This study is for appointment the dose of systemic 4 groups of patients selected for this study.First group had sealling, root planing and planing and periodontal surgery and no drugs. Second group had sealling, root planing and periodontal surgery with 1 gr per day of tetracycline for two weeks and third group for 3 weeks and fourth group for 4 weeks.The fourth group was.the best clinical improvement. The indexes were PPD, CAL, PI, GI.
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