Skin moisturizers

Malakooti, Shiva; Ahmad Nasrollahi, Saman; Firooz, Alireza

Volume 6, Issue 1 (Volume 6, Number 1 2015) jdc 2015, 6(1): 46-57 | Back to browse issues page

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Malakooti S, Ahmad Nasrollahi S, Firooz A. Skin moisturizers. jdc 2015; 6 (1) :46-57
URL: http://jdc.tums.ac.ir/article-1-5111-en.html

Skin moisturizers

Shiva Malakooti¹

, Saman Ahmad Nasrollahi ^*

², Alireza Firooz³

1- Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
2- Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran , snasrollahi@tums.ac.ir
3- Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

Abstract: (6941 Views)

The function of the horny layer of the skin as a barrier is to protect the underlying tissues from infection, dryness, and mechanical stress. Disruption of this function results in increased transepidermal water loss (TEWL) and is associated with conditions like atopic dermatitis and other chronic skin diseases. Moisturizers have been shown to improve these conditions through restoration of the integrity of the stratum corneum, acting as a barrier to water loss and replacement of skin lipids and other compounds. Also, moisturizers are commonly used to reduce fine lines and make the skin appear smooth and soft. They contain varying combinations of emollients, occlusives, and humectants to achieve their beneficial effects, and there are an overwhelming number of formulations available.

Keywords: skin barrier, emollient, humectant, moisturizer, occlusive

Full-Text [PDF 420 kb] (16263 Downloads)

Type of Study: Review | Subject: Special
Received: 2015/06/21 | Accepted: 2015/06/21 | Published: 2015/06/21