Mehdi Mohebali, Gholamhossein Edrissian, Mohammad Reza Shirzadi, Yavar Hosseingholizadeh, Mohammad Hossein Pashaei, Akbar Ganji, Zabihallah Zarei, Ahmad Kousha, Behnaz Akhoundi, Homa Hajjaran, Hossein Malekafzali,
Volume 9, Issue 2 (11-2011)
Abstract
Background and Aim: Visceral leishmaniasis is a systemic parasitic disease with a high fatality rate in under-5-year-old children. The disease is endemic in some parts of Iran, particularly in the north-west region. In 2001 a visceral leishmaniasis (VL) surveillance system was established for children aged ≤ 12 years in the primary health system in Meshkin-Shahr District, Ardebil Province, situated in the north-west of Islamic Republic of Iran.
Materials and Methods: All cases with clinical signs and symptoms of VL and confirmed positive by the direct agglutination test (DAT) were referred for physical examination and treatment.
Results: The mean annual incidence of VL decreased significantly from 1.88 per 1000 children before (1985-2000), to 0.77 per 1000 child population after (2001-07), the intervention. In the control area with no surveillance, it increased from 0.11 to 0.23 per 1000.
Conclusion: Early detection of VL using serological tests and timely treatment of cases can decrease the mortality and morbidity rates of VL in endemic areas.
