Showing 6 results for Double
Talaiezadeh Ah, Noori M,
Volume 65, Issue 14 (3-2008)
Abstract
Background: Inguinal hernia accounts for about 80% of all hernias and are the most
common surgical procedure done in infants. There are different methods for repairing of
inguinal hernia such as tissue repair rate of recurrence by this method is 1-3%.
The purpose of this study was to introduce new method for this surgery and assessing
recurrence and complications.
Methods: This was a semi clinical trial. 174 patients were considered after five years.
(During 1998-2002). In this method after removing of hernia's sac, the floor of inguinal
canal was torn in two layers continuously. One of them was torn from cooper ligament to
fascia transversalis and the other one was torn from inguinal ligament to conjoint tendon
and finally the fascia of external muscle was torn on spermatic cord. The patients were
assessed by a questionnaire composed of two sections one about the site of inguinal hernia
and age of patients and the other was composed of questions about complication and
recurrence of surgery. Data was compared to other conventional tissue repair using Z test.
Results: The mean age of patients were 28-48 years, 164(94%) were males and 10(5/7%)
were females, 59(34%) of patients had left inguinal hernia (56 male and 3 female), 92(52%)
had right inguinal hernia (88 male and 4 female) and 23(13%) had bilateral inguinal hernia
(20 male and 3 female). Two patients (1/1%) had recurrence two years after surgery and no
complication were seen after 5 years.
Conclusions: There were no significant difference between methods of surgery (1/1%
recurrence) and other conventional tissue repair methods (1-3% recurrence). More long
evaluation is required to recommend this fast and simple method for routine repair of
inguinal hernias.
Bahari A, Izadi Sh, Adibi P, Sanee-Moghadam E, Khosravi H, Shahraki T,
Volume 69, Issue 4 (7-2011)
Abstract
800x600 Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4
Background: With respect to the importance of hepatitis B
vaccination of high-risk groups such as prisoners, this study was performed to assess
the comparability of a short-course double-dose vaccination schedule with the
standard 3-dose schedule.
Methods : Within a randomized clinical trial, a short-course vaccination (at months 0
and 1) with 20
microgram (double-dose) doses of the vaccine was compared to the standard
method of hepatitis B vaccination (at
months 0, 1 and 6,
with 10-microgram doses) in 100
prisoners in Zahedan city in Iran in 2009.
We made sure the sera from all the individuals were negative for markers of
previous hepatitis B infection. Subsequently
serum from all the participants was tested for anti-HBs
antibody 1, 2 and 7
months after the first dose of vaccination.
Results : Seroconversion rates (HBsAb>10
mIU/ml) 1, 2
and 7 months after the first dose of vaccination
were similar in the routine (11%, 79% and 94%,
respectively) relative to the double-dose group (26%, 95% and
93 %, respectively). The mean values of anti-HBs
antibody titers were similar in the 1st and 2nd
months for the two groups but it was significantly higher (P=0.002)
in the routine dose (514 mIU/ml)
versus the double-dose group (130 mIU/mL),
in the 7th month.
Conclusion: Demonstrating
comparable results with the standard 3-dose
schedule, it seems that short-term double-dose vaccination for hepatitis B is
a safe and acceptable method for use in high-risk groups such as prisoners.
Tahmasebi Mn, Enayati B, Enayati B,
Volume 69, Issue 9 (12-2011)
Abstract
Background: Anterior cruciate ligament (ACL) reconstruction is a first choice treatment for ACL-deficient knees, and arthroscopic single-bundle reconstruction has been widely accepted around the world in this regard. Although, such single-bundle reconstructions result in sufficient knee stability in most cases, but some patients have not been satisfied with postsurgical results in both short-term and long term clinical studies. One of the reasons for these unsatisfactory results could be related to the fact that normal function of the native ACL has not been restored by the traditional ACL reconstruction which uses only a single-bundle graft. The natural ACL consists of a 3-dimensional structure with multibundle fascicles, which can be anatomically divided into 2 main bundles, the anteromedial (AM) and the posterolateral (PL) bundles named for the orientation of their tibial insertions. The purpose of the present study was to compare double-bundle and single-bundle ACL reconstruction.
Methods: Twenty-two patients with anterior cruciate ligament tear who were candidates for ACL reconstruction were enrolled in the study undertaken in Shariati Hospital from 2009 to 2010. Fourteen patients underwent single-bundle and 8 patients double-bundle ACL reconstruction. The patients were evaluated by arthrometer and physical examination in postoperation follow up visit at least 9 months after the operations.
Results: Four out of 14 patients with single-bundle reconstruction had knee joint translation greater than 5 mm but nobody had knee translation more than 5 mm in the double-bundle reconstruction group.
Conclusion: Double-bundle ACL reconstruction seems to be more stable than single-bundle ACL reconstruction.
Noyan Ashraf Ma, Hoseini Mr, Bannazadeh M,
Volume 70, Issue 8 (11-2012)
Abstract
Background: Lung separation is the basis of thoracic anesthesia, which is performed by different instruments. Checking probable malpositioning of tracheal tube needs fiberoptic bronchoscopy. The aim of this study was to compare respirator suggested compliance with fiberoptic findings in detecting major tracheal tube malpositioning.
Methods: A total of 256 patients undergoing thoracic surgery with double-lumen tracheal tube insertion in Imam Khomeini Hospital, Tehran, Iran, during 2010-11 were divided into three groups (n=86). We used left-sided double-lumen tube (DLT) for left or right-sided surgeries (groups 1 and 2), and right-sided DLT for left-sided surgeries (group 3). The position of the tubes was evaluated and compared using bag compliance versus fiberoptic bronchoscopy.
Results: The mean age of the study population was 44.7±13.4 (16-73) years, while 155 (59.9%) were male. The sensitivity, specificity, positive and negative predictive values, and the accuracy of bag compliance test for left-sided DLT in supine position were 40% (95% CI: 20-60%), 99% (95% CI: 96-99%), 84% (95% CI: 54-94%) 92% (95% CI: 88-95%) and 92% (95% CI: 87-95%), respectively. The above-mentioned variables for lateral decubitus position respectively were 27%, 98%, 76%, 89%, and 88%. Malpositioning was more prevalent in right-sided DLTs (P=0.02).
Conclusion: Based on the results of this study, and the high specificity, positive predictive value, and accuracy of bag compliance test, its use is encouraged as an alternative to fiberoptic bronchoscopy for checking DLT position, specially, in emergent surgeries or when fiberoptic bronchoscopy is unreachable due to lack of expertise or personnel.
Soror Roozafzay , Khadijeh Hekmat , Kobra Shojaei , Pourandokht Afshari , Mohammad Bahadoram ,
Volume 72, Issue 5 (8-2014)
Abstract
Background: Bacterial vaginosis (BV) is the most prevalent causes of abnormal secre-tion in women at fertility age. Also, Bacterial vaginosis is one of the most common dis-eases in women who refer to gynecology clinic. The main cause of the pathogenesis is increasing pH of vagina due to reduced number of lactobacillus and growth of anaero-bic bacteria. Prevalence of BV varies between 10 to 30 percent in different societies. Amsel criteria is used as diagnostic test in BV. This interventional study was designed to assess the impact of vaginal lactobacillus suppository and metronidazole compared to metronidazole alone on the recovery and recurrence of bacterial vaginosis.
Methods: This study was a prospective, randomized, double-blind clinical trial which was conducted on 130 women with bacterial vaginosis to compare the effects of vagi-nal lactobacillus suppository and metronidazole. Bacterial vaginosis was diagnosed us-ing Amsel criteria that based on some clinical symptoms. Patients were divided into two groups, first group were treated with oral metronidazole plus lactobacillus and second group were treated with metronidazole alone. Patients were followed-up one week and four weeks after initiation of the treatment.
Results: One hundred and thirty women completed the study. Patients were followed at one and four weeks after initiation of intervention. Amsel criteria and recovery rate in both groups compared before treatment one and four weeks after treatment. The crite-ria and treatment were significantly improved, but this improvement was higher and statistically significant in the metronidazole plus Lactobacillus group compared to sec-ond group (P< 0.0001).
Conclusion: The protective effects of lactobacillus in dealing with anaerobic patho-gens as well as the negative impact of metronidazole on lactobacillus of vaginal flora, use of lactobacillus along with metronidazole especially in patients with recurrent infec-tions is recommended. In other words, using lactobacillus with metronidazole for treatment of bacterial vaginosis is more effective than metronidazole alone.
Ali Hadi , Valiollah Mehrzad , Nazanin Vaziri , Lalaeh Shariati , Golnaz Vaseghi ,
Volume 78, Issue 2 (5-2020)
Abstract
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma (NHL), which is the most common type of lymphoma. NHL comprises a group of clinically and biologically diverse diseases, which range from indolent to aggressive clinical courses. Despite treatment advances in the last three decades with the use of combination immunotherapy, a significant fraction of patients relapses or are refractory to these treatments. Actually, there is no standard method for detection of recurrence. The purpose of this study was to evaluate the level of this enzyme in the patients with recurrent DLBCL compared to healthy controls.
Methods: In this randomized double-blind, placebo-controlled trial, the serum level of pyruvate dehydrogenase (PDH) enzyme in total of 26 patients with DLBCL recurrence in compare with 26 healthy individuals in the Sayed Al-Shohada Hospital, Isfahan University of Medical Sciences in Iran from September 2016 to September 2018, were assessed. The clinical data including age criteria, the Eastern Cooperative Oncology Group (ECOG) score rating, total bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), prothrombin time and international normalized ratio (PT/INR), CT-scan, serum creatinine, platelet count, the absolute number of neutrophils, and the interval until the last treatment were gathered. After obtaining informed consent, blood samples were taken. and the PDH enzyme was measured in case and control groups.
Results: Fifty-three percent of patients were male and the mean age of participants in case and control groups was 37.2±17.3 and 34.8±8.9, respectively. Subsequently, the PDH levels were measured according to the enzyme protocol. The levels of enzyme in patients with relapse were significantly lower than normal ones (P=0.0003). The PDH serum level was also evaluated by age and sex, which did not show any significant differences (P=0.86).
Conclusion: In patients with relapsing B-cell lymphoma, the pyruvate dehydrogenase (PDH) enzyme serum levels were significantly lower than healthy subjects, but this difference was not related to age and gender. In the case of further studies and comparisons beyond this study, this enzyme could be a good candidate, used as an alternative diagnosis tool, in patients with recurrent lymphoma.
