Journal of School of Public Health and

Background and Aim: Rabies is one of the oldest and most serious zoonoses in the world. In Iran, the disease has been reported from most of the provinces and among domestic as well as wild animals. This study was conducted in the province of Kerman and aimed to assess the frequency and epidemiological features of suspected and confirmed animal rabies cases from 1993 to 2003.

Material and Methods: During the study period, all cases of suspected animals (brain specimens) had sent to Pasteur institute of Iran for pathological (Negri bodies) examinations. After collecting data on variables such as species of animal, city, season, annual rainfall and temperature, analysis was performed by calculation of Pearson correlation coefficient and Chi square, Fisher's exact, Students's t and Kolmogorov Smirnov tests using the SPSS package (ver.11.5).

Results: From 362 suspected brain samples, 301 (83.1%) had positive serologic and pathological results. We recorded an ascending trend over the study period (p=0.01). The effect of seasonal variations on the frequency of suspected and confirmed cases of animal rabies was significant (p<.001): most cases occurred in winter and fall. The relative frequencies of confirmed cases among the animals were as follows: As for domestic animals, the infection rate in cows was 81.45 % sheep and goats 10.63% dogs and cats, 4 % camels 1.33% and donkeys, 0.7%. Among wild animals (foxes, mongooses, wolves and jackals) the rate was 1.89%. Among wild animals, the total infection rate was 60 %. Concerning the role of predatory animals in the transmission of rabies to domestic animals, among the cases which had been confirmed (28 cases), the predator species were: foxes 50%, wolves 7%, mongooses and jackals 3%. Considering the relationship between frequency of animal rabies  and ecological variations in the province of Kerman, the results of this survey showed that there is some correlation between decreased rainfall (drought) and the resurgence of animal rabies (r=0.34, P=0.001).

Conclusion: The increasing number of stray dogs and the migration of these and wild animals to cities and villages could be an important factor in the spread of rabies in the region. Among various predatory species, the role of foxes in disease transmission merits further investigation.

Background and Aim: Rabies, a viral and zoonotic disease, causes acute and fetal encephalitis in humans and other mammals and is a cause of death in developing countries. It is usually transmitted by animal bite, but other routes of transmission are mucus membranes, breathing, placenta, contaminated instruments, and organ implanting. This study shows the mapping of geographical distribution of animal bite cases, rabies, and death due rabies in 3 Caspian Sea littoral provinces, namely, Golestan, Mazandaran, and Gilan.

Materials and Methods: Data on human and animal rabies cases and animal bites were collected from the Reference Rabies Center of the Pasteur Institute in Tehran and the Rabies Diagnosis Section of the Amol Research Center during 2002-2007.The data was analyzed by the SPSS (11.5) software and mapping was done by Arc GIS 9.2.

Results: During the 6-year period, of the 670,743 animal bite cases reported in Iran 63890 (9.5%) had occurred in Golestan, 25,767 (3.8%) in Mazandaran, and 22,874 (3.4%) in Gilan. The distribution of animal bite cases in the 3 provinces was as follows: Agh ghala, Bandar Torkaman, Azad shahr and Kolaleh in Golestan Galugah, Behshahr, Ramsar and Neka in Mazandaran and Shaft, Masal, Siahkal and Fuman in Gilan. The data also showed that of the total 2,312 animal rabies cases, in Iran, 9.22% had been reported from Golestan, 4% from Mazandaran, and 2.6% from Gilan. Furthermore, animal rabies cases had occurred mostly in Gonbadekavoos, Bandar Torkaman, Gorgan and Kolaleh in the Golestan Province Behshahr, Neka and Chalus in the Mazandaran Province and Masal, Fuman and Rezvanshahr in the Gilan Province. The most important disease vector (91.3%) for both human and animal rabies was the dog. A total of 41 human deaths due to rabies had been reported during the period, 2 being from Mazandaran.

Conclusion: The results show that a more effective disease control and surveillance system is essential and can help improve planning for service provision in the health care centers.