H Eftekhar Ardebilli , S.h Salarilak , H Farokh Eslamlou, K Holakouie Naieni ,
Volume 1, Issue 1 (4-2003)
Abstract
A community-based rubella serological survey of 795 individuals selected by cluster sampling technique from rural areas of Ourmia ,the center of West Azerbaijan province located in the northwestern Iran , was carried out from December 2001 to March 2002. The aims of the study were to characterize rubella epidemiology in a representative non- immunized community in northwest Iran and also to determine national vaccination strategy against rubella. The survey comprised a seroprevalence study, with stratification by age (0-45 years) and sex. Sera from 392 female and 378 male were tested for rubella IgG antibody using enzyme linked immunosorbent assay (ELISA) technique. "Rubella seropositivity" was defined as serum rubella IgG antibody level > or =13 IU/ml. Of the 770 cases, 58.1% were seropositive. Due to mathernal derived antibodies, 100% of the newborns was seropositive. This figure decreased with time until it became zero by 9 months of age. Then from the age of 4y, it began to rise until it peaked at 93.4% in the age group of 15-19 years. Then the seropositivity decreased to 85.7% in the age group of >35 years. Of women in the reproductive age groups (15-45 years), 89.6% were seropositive. No statistically significant difference in seroprevalence was found between the two sexes. This small preliminary study indicates that like many other countries, rubella is endemic in Iran and eliminating rubella and congenital rubella syndrome in the country will require international efforts, including vaccination of preschool- and school-age children and all susceptible young adults.
Arezu Amirali, Ameneh Elikaei, Roxana Mansour Ghanaie, Idesbald Boone, Abdollah Karimi, Tim Eckmanns, Andreas Lutz Jansen, Fatemeh Fallah, Noushin Marhamati, Niloofar Pashaei, Shahriar Janbazi, Ahmad Reza Shamshiri, Hamid Reza Baradaran, Mohammad Hossein Rostami, Masoud Alebouyeh,
Volume 19, Issue 4 (3-2022)
Abstract
Background and Aim: The objective of this study was to determine the seroepidemiological history of SARS-CoV-2 infection among asymptomatic children in Tehran.
Materials and Methods: Blood samples of children younger than 14 years old were collected during the period autumn-winter 2020 and spring 2021 and tested for SARS-CoV-2 IgG antibody using the EUROIMMUN ELISA kit. In addition, questionnaires were used to collect demographic and infection status information in the participants. Data were analyzed using the SPSS software.
Results: Out of the 1142 children collected from the children with no COVID-19 symptoms, 33.3% (381/1142) were found to have had a history of SARS-CoV-2. The positive samples in girls and boys were 34.1% and 33.03%, respectively. Analysis of the data showed no statistically significant differences between the infection rate on the one hand and age, family size, underlying diseases, gender or occupations of the family members on the other hand. In addition, the infection rate was significantly lower in autumn 2020 than in winter 2020 and spring 2021.
Conclusion: SARS-CoV-2 infection can occur in children with no clinical symptoms. In addition, the infection rate is in direct correlation with an increase in age of the children.
