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Showing 6 results for GHorbani

H Nahrevanian , M Assmar , S. M Ghorbani ,
Volume 3, Issue 2 (3 2005)
Abstract

Cryptosporidiosis is a parasitic zoonosis prevalent all over the world and recognized as one of the important causes of diarrhea in children and immunodeficient subjects. The manifestations range from self-limited acute diarrhea in immunocompetent individuals to fatal chronic diarrhea in immunocompromised patients. In this study, conducted in Greater Tehran, 214 patients in 7 disease categories in 10 hospitals were investigated. Samples were collected from both patients with immune deficiency symptoms (Test group) and those with an intact immune system (Control group). Overall, 22.4% of patients had diarrhea and 77.6% had stools with a normal consistency. 1.4% of immunocompromised patients and 6.3% of those with diarrhea were found to harbor Cryptosporidium infections. These Cryptosporidium-positive cases included one patient with AML and two AIDS patients. The incidence rate of infection in AML and AIDS patients who had diarrhea was 11.1% and 33.4%, respectively. While the infection is usually self-limited in immunocompetent subjects, it could be fatal in immunodeficiency states. Therefore attention must be paid to effective disease prevention in immunocompromised subjects.
S.r Majdzadeh, Sh Nedjat, J Gholami, M Ghorbani, S Nejat , M Shokouhi, K Maleki , R Yousefi,
Volume 5, Issue 4 (5 2008)
Abstract

Background and Aim: In the past few years publications in the field of medicine have increased considerably in Iran and knowledge production in this country shows the greatest growth rate in the entire Middle East region. Considering the fact that 12% of all faculty members in the health and medical sector in Iran are employed by Tehran University of Medical Sciences, this university is regarded as the country's leading research institution. This study is focused on the behavior of the researchers in this university in terms of collaboration in research and factors that affect such behavior.

Materials and Methods: Our samples included all research projects in Tehran University of Medical Sciences that had obtained grants from inside and outside the university in 2004, had registered their contracts, had been finished by the time of this study (October 2006- March 2007) and whose final reports had been submitted (315 projects). The data collecting forms were filled for 301 files. The researcher's questionnaire was sent to the principal investigators of the projects and eventually 208 questionnaires were collected. We used the SPSS software package and the usual statistical tests (frequency ratio, chi square, analysis of variance and multiple linear regression with the Enter method) to assess the factors affecting the participation scores of individuals. Based on the data gathered from the forms, we used the UNICET software to analyze the 'cooperation network' between project directors and their principal co-workers and the relationship between different sections of the university.

Results: Only in 2.2 percent of the projects whose contracts were arranged in 1383 there has been some cooperation between the project director/principal coworkers and non-academic organizations. This ratio reaches 2.5% for collaboration with other universities. Among all projects, health system research programs show a better status of collaboration. Linear regression analysis showed that another important factor affecting the participation score is the "method for choosing the research topic". University-affiliated research centers only collaborate with the Schools of Medicine and Public Health, while in the School of Rehabilitation and Physical Medicine all projects are defined within the School's own structure, with virtually no collaboration with any other sections of the university.

Conclusion: The present study showed that research programs in this university include little collaboration with organizations outside the university or with other universities. Part of this is related to the current structure of the research sector in the country, which is largely financed by the government with hardly any participation by the private sector. Current potentials within the University make it possible to embark upon joint research initiatives with other academic institutions. As the possible effect of intervention on health system research has been shown, policies can be implemented to promote effective collaborative research at university and national level.


Esmaeil Ghorbani, Yavar Rassi, Mohammad Reza Abai, Amir Ahmad Akhavan,
Volume 12, Issue 3 (1-2015)
Abstract

 Background and Aim: Sand flies are responsible for transmission of leishmaniasis, papatasi fever and carrion disease. Warning of sand fly population is the first step for the establishment of baseline data for the vector control operations of visceral leishmaniasis (VL). In order to attempt to the difference between species composition and bieocology of sand flies, the comparative research was carried out in west and east of Meshkinshahr district where having high and low prevalence of VL as well as mild semiarid and semiarid steppe climates respectively.

 Materials and Methods : Sand flies were biweekly collected using sticky paper traps from indoor and outdoor shelters from four villages at west and east of Meshkinshahr district. The specimens was removed from sticky paper traps and washed in acetone and preserved in 70% alcohol. The preserved sand flies were mounted using Puri’s media and identified using valid keys. The labeled specimens were deposited in Medical Entomology Museum, School of Public Health under code GC22ST6-93 .

 Results: During this study, totally 783 and 400 sand flies were respectively caught from indoor (19-27%) and outdoor (73-81%) of both at west and east. The sex ratios of collected sand flies were estimated 2.3 and 1.9. in latter areas. The genera percentage of sand flies were 66.3-64.5% for Phlebotomus and 33.7-35.5% for Sergentomyia compromising of 7 subgenera which included in 20 and 17 species respectively in west and east areas. For the first time, Se.sintoni and Se.mervynae was reported in Meshkinshahr district.

 Conclusion: The Ph.kandelakii and Ph.perfiliewi were introduced as prevalent species in the west area compared to the east. In the west area, activity duration and number of generation was higher than east. The prevalent species in the east area was Ph.papatasi. The high density of Ph.anderjevi was seen in both studied areas. The most proven vectors of visceral leishmaniasis were revealed in the west of Meshkinshahr district.


Azadeh Khalilitehrani, Mostafa Ghorbani, Saeed Hosseini, Hamideh Pishva,
Volume 13, Issue 3 (12-2015)
Abstract

Background and Aim: Malfunction in the energy homeostasis central system resulting from melanocortin receptor 4 (MC4R) mutations is considered to be an important factor in development of obesity. Although physical activity can weaken the effect of obesity-related genes, very few investigations have been carried out in relation to the MC4R gene. This study was conducted to investigate the association between physical activity and body mass index (BMI) in different MC4R genotypes (rs17782313).

Materials and Methods: A sample of 400 individuals was randomly selected from among subjects participating in the Iranian Multicenter Osteoporosis Study (IMOS). Their weights and heights were measured and their dietary intakes and physical activity data assessed using validated questionnaires. In addition, the different MC4R genotypes (rs17782313) were determined in the subjects by the PCR-RFLP method. Finally, using the adjusted multiple linear regression model, the probable effect of physical activity on BMI in different MC4R polymorphisms (rs17782313) was determined.

Results: Only in individuals with the CT genotype was a statistically significant association (p<0.05) observed between body mass index and physical activity (hr/d and METs-hr/wk).

Conclusions: Physical activity, particularly in heterozygous MC4R polymorphism individuals (rs17782313), can play an effective role in reducing body mass index.


Shayesteh Khosravi, Amir Mansour Alavi Naeini, Ahmad Reza Dorosti Motlagh, Mostafa Ghorbani, Zahra Shateri,
Volume 13, Issue 3 (12-2015)
Abstract

Background and Aim: Diabetes mellitus is one of the most common medical problems in pregnant women. Nutrition plays an important role in the prevention and control of this disease. Some studies have found a relationship between gestational diabetes mellitus (GDM) and food insecurity. The objective of this study was to investigate the association between food insecurity and GDM.

Material and Methods: : This case-control study included 274 pregnant women (137 GDM cases and 137 healthy controls) selected by convenience sampling. Data on the subjects’ food insecurity, demographic features and physical activity (MET) were collected by interviewing and their heights and weights measured. For the analysis of the data, the Chi-square test, independent sample t-test and multivariate and univariate logistic regression tests were used, the statistical software being SPSS 16.0.

Results: On the whole, 18.2% and 21.9% of the women in the case and control groups suffered from food insecurity, respectively. There were statistically significant differences between the case and control groups with regard to a previous history of pregnancy, a family history of diabetes in the first and second degree relatives, and a history of giving birth to a baby weighing over 4 kgs.

Further analysis of the data showed a family history of diabetes mellitus and a low socio-economic status to be independent risk factors for GDB.

Conclusion: No statistically significant difference was observed between food insecurity of the women and gestational diabetes mellitus in this study. Despite this finding, considering that there are associations between food insecurity and other types of diabetes mellitus, we recommend further studies on this subject to be able to either accept or reject the hypothesis on the association between food insecurity and gestational diabetes mellitus.


Samira Kazemi, Hadis Khoshnavaz, Masoumeh Ghorbanideh, Sakineh Varmazyar, Salman Sheikhi,
Volume 16, Issue 4 (3-2019)
Abstract

Background and Aim: In the household appliances industry, due to doing such work operations as manually moving pieces, there is the probability of occurring musculoskeletal disorders and muscle fatigue. Therefore, this study aimed to investigate muscle fatigue and its relationship with the prevalence of musculoskeletal disorders among personnel of a household appliances factory. Data were collected and analyzed using descriptive statistical and logistic regression tests.
Materials and Methods: This descriptive-analytical and cross-sectional study, including 150 employees of a household appliances factory, was conducted in 2016. Data about the prevalence of musculoskeletal disorders and muscle fatigue were collected using a standard Nordic and muscle fatigue assessment (MFA) questionnaire, respectively, and analyzed using the logistic regression test.
Results: The prevalence of musculoskeletal disorders in the lumbar region, knees and neck was 33.3%, 25.3%, and 21.3%, respectively. In addition, the results of MFA showed that reduction of the risk of muscle fatigue in the shoulders, wrists and arms needs corrective action as a top priority in 28.7%, 28%, and 26.7% of the employees, respectively. Statistical analysis showed no significant relationship between muscle fatigue and the frequency of musculoskeletal disorders.
Conclusion: Considering disorders in the lumbar region and risk of fatigue in the shoulder region, the risk can be reduced by proper corrective actions, such as increasing the height of pallets, using tables with adjustable heights, and layout of the parts in a normal access range.
 

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