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Demographic and pathologic findings of squamous cell carcinoma of skin and lip in pathology department of Razi Hospital1
R Najafizadeh , F Gharibduost , A Khalvat ,
Volume 58, Issue 2 (5-2000)
Abstract
Squamous cell carcinoma, a cancer of keratinocytes origin, mostly involves sun-exposed areas of the skin. To study the pathologic and demographic features of this disease, records of 395 patients of squamous cell carcinoma of skin and lip were reviewed. Most of the patients (83%) aged 40 years or more at the time of diagnosis. Respectively, 74.4% and 75.8% of cases with skin and lower lip carcinoma were men, but in upper lip cases frequencies of both sexes were equal. The number of patients referred from western and north-western provinces were much more than those of other provinces of the country. The most frequent histologic stage was grade I (53% and 58.8% in skin and lip carcinoma, respectively), showing that most patients visit physicians early enough, and are diagnosed in early stages of the disease.
Intraocular Pressure And Its Determinants In Tehran Population
Kashi Ah, Fotouhil A, Hashemi H, Mohammadl K,
Volume 63, Issue 3 (6-2005)
Abstract

Background: The aim of this study was to provide data, on the distribution or intraocular pressure (IOP) in Tehran population.

Materials and Methods: Through a population-based, cross-sectional study, a total of 4565 Tehran citizens were studied in the Tehran Eye Study. The findings of the participants (n=3834) 10 years and older free of glaucoma diagnosis or suspicion who had undergone applanation tonometry examination are presented. All participants received a standardized protocol included applanation tonometry, and some other ocular measurements, fundus examination, demographic data and an interview. IOP measurement was used to evaluate its distribution by age, sex, and some eye parameters.   ‎

Results: Mean ± SO IOP was 14.5±2.6 in the total population, 14.4±2.7 in men, and 14.5±2.5 in women. Normal range (mean±2SD) of IOP was determined to be 9.3 - 19.7 mmHg. IOP increased significantly with age and cup-disc ratio except for a fall in old ages. This relationship was also observed when we analyzed individuals without diabetes or hypertension history. IOP increased with darker eye pigmentation except for blue/gray eyes. There was a non-linear ‎increase of IOP from emmetropic to high myopic eyes. ‎

Conclusion: Mean and/or normal range of IOP and their associations have been reported with wide differences in various studies. It is wise that studies evaluate IOP distribution or associations in healthy people and glaucoma people separately and also report the prevalence of IOP risk factors in their population to allow for a logical comparison of studies.


Spatial structure of breast cancer using Poisson generalized linear mixed model in Iran
Mansour Rezaei , Abdullah Jalilian , Behzad Mahaki , Maryam Veismoradi ,
Volume 77, Issue 3 (6-2019)
Abstract
Background: Breast cancer is one of the most common diseases in women and causes more deaths rather than other cancers. The increasing trend of breast cancer in Iran makes clear the need of extensive breast cancer research in this area. Some studies showed that in the variety countries and even in the different areas in one country has different risk of breast cancer incidence and this is a reason that there is a correlation between region of life and risk of breast cancer. The purpose of this study was to determine the spatial structure associated with the incidence of breast cancer based on statistical models and identification of areas with high incidence of breast cancer in Iran.
Methods: This ecological study was conducted in Kermanshah University of Medical Sciences, Iran, from February to July 2018. Data on breast cancer patients in all provinces of Iran (30 provinces) were investigated since 2004 to 2009. Risk factors in this study included fruit and vegetable consumption, physical activity, overweight or obesity, and human development index. In this study, we have used routine and spatial Poisson's generalized linear mixed models for data analysis.
Results: In both routine and spatial models, direct and significant correlation was found between the incidence of breast cancer and the human development index (P<0.05). In addition to human development index, overweight or obesity factors were also had direct and significant relationship to the incidence of breast cancer in the spatial Poisson's generalized linear mixed model (P<0.05). In the spatial Poisson's generalized linear mixed model with correlation structure of Besag Yorg Molie (BYM), two provinces of Gilan and East Azerbaijan had the highest risk of breast cancer incidence and province of Kohgiluyeh and Boyer Ahmad had the lowest risk of breast cancer incidence.
Conclusion: The results showed that the distribution of breast cancer incidence in Iran has a spatial structure. That is, the adjacent provinces have similar incidences of this disease.

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