Volume 23, Issue 4 (winter 2018)
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Yeganeh M R, Gholami S, Tabari R, Atrkar Roshan Z, Rimaz S, pouralizadeh M. The effect of controlled sedation based on the Richmond scale on the duration of mechanical ventilation and the changes of blood pressure in patients following coronary artery bypass graft surgery: A randomized clinical trial
. Journal of Hayat 2018; 23 (4) :372-386
URL: http://hayat.tums.ac.ir/article-1-1937-en.html
URL: http://hayat.tums.ac.ir/article-1-1937-en.html
Mohammad Reza Yeganeh1 
, Somayeh Gholami1 , Rasoul Tabari1 , Zahra Atrkar Roshan2 , Siamak Rimaz3 , Moluk Pouralizadeh * 4
, Somayeh Gholami1 , Rasoul Tabari1 , Zahra Atrkar Roshan2 , Siamak Rimaz3 , Moluk Pouralizadeh * 4
1- Dept. of Nursing, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran
2- Dept. of Statistics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
3- Dept. of Anesthesiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
4- Dept. of Nursing, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran ,pouralizadehm@gmail.com
2- Dept. of Statistics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
3- Dept. of Anesthesiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
4- Dept. of Nursing, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran ,
Abstract: (5650 Views)
Background & Aim: Sedation after coronary artery bypass graft surgery can prevent the side effects of the treatment. The purpose of this study was to determine the effect of controlled sedation based on the Richmond scale on the duration of mechanical ventilation and the changes of blood pressure in patients following coronary artery bypass graft surgery.
Methods & Materials: In a single blind randomized clinical trial (IRCT2017050517693N2) from June to August 2017, a convenience sample of 80 patients after coronary artery bypass graft surgery, hospitalized in the intensive care unit of Heshamat Center, Rasht, were selected and randomly allocated into two groups (each group=40). Sedative drug dose was determined using the Richmond agitation sedation scale in the intervention group and determined routinely (based on hemodynamic changes) in the control group. Pain as a confounding variable was evaluated using CPOT tool. Data were analyzed by descriptive statistics and Chi-square, Mann-Whitney, independent t-test and repeated measures ANOVA using the SPSS software version 22.
Results: The mean age of samples was 59.89±7.53 and 66.7% of them were male. There was a significant difference between two groups in the duration of mechanical ventilation (P<0.04), the changes of patients’ blood pressure (P<0.05), need for a vasopressor drug (P<0.05) until extubation and need for the first administration of sedatives (P<0.001).
Conclusion: Utilizing the Richmond tool can reduce the patient’s dependence on ventilator and changes in arterial pressure. Also, using this tool can prevent unnecessary and early administration of sedative and vasopressor drugs in patients.
Methods & Materials: In a single blind randomized clinical trial (IRCT2017050517693N2) from June to August 2017, a convenience sample of 80 patients after coronary artery bypass graft surgery, hospitalized in the intensive care unit of Heshamat Center, Rasht, were selected and randomly allocated into two groups (each group=40). Sedative drug dose was determined using the Richmond agitation sedation scale in the intervention group and determined routinely (based on hemodynamic changes) in the control group. Pain as a confounding variable was evaluated using CPOT tool. Data were analyzed by descriptive statistics and Chi-square, Mann-Whitney, independent t-test and repeated measures ANOVA using the SPSS software version 22.
Results: The mean age of samples was 59.89±7.53 and 66.7% of them were male. There was a significant difference between two groups in the duration of mechanical ventilation (P<0.04), the changes of patients’ blood pressure (P<0.05), need for a vasopressor drug (P<0.05) until extubation and need for the first administration of sedatives (P<0.001).
Conclusion: Utilizing the Richmond tool can reduce the patient’s dependence on ventilator and changes in arterial pressure. Also, using this tool can prevent unnecessary and early administration of sedative and vasopressor drugs in patients.
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