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Showing 2 results for Cancer Surgery
Seroma formation after breast cancer surgery: incidence and risk factors
Jangjoo A, Mehrabi Bahar M, Aliakbarian M,
Volume 67, Issue 5 (8-2009)
Abstract

Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: Seroma formation, or the subcutaneous collection of fluid, is a common problem after surgery for the breast cancer. It may lead to wound-related complications and also can delay adjuvant therapy. The aim of this study was to investigate the effect of various clinical and therapeutic variables on seroma formation.
Methods: A prospective cross sectional study of patients who underwent surgical therapy for breast cancer was carried out. Modified radical mastectomy was performed on 67 patients (65%) and 28 patients (27.2%) underwent breast conservative surgery. Simple extended mastectomy was done for the remaining 8 patients (7.8%). Seroma formation was studied in relation to age, type of surgery, tumor size, nodal involvement, preoperative chemotherapy, surgical instrument (electrocautery or scalpel), use of pressure garment, and duration of drainage. All of the patients followed for 4 weeks after surgery.
Results:  A total of 103 patients with breast cancer were studied. The mean age of the patients was 48.3 years (25-82). Seroma occurred in 27 (26.2%) patients. There was statistically significant relation between age and seroma formation after breast cancer surgery (p=0.005), while other factors studied was found to be significantly ineffective. In addition, there was not any relation between seroma formation and drain duration. However, two factors including type of the operation and level of lymphatic dissection was considerable with confidence interval up to 90%, but it was not statistically significant with confidence interval >95% (p=0.068 and 0.063 respectively).
Conclusion: These findings suggest that the age is a predicting factor for seroma formation in breast cancer patients, while other factors do not significantly affect that.


Surgical management of non-melanoma skin cancers with flap and graft reconstruction
Behzad Iranmanesh, Ali Morsali, Nazanin Zeinali Nezhad ,
Volume 83, Issue 2 (5-2025)
Abstract
Background: Non-melanoma skin cancers (NMSCs) are among the most prevalent malignancies globally. Investigating their characteristics and treatment-related outcomes can significantly contribute to optimizing management strategies including surgery, chemotherapy and radiotherapy. This study aimed to examine the characteristics of NMSCs and the complications following surgical treatment (such as necrosis and bleeding).
Methods: This is a retrospective descriptive cross-sectional study which was conducted to investigate the features of patients initially diagnosed with NMSC (confirmed by histopathological examination of the lesion) at dermatology ward of Afzalipour Hospital, Kerman University of Medical Sciences, between 2018 and 2021. Inclusion criteria were definitive diagnosis (based on the result of pathology) of an NMSC and undergoing surgical management. Exclusion criteria included incomplete patient records. Relevant data were extracted and recorded using a data collection form. Finally, all collected information was statistically analyzed according to the study objectives, and the overall frequency of NMSC surgeries, as well as their frequency based on study variables, was reported descriptively.
Results: A total of 37 NMSC surgeries were performed. The majority were basal cell carcinomas located on the face. Over half of the patients were male, and most had underlying medical conditions despite lacking common risk factors such as smoking and sun exposure. The most common flap techniques used were rotational flap, island pedicle flap, and H-plasty flap. Two complications were observed: one case of bleeding at the surgical site and one case of wound edge necrosis, both occurring one week post-operation.
Conclusion: In the southeastern region of Iran, NMSCs requiring surgical treatment showed a lower prevalence than anticipated. However, their pathological and demographic characteristics were consistent with global observations. The incidence of post-surgical complications was also low. Nevertheless, future studies with larger sample sizes in this region and across the country are recommended to enhance the reliability of these findings.

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