K Samimi-Rad, B Shahbaz, M Mahmoodi, M Noroozi, M Fayaz Vaseghi,
Volume 5, Issue 3 (4 2007)
Abstract
Background and Aim: Patients with hemophilia and thalassemia are at high risk for hepatitis C virus (HCV) infections. Unscreened blood and blood products are thought to be the most important risk factors in these two groups.
Materials and Methods: Blood samples were collected from 98 thalassemia patients and 74 hemophiliacs in Markazi province. The presence of anti-HCV antibody was tested by a third generation enzyme immunoassay. All ELISA-reactive samples were tested with the confirmatory third-generation recombinant immunoblot assay RIBA. We used a specially designed questionnaire to obtain data from patients and the software package SPSS 11.5 for statistical analysis.
Results: HCV antibody was detected in 5 thalassemia patients (5.1%) and 31 hemophiliacs (41.9%). Anti-HCV positivity in patients with thalassemia was associated with the total volume of the transfusions, splenectomy, and the duration of treatment. In hemophiliacs, seropositivity was significantly associated with the duration of transfusion treatment (P=0.01) and disease severity (P=0.00). The prevalence of HCV antibody in thalassemia subjects dropped from 8.1% to 0% after the implementation of anti-HCV screening in1996.
Conclusion: In Markazi province, the current policy of screening donors for anti-HCV and the strict safety controls on factor concentrates can effectively protect thalassemia and hemophilia patients from HCV infection.
Mohsen Roshanpajouh, Roksana Mirkazemi, Mehrdad Ehterami, Houman Narenjiha, Hossein Malek Afzali, Hamidreza Sarrami, Majid Rezazadeh, Fatemeh Abbasi, Saeid Noroozi,
Volume 16, Issue 4 (3-2019)
Abstract
Background and Aim: Drug abuse is a long-standing social and public health problem in Iran. Access to accurate, reliable and up-to-date data related to drug use is essential for planning and policy-making for prevention of, treatment of, and harm reduction related to, drug abuse. The purpose of this study was to access accurate data regarding drug abuse prevalence and substance use in Tehran Province population.
Materials and Methods: This study was a cross-sectional household survey with a sample of 6024 individuals aged 15-64 years residing in Tehran Province. Data on demographic characteristics and drug use during the previous week, month and year and the whole lifetime were collected using a researcher-designed questionnaire.
Results: A total of 5646 individuals participated in the study. The lifelong prevalence of cigarette-smoking, hookah-smoking, alcohol consumption and drug use were 21.9%, 26.8%, 12.1% and 7.3%, respectively. The corresponding proportions during the previous week were 12.9%, 10.5%, 1.8% and 2.2%.
Conclusion: The prevalence of cigarette-smoking, hookah-smoking, alcohol consumption and drug use is high in Tehran Province. The prevalence of lifelong cigarette and hookah smoking and alcohol consumption is higher, while that of drug use is lower, than the respective national averages.
