Showing 5 results for Gestational Age
Beigy A, Salavati J,
Volume 62, Issue 2 (5-2004)
Abstract
Background: The purpose of this study was to compare electronic fetal heart rate monitoring (EFM) characteristics between Appropriate for Gestational Age (AGA ) and Small for Gestational Age (SGA) fetuses and to determine whether SGA fetuses have specific abnormalities.
Materials and Methods: Among children born from Apr 2002 to Mar 2003 in Arash hospital, we identified 300 singleton infants born after 36 weeks' gestation of uncomplicated pregnancies in whom second-trimester (24-27 weeks' gestation) EFM records were obtained. Individual components of fetal heart rate (FHR) pattern baseline rate, baseline FHR variability, presence of acceleration and periodic and episodic deceleration , and birth characteristics were compared between AGA and SGA infants or between pregnancies with or without second-trimester decelerations. Statistical analysis was performed using Student t, Chi square and Fisher exact test.
Results: Among 300 infants, 261 (87%) were AGA and 39 (13%) were SGA 65 had and 235 did not have second-trimester decelerations. Baseline FHR variability, second- trimester decelerations and intrapartum FHR decelerations were significantly higher in SGA fetuses than in AGA fetuses (P<0.05). Birth weight and gestational age were significantly lower in SGA fetuses than in AGA fetuses (P<0.05). There were no significant differences in baseline rate and acceleration ,maternal age and parity, Apgar score in 1 minute, meconium staining, mode of delivery, NICU admission, between SGA and AGA infants. Small for Gestational Age infants were more frequent in pregnancies with second-trimester decelerations compared with those without second-trimester deceleration (P<0.05). Baseline FHR variability in pregnancies with second-trimester decelerations was significantly higher than in pregnancies without second-trimester deceleration (P<0.05).
Conclusion: Periodic or episodic decelerations and increased FHR variability during late second-trimester EFM were associated with an increased risk of SGA infant
Davari Tanha F, Poor Matrood E, Kaveh M, Yarandi F, Khademi Afsaneh, Hantoosh Zadeh S, Eftekhar Z,
Volume 63, Issue 4 (7-2005)
Abstract
Background: We conducted this study To find relationship between maternal glucose challenge test (GCT) levels and fetal body weight (BW).
Materials and Methods: We analyzed five hundred women with singleton pregnancy, who had GCT at 24-28 week during pregnancy. All of them had no history of hypertension and diabetes mellitus or other medical disease before pregnancy or during previous pregnancy, and all of them had weight gain appropriate with their pre pregnancy body mass index (BMI). Also nobody had history of drug abuse or smoking. In this descriptive–analytic survey, maternal age, gravidity, BMI,GCT level ,gestational age (GA) , sex of neonate, rout of delivery , newborn weight and apgar score were evaluated .The student’s T-test and logistic regression were used for statistical analysis. We used Pearson coefficient and receiver operating characteristic (ROC) curve and chi-square test for determination GCT threshold.
Results: We found rate of small for gestational age (SGA) in newborns statistically was significant, who their maternal GCT level was ≤ 80mg/dl, P value: 0/018, specificity 89%, sensitivity 58% and confidence interval: 95% (0/162-0/545).
Conclusion: Low GCT level has association with SGA and can be used as a predictive test and may be an indication for dietary intervention.
Borna H, Borna S, Rafati Sh, Haji Ebrahim Tehrani F,
Volume 64, Issue 8 (8-2006)
Abstract
Background: A variable hematological value without clinical sign of sepsis or hematological disorder is often observed in newborns. The purpose of this study was to investigate hematological measurements in umbilical cord vein of newborns delivered spontaneously or by cesarean section.
Methods: We studied 150 pregnant women who delivered term normal infants. The patients were divided into two groups according to the route of delivery: vaginal (n=75) and cesarean section (n=75). Immediately after delivery, umbilical cord blood samples were collected. Any possible relationship between mode of delivery, gestational age, gravidity, parity, sex, weight of the new born infant, and the duration of different phase of labor with the hematological parameters was investigated.
Results: We observed a significant increase in all hematologic parameters including hemoglobin and hematocrit levels and WBC, platelet and RBC counts in newborns delivered spontaneously (p<0.001). The lymphocyte counts were similar in two groups. Male infants and newborns with higher gestational age showed a higher hemoglobin and hematocrit levels. Increased parity and gravidity correlated with a decrease in all hematological values of umbilical vein blood except of lymphocyte count (p<0.001). Prolonged duration of first and second stage was associated with higher mean leukocyte, neutrophil, platelet, hemoglobin and hematocrit values.
Conclusion: The mode of delivery, gestational age, parity, gravidity, sex and weight of newborn, and the duration of first and second stage of labor can influence on hematological parameters of umbilical cord blood.
Borna S, Haghollahi F, Golestan B, Norouzi M, Hanachi P, Shariat M, Sarafnejad A, Niroomanesh Sh,
Volume 67, Issue 5 (8-2009)
Abstract
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Background: Zinc
is one of the elements necessary for growth and health in human. Some evidences
indicate that zinc deficiency is one of real difficulties for the public health
in both developed and developing countries. Since the pregnant women are more at
risk of zinc deficiency, the objective of this study was to determine the rate
of zinc deficiency in pregnant women in the 3 trimesters and to compare these data
with that of the healthy controls.
Methods: This research was an analytic- descriptive study which
was done on 677 pregnant women in 3 Trimesters and 140 non pregnant groups who referred to clinic of Tehran
University. Blood sample were taken And serum zinc was assessed By Enzymatic
technique.
Results: The prevalence of zinc deficiency is 16% in pregnancy
and 0%
in non pregnant women with a significant difference between two groups (p<0.001). Zinc
deficiency had no relation to mother's age, gestational age, Iron
supplementation, Parity and mothers BMI. Hemoglobin level showed a direct relation to zinc
deficiency and was grossly found to be more prevalent in Hb levels less than 12 (CI: 1/36-4/26, OR=2/4).
Conclusion: Acording to the finding of
presented study, zinc deficiency is more prevalent in Hb<12 inspite of iron
supplementation. Iron and zinc supplements in pregnancy period seem to be more
effective for Hb repair in each case.
Nasrin Niromand , Fereshteh Gharib Pour , Nasrin Moghadami , Farahnaz Sadat Ahmadi , Batool Ghorbani Yekta ,
Volume 71, Issue 5 (8-2013)
Abstract
Background: Recent studies have suggested that impaired fetal growth are indicators that may be present in the first trimester. The aim of this study was to investigate the relationship between crown-rump length (CRL) and pregnancy associated plasma protein-A (PAPP-A) measurements in first trimester for low birth weight (LBW).
Methods: This prospective cohort study were on 120 pregnant women in first pregnan-cy trimester, in Women's Hospital Mirza Kochak Khan in 2011-2012. Gestational age according to crown-rump length and gestational age according to last menstrual period (LMP), neonatal weight, small for gestational age, pregnancy associated plasma protein-A and low birth weight were recorded. Main outcome measures was weight and gestational age at birth. Statistical tests used included descriptive statistics, t-test, χ² and all tests were two-tailed and differences with P<0.05 were considered to be statistically significant.
Results: Our findings showed that a total of 120 cases were included CRL Z-score and log 10 (MOM PAPP-A) were positively correlated with fetal birth weight. The mean Crown-rump length Z-score was significantly can be reduced in LBW in first trimester pregnancy. (P<0.001) Mean PAPP-A in low birth weight was (0.4±0.11 MOM), but in normal weight infants was (1.04±0.7 MOM). (P=0.011) also mean PAPP-A in pregnant women with SGA infants is significantly less than other pregnant women (0.5±0.2 versus 1.1±0.7) (P<0.001).
Conclusion: Our data suggest that crown-rump length and maternal levels of PAPP-A measured during the first trimester are independent factors that influence fetal birth weight. But their predictive powers are not sufficiently good for them to be used alone for low birth weight screening.
