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Showing 6 results for Soft Tissue
A retrospective study of the head & neck sarcoma in Tehran Imam Khomeini Hospital and cancer institute, 1987-96
E Razmpa , M Mohagheghy , P Mansoory ,
Volume 57, Issue 3 (6-1999)
Abstract
Approximately 15% of sogt-tissue sarcomas occur in head neck area and sarcma should be considered in the differential diagnosis of any tumor mass in this anatomic region, especially in younger patient. This was a retrospective study that reviewed all head and neck sarcoma cases registered at Imam Khomeini Hospital and Cancer Institute during the period 1987-1996. Using medical records, relevant informations including demographic, medical and risk factors were collected. Analysis of data on 40 eligible cases revealed, age range of 31-40, yearsmale sex and residence in cities as risk factors. Osteosarcoma was the most frequent pathology and painless mass was the most frequent sign in all histologic subtypes. In 80% of cases the tumors were primary and in 42.5% the disease recurred after treatment.
Evaluation of mortality and length of therapy in patients with soft tissue infections 1989-99
Geranmayeh L, Alipoor S,
Volume 60, Issue 2 (5-2002)
Abstract

Background: Necrotizing soft tissue infections are one of the most dreaded infections in human and result in a very high rate of mortality. The treatment of these infections must be very aggressive and consists of radical debridement of all necrotic tissue accompanied by appropriate antibiotics.

Materials and Methods: This study was undertaken to assess the mortality rate, the time from diagnosis to cure, and some of the parameters which may affect mortality in our patients. In this descriptive, retrospective study first files from patients attended by necrotizing soft tissue infections including Fournier's gangrene or disease, gas gangrene, hemolytic streptococcal infections, myonecrosis, necrotizing fascitis and related subjects in Sina and Amir-Alam hospitals from 1989 to 1999 were studied. Data were extracted and analyzed by SPSS.

Results: The total number of cases was 36. The median age was 47.69 years. Seven of the patients were female. The median time from onset to cure was 10 days. The most common site affected was the perineum and the most common etiology was perianal abscess. Diabetes mellitus was the underlying disease mostly observed. Half of the patients had received inappropriate treatments. In this group mortality was higher.

Conclusion: It is crucial that general practitioners be acquainted with the diagnosis of necrotizing soft tissue infections so that patients are referred immediately to surgical centers. In our referral center the mortality was acceptable but it can be lowered further. The sex, sites of infection, underlying disease and etiologies in our patients were similar to patient in other countries except for alcoholism. It appears that data in foreign texts can be attributed to Iranian patients.


Inguinal hernia as a manifestation of epithelioid sarcoma: a case report
Jalali Sa, Motabar Ar,
Volume 66, Issue 9 (12-2008)
Abstract

Background: Epithelioid sarcoma is a malignant soft tissue tumor of uncertain histogenesis, categorized as a morphologically distinct neoplasm that characteristically affects the distal parts of the extremities in young adults. In fact, epithelioid sarcoma is the most common soft tissue sarcoma in the hand and wrist.

Case report: This 32 year-old male presented with an inguinal swelling, for which he underwent surgery with the initial intent of inguinal hernia repair. With this uncommon manifestation and site, among the differential diagnosis were abscess and GI malignancies. However, after a supplementary evaluation that included biopsy of the ulcer margin, the diagnosis focused on undifferentiated high-grade epithelial tumor, highly suggestive of epithelioid sarcoma. Immunohistochemical studies revealed CD34 and cytokeratin positivity, which confirmed this diagnosis.

Conclusion: Due to the malignant nature, invasive behavior and high recurrence rate of this tumor, as well as its unknown response to chemotherapy and radiation, extensive resection and hepatectomy are recommended for treatment.


Soft tissue chondroma: a case report
Haeri H, Shariat Torbaghan Sh, Nili Ahmadabadi F,
Volume 69, Issue 1 (4-2011)
Abstract
Background: Soft tissue chondroma is a rare slow-growing benign cartilage forming tumor. Tumors of this kind arise from the relative mesenchymal tissue and have tendency to occur in the fingers and toes. Due to its rarity, this tumor is likely to go undiagnosed. Histopathological examination usually reveals the correct diagnosis. Case presentation: Hereby, we report a case of soft tissue chondroma in a 27 year-old woman presented with a slow-growing mass in the volar aspect of her right hand. The tumor had developed over a 7-month period. The skeletal system was unremarkable on X-ray evaluation. The lesion was excised and the histopathological findings revealed a well-delineated cartilaginous neoplasm with lobular pattern. The tumor was composed of mature chondrocytes without atypia and the findings were compatible with chondroma. Conclusion: There are various hypotheses about the etiology of soft tissue chondromas and their microscopic findings are variable. They have a good prognosis. Recurrence is rare and malignant transformation has not been reported yet.
Primary paravertebral hydatid cyst: a case report
Gh Maddah, H Shabahang, R Razaei, B Gohari,
Volume 71, Issue 2 (5-2013)
Abstract

Background: Eating the egg of Echinococcus granulosus tapeworm in vegetables contaminated with dog's fecal material is the main cause of hydatid cyst. The most common involved organ is liver and the second are lungs. Spinal involvement especially primary involvement of paravertebral soft tissue without vertebral and extradural involvement is very rare. We report a case with paravertebral hydatid cyst without vertebral involvement.
Case presentation: A 61 years old man patient resident of Torbatjam, Khorasan Razavi provience, was admitted to our department complaining a mass in back from six years ago. In physical examination he had several right paravertebral masses. MRI reveals a huge multilocular mass in the right paraspinal from T1 to L5 that is accompanied by ribs erosion without destruction. Operation was performed and the cyst was completely removed while contained several liquid-filled cysts, the hydatid-like cysts. Pathological findings were confirmed the diagnosis. Albendazole (10mg/kg) was prescribed post-operatively for six months. Recurrence has not occurred after two years follow up.
Conclusion: Hydatid disease is a major infectious disease that is a main problem in many countries. In some articles paravertebral involvement without vertebral and extradural involvement is reported but primary paravertebral involvement with hydatid cyst is very rare. In this case we report paravertebral without vertebral involvement and the patient did not show any sign of spinal and vertebral pressure. In spite of the fact that hydatid cyst involves liver and lungs more than other organs, it can involve any organ and this point should be taken into consideration especially in the endemic areas.


Cutaneous granular cell tumor: case report
Mahdi Ghoncheh, Narges Nazeri ,
Volume 78, Issue 10 (1-2021)
Abstract
Background: Granular cell tumor (Abrikossoff’s tumor) is a rare and slow-growing tumor of the soft tissue. Originated from the Schwann cells, it is often a benign tumor, but it can be malignant in 1-3% of the cases. Malignant cases can cause significant morbidity and mortality. It may develop in many anatomic locations, especially in the head and neck region, and also in skin and subcutaneous tissue.
Case Presentation: The patient was a 27 years old female who was referred to the Imam-Reza Hospital of Birjand because of a subcutaneous mass in the left inguinal region. The tumor was appeared six months ago as a painless slow-growing nodule. In physical examination, there was a 3×4 cm subcutaneous tumor in the left inguinal region. The tumor was attached to the skin but not to the deep and surrounding tissues. There was not any evidence of lymphadenopathy or distant metastasis.  The patient was admitted in September 2017. The tumor was excised surgically with a one cm safe margin. The post-operative course was uneventful. In histopathology examination, there was a non-encapsulated neoplasm containing polygonal cells with round to oval nuclei and abundant fine pas-positive granules in the eosinophilic cytoplasm. There were fibrous bands between the tumoral cells. Overlying epithelium shows foci of pseudoepitheliomatous hyperplasia. This finding was compatible with granular cell tumor. Immunohistochemistry (IHC) staining of the cytoplasm and the nucleus for s-100 protein and cytoplasm for CD68 was also positive. The patient is symptom-free and without any sign of local recurrence or distant metastasis for 1.5 years post-operation.
Conclusion: Although it’s a rare tumor, the granular cell tumor must be considered in the differential diagnosis of soft tissue tumors. Surgical excision with a safe margin is the treatment of choice for the tumor. It is recommended that the patients must be observed for two years postoperatively.

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