B Jahangiry ,
Volume 57, Issue 2 (5-1999)
Abstract
We have compared the effects of fentanyl and pethidine in the treatment of postanaesthetic shivering. Fifty patients who were shivering after routine abdominal surgery were allocated randomly to receive fentanyl 75 µg and pethidine 25 mg. After 10 min, 23 patients in pethidine group and 22 patients in the fentanyl group had stopped shivering which was not significantly different in the two groups. We conclude that fentanyl 75 µg was effective in the treatment of postanaesthetic shivering.
Hoseinkhan Z, Behzadi M,
Volume 64, Issue 12 (11-2006)
Abstract
Background: Postoperative shivering is a common postoperative complication. The aim of this study was to compare the effects of morphine, pethidine and fentanyl in postoperative shivering control.
Methods: In this prospective, randomized, placebo-controlled, double-blinded, clinical trial, we enrolled 72 adults scheduled for elective surgery under general anesthesia at Imam Khomeini Hospital in 2003. All the patients were anesthetized in the same manner. After transferring the patients to the post-anesthesia care unit, shivering was noted and, in patients with a shivering score of one or more, morphine (2.5 mg), pethidine (25 mg), fentanyl (25 µg) or normal saline (all with a volume of 10 ml) was randomly administered intravenously by a two-minute injection. A second shivering score was recorded 10 minutes later.
Results: Pethidine and fentanyl were significantly more effective than normal saline, but there was no significant difference between normal saline and morphine groups. Pethidine was more effective than two other drugs in shivering control.
Conclusions: Pethidine was significantly more effective than two other drugs. Fentanyl decreases postoperative shivering less effectively than pethidine, but morphine had no effect on postoperative shivering with an effect comparable to normal saline.
