Sm Razavi, S Dabiran, M Panah Khahi, S Asefi, G Zaker Shahrak,
Volume 8, Issue 2 (21 2010)
Abstract
Background and Aim: Nowadays Clinical Skills Centers are important structural components of medical education systems globally. In these centers medical students are trained using a variety of methods and techniques, one method being teaching in structured stations. The objective of this study was to determine the efficacy of this method by comparing the students' self-assessment of their own basic surgical skills before and after structured stations teaching.
Materials and Methods: This quasi-experimental study was conducted in 2004-08 in Tehran University of Medical Sciences. The participants included 268 medical students at the clerkship stage there were 3 trainer groups. The pre- and post-self assessment techniques were used to assess the learning progress. ANOVA & Paired-t and non-parametric tests were used for data analysis.
Results: Irrespective of which year the students were in, self- scoring on 17 cognitive subjects and 10 procedural skills showed a significant improvement after the instruction (p<0.001). There were significant differences among the 3 trainer groups (p<0.001).
Conclusion: This study suggests that teaching basic surgical skills using structured stations is effective in improving practical skills.
Z Zarei Ghane, A Mirshafiey, A.r Razavi, A Sarafnejad, N Aalizadeh, M.r Khorramizadeh,
Volume 8, Issue 2 (21 2010)
Abstract
Background and Aim: Multiple sclerosis (MS) is considered as a common inflammatory disease of the human central nervous system (CNS). 4 amino pyridine (4-AP), a potassium channel blocker, is used widely in MS treatment to reduce fatigue and cachexia often experienced by the patients. The objective of this study was to get a better understanding of the mechanism of action of this drug, using the cell culture model. More specifically, we attempted to determine the effects of the drug on 1. The profileration of, and its cytotoxicity on, the neurons, and 2. The activity of MMP-9 in the neurons.
Materials and Methods: Considering the available reports on the wide range of 4-AP effects, we designed this study to investigate its possible role in proliferation or cytotoxicity of the MS cellular model, i.e. astrocytoma U373-MG, using the MTT assay technique. We also analyzed the effect of 4-AP on cell functionality as assessed by matrix metalloproteinase-9 (MMP-9) zymography.
Results: The results showed that while 4-AP at a concentration of 0.1 and 1 mM has no significant cytotoxic effects on the treated cells, it has remarkable MMP-9 inhibitory effects (p<0.01). The proliferation analyses confirmed the stability of 4-AP effects on cell functionality.
Conclusion: On the whole, the results of the present study show the desirable effect of 4-AP on MMP-9 activity at non-cytotoxic doses, promising its further therapeutic applications.
Behzad Damari, Seyed Hasan Emami Razavi, Ahmad Hajebi, Elham Elahi,
Volume 19, Issue 2 (9-2021)
Abstract
Background and Aim: According to the definition proposed by WHO, social health is a health dimension that impacts, or is affected by, the two physical and mental dimensions. Based on the definition given by the Academy of Medical Sciences of Islamic Republic of Iran, social health includes reciprocal qualitative and quantitative behaviors by individuals towards welfare of the society. Pro-social behaviors and an encouraging environment are considered as the two main components of social health promotion. The purpose of this study was to identify pro-social behaviors in the Iranian society.
Materials and Methods: This was a qualitative study. Data were collected using 1). Literature review based on sources related to Iranian culture and religious advice, as well as published international experiences, and 2). Expert opinions based on focus group discussions on eight specialized disciplines. The data obtained were content analyzed.
Results: Analysis of the data of this study showed twenty pro-social behaviors (possible to be categorized into three domains/areas of social thinking, speech and expression, and behavior):
acceptance of diversity and altruism, understanding human rights, not telling lies, cooperation, humbleness, donation/free contribution, being critical, patience and forgiveness, lack of distrust/suspicion, speaking competence, proper balance/equilibrium, sense of responsibility, brotherhood, personal discipline/order, fidelity, trustworthiness, consultation, cultural exchange, self-identity and, finally, respecting the environment.
Conclusion: Behavior change requires applying evidence-based models, e.g., social marketing. It is, thus, suggested that after investigating and surveying pro-social behaviors in the Iranian society, barriers to pro-social behaviors should be investigated and social marketing programs be developed and implemented aiming to help improve these behaviors.
