seroma formation in breast cancer patients, while other factors do
not significantly affect that.
Hamid Reza Hemmati , Mehdi Sadat-Hashemi , Raheb Ghorbani , Toraj Jafari ,
Volume 72, Issue 12 (3-2015)
Abstract
Background: Inguinal hernia is a common surgical problem which increases with aging especially in men. A common method for treatment is surgical repair using prosthesis, Lichtenstein technique. One frequent complication after inguinal herniorrhaphy is soft tissues seroma. There are several methods to prevent or to drain seroma. Some surgeons suggest the insertion of closed suction drainage system but others disagree.
Methods: In this clinical trial study, 42 patients who are candidate for hernia repairing (Lichtenstein technique), referred to Amir Al-Momenin Hospital in Semnan, Iran, from 2011 to 2012, were randomly divided into two groups. So that, the list of eligible patients in the study, were numbered, and then using the patients' code, patients, who assigned an odd number in the registration list, were allocated to group 1, the remainder were placed in group two. The two first numbers in registration list (1 or 2), were randomly assigned to groups. Group 1 underwent hernia surgery without closed suction drainage and the second group underwent hernia surgery with closed suction drainage. The patients were evaluated for seroma, hematoma or wound infection after 24 hours, during days 4 to 7 and days 10 to 15 following surgery.
Results: No adverse event including hematoma, seroma or wound infection occurred in either group with or without closed suction drainage in the first 10 days after surgery. Only one patient carried wound infection during days 10 to 15 following operation who was in the group with closed drainage (P=1.00).
Conclusion: In this study, Seroma and hematoma was not observed in patients with and without closed suction drainage. To avoid drains' complications, indiscriminate use of antibiotics, prolonged hospital stay, we do not recommend the use of drains in this type of surgery.
