Ataei N, Safaian B, Madani A, Esfahani St, Ataei F,
Volume 67, Issue 2 (5-2009)
Abstract
Background: Early diagnosis of renal parenchymal involvement in children with acute
pyelonephritis (APN) using isotope scan and early treatment may decrease or prevent
development of renal parenchymal lesions. We designed this study to assess the
diagnostic value of certain biologic parameters in children with first- episode of acute
pyelonephritis (APN) documented by 99m Tc-dimercaptosuccinic acid (DMSA)
scintigraphy.
Methods: We compared the laboratory findings of leukocyte count, erythrocyte
sedimentation rate (ESR) and serum C-reactive protein (CRP) levels with the results of
the DMSA scans obtained within three days of admission. One hundred-two children (93
girls and 9 boys aged 1 month–12 years (mean 2.85±2.92 years) were enrolled in the
study. Of these patients, 203 renal units, were investigated using scintigraphy. Voiding
cystourethrography (VCUG) was performed in 98 children (195 renal unit) when urine
culture became negative.
Results: In all children one or both of kidneys had parenchymal involvement on
scintigraphy. Changes on the DMSA scan were found in 178(88%) renal units during the
acute phase. The extent of changes in DMSA scan were mild in 113/178(55.7%) renal
units, moderate in 40/178(19.7%) and severe in 25/178(12.3%). When inflammatory
markers were correlated with the development of the severe renal lesions, as assessed
with DMSA scan, a highly significant correlation with both ESR (p=0.007) and leukocyte
counts (p=0.02) were found.
conclusions: We conclude that the incidence of renal parenchymal involvement in
Iranian children with APN is very high. Although increased ESR and leucocytosis may
be valuable markers for determination of severe renal parenchymal involvement, but
these parameters and also CRP, were inadequate in distinguishing mild to moderate
renal parenchymal involvement.
Parviz Saleh , Kian Alipasandi, Mohammadamin Rezazadehsaatlou , Negar Azizi , Amin Abdi Raad ,
Volume 75, Issue 6 (9-2017)
Abstract
Background: Urinary tract infections are very common in patients with high blood pressure. Hypertensive patients experience an average of three times of urinary tract infection per year. Blood pressure control is very important for preventing complications and also for identifying high-risk groups. Since, there is no national related study in this regard, the present study was conducted to investigate the effect of chronic hypertension on the incidence and recurrence of urinary tract infections.
Methods: In this case-control study, the required data were collected from outpatient cases referring to Taleghani Hospital and Sina Hospital related to Tabriz University of Medical Sciences in Tabriz city, Iran. Data needed for the control group included patients accompanying patients who had no symptoms of urinary tract infection and with no history of blood pressure.
| Results: 60 patients with urinary tract infections were examined: 57 (47.5%) of the subjects were men and 63 (52.5%) women. There was a significant relationship between the rate of red blood cell deposition in the first hour and systolic blood pressure. There was no significant correlation between the numerical value of white blood cell count and systolic or diastolic blood pressure in the studied patients. |
Conclusion: According to the results of the present study, there was a significant difference in systolic blood pressure in patients ESR 1 hour (red blood cell deposition rate in the first hour) with hypertension in case and control groups. There was a significant correlation between the ESR of the first hour and systolic blood pressure in the study, so that with an increase in ESR 1h, the systolic blood pressure increased in the examined patients, however, no significant correlation was found between ESR 1hour and diastolic blood pressure. Also, there was no meaningful correlation between the numerical value of white blood cell count and systolic or diastolic blood pressure in the studied patients. There was no significant correlation between systolic and diastolic blood pressure and age.
