Volume 24, Issue 4 (10-2024)
ijdld 2024, 24(4): 210-221 |
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Madanipour S, Sadeghi A, Purrazi H. The Effect of Eight Weeks of High Intensity Interval Training (HIIT) and L -Carnitine Consumption on the Expression of BMP7 Protein in Visceral Adipose Tissue in Male Wistar Diabetic Rats. ijdld 2024; 24 (4) :210-221
URL: http://ijdld.tums.ac.ir/article-1-6311-en.html
URL: http://ijdld.tums.ac.ir/article-1-6311-en.html
1- Department of Sport Sciences, Imam Khomeini International University, Qazvin, Iran
2- Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran ,dr.sadeghi85@gmail.com
3- Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran
2- Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran ,
3- Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran
Abstract: (516 Views)
Background: Adipogenesis is a dynamic process that leads to the phenotype of mature fat cells and plays a significant role in obesity and diabetes. The present study investigates the effect of Eight –Weeks of High-Intensity Interval Training (HIIT) and L -carnitine Consumption on the expression of BMP7 protein in visceral adipose tissue in diabetic rats.
Methods: In an experimental clinical-intervention study, 50 male Wistar rats were divided into 5 equal groups of control (C), diabetic (D), supplemental diabetic (D + LC), diabetic with exercise (D + T), supplement and exercise (D + LC + T). The training program consisted of eight weeks, 5 sessions per week (6 to 12 2-minute sessions with an intensity of 85-90% of the maximum speed). The subjects received 30 mg/kg body weight L-carnitine through drinking water. Visceral fat was extracted and the expression level of BMP7 protein was assessed using Western Blotting. Data analysis was performed by one-way ANOVA and Tukey post hoc test at a significant level of (P< 0.05).
Results: The results showed that the expression of BMP7, the adipogenesis stimulating protein, in (D + T) and (D + LC + T) groups increased significantly (P< 0.001).
Conclusion: According to the results, it seems that HIIT exercise alone and with L-carnitine Consumption is more effective in the expression of protein associated with adipogenesis expression in visceral fat. However, a clear statement requires further research in this area.
Methods: In an experimental clinical-intervention study, 50 male Wistar rats were divided into 5 equal groups of control (C), diabetic (D), supplemental diabetic (D + LC), diabetic with exercise (D + T), supplement and exercise (D + LC + T). The training program consisted of eight weeks, 5 sessions per week (6 to 12 2-minute sessions with an intensity of 85-90% of the maximum speed). The subjects received 30 mg/kg body weight L-carnitine through drinking water. Visceral fat was extracted and the expression level of BMP7 protein was assessed using Western Blotting. Data analysis was performed by one-way ANOVA and Tukey post hoc test at a significant level of (P< 0.05).
Results: The results showed that the expression of BMP7, the adipogenesis stimulating protein, in (D + T) and (D + LC + T) groups increased significantly (P< 0.001).
Conclusion: According to the results, it seems that HIIT exercise alone and with L-carnitine Consumption is more effective in the expression of protein associated with adipogenesis expression in visceral fat. However, a clear statement requires further research in this area.
Type of Study: Research |
Subject:
Special
Received: 2023/12/3 | Accepted: 2024/03/10 | Published: 2024/10/31
Received: 2023/12/3 | Accepted: 2024/03/10 | Published: 2024/10/31
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