Journal of Dental Medicine

Mendeley  

Zotero  

arian R, namazi, nojedehian H, najafi F, yadegari Z, karbaschi R, et al . The effect of adding fluorinated graphene nanoparticles on fluoride release in a commercial fissure sealant: an in vitro study. jdm 2024; 37 : 1
URL: http://jdm.tums.ac.ir/article-1-6245-en.html

Background and Aims: Using fissure sealant is one of the most effective methods of preventing pit and fissure decay. Fluoride has been added to various materials as a known anti-caries agent. Fluorinated graphene (FG) has gained attention due to its unique properties. The specific structural characteristics of graphene fillers, besides having antibacterial properties by increasing the rate of fluoride release and charge and neutralizing the acidic pH of the environment, is a suitable option in many treatments. This study investigated the effect of addition of fluorinated graphene nanoparticles on the fluoride release in Fissurit®, a commercial fissure sealant.
Materials and Methods: In this in vitro study, fluorinated graphene oxide (FGO) with bright white color was prepared. After synthesis, 0, 1, 2 and 4 by weight percent were added to the fissure sealant (Fissurit®). Then, the release of fluoride in this material was measured and compared with the commercial fissure sealant containing fluoride (Fissurit®).
Results: According to the obtained results, the amount of fluoride released from groups with different percentages of FGO had a direct relationship with the percentage of FGO addition. Also, at different times, there was a significant difference between the groups with FGO and the control group without FGO (P<0.001).
Conclusion: Addition of FGO to the fluorinated fissure sealant caused the release of fluoride and the possibility of recharging it. The power of releasing fluoride and its recharging in fissure sealant with FGO was higher than the fluorinated fissure sealant, but its fluoride was discharged at a faster rate.