Showing 7 results for Screening
K Samimi-Rad, B Shahbaz, M Mahmoodi, M Noroozi, M Fayaz Vaseghi,
Volume 5, Issue 3 (5-2007)
Abstract
Background and Aim: Patients with hemophilia and thalassemia are at high risk for hepatitis C virus (HCV) infections. Unscreened blood and blood products are thought to be the most important risk factors in these two groups.
Materials and Methods: Blood samples were collected from 98 thalassemia patients and 74 hemophiliacs in Markazi province. The presence of anti-HCV antibody was tested by a third generation enzyme immunoassay. All ELISA-reactive samples were tested with the confirmatory third-generation recombinant immunoblot assay RIBA. We used a specially designed questionnaire to obtain data from patients and the software package SPSS 11.5 for statistical analysis.
Results: HCV antibody was detected in 5 thalassemia patients (5.1%) and 31 hemophiliacs (41.9%). Anti-HCV positivity in patients with thalassemia was associated with the total volume of the transfusions, splenectomy, and the duration of treatment. In hemophiliacs, seropositivity was significantly associated with the duration of transfusion treatment (P=0.01) and disease severity (P=0.00). The prevalence of HCV antibody in thalassemia subjects dropped from 8.1% to 0% after the implementation of anti-HCV screening in1996.
Conclusion: In Markazi province, the current policy of screening donors for anti-HCV and the strict safety controls on factor concentrates can effectively protect thalassemia and hemophilia patients from HCV infection.
M.h Forouzanfar, M Karami, A Fotouhi, R Majdzadeh, P Jamali,
Volume 6, Issue 3 (2-2009)
Abstract
Background and Aim: Amblyopia is an important cause of weak vision and blindness. A preliminary study on validity of the current screening program in Shahrood City's kindergartens showed that this method may not be efficient enough, especially because of low sensitivity and referral problems. We tried to compare efficiencies and costs of screening by trained staff and optometrists in detecting patients.
Materials and Methods: We conducted a cost-effectiveness analysis using the decision-tree method. We replaced nurses with optometrists to compare costs per detected case by the two screening methods. The number of detected cases and costs per each detected case are compared. Also, the cost-effectiveness of four criteria screening examinations (with different validities) used by optometrists was estimated.
Results: Costs per case detected by optometrists and by current screening methods were 270000 and 556000 Rails (Rs), respectively (with baseline examination criteria and 6.4% prevalence). With a lower prevalence of amblyopic patients, CER (cost-effectiveness ratio) will increase in both methods, but the increase in the current screening method is less than the optometric method. In the optometrist method, avoidable costs and savings per detected case vary from 250000 Rs at a prevalence of 7.4% to 1185000 Rs at a prevalence of 1.4%. Sensitivity analysis showed that costs of "monitoring of screening" in the optometrists method and costs of "follow up in the current screening method" have strong effects on CER CER will decrease by 9.6% and 15%, respectively, if this costs decrease to 25%.
Conclusion: The cost, per detected case, of screening amblyopia by optometrists in kindergartens is half that by the current method. In areas with a low prevalence, the efficiency of screening by using optometrists increases remarkably.
Zohreh Keshavarz, Masoumeh Simbar, Ali Ramezankhani, Hamid Alavi Majd,
Volume 9, Issue 3 (3-2012)
Abstract
Background and Aim: Breast and cervical cancer screening is considered a health promotion behavior, influenced by complex factors. The theory of planned behavior provides a useful framework for predicting and understanding the health behavior and designing appropriate educational interventions. Integrating this theory with self-efficacy will increase its predictive value. The objective of this qualitative research project was to understand the factors influencing the behavior of breast and cervical cancer screening of female-workers as a base for future educational planning.
Materials and Methods: This was a qualitative approach research based on the Integrated Model of Planned Behavior and Self-Efficacy. Seventy 20-45 year-old women working in industrial plants in Abbasabad, Pakdasht, selected by purposeful sampling with maximum diversity participated, in 10 groups of 7 each, in focus-group discussions, in which they discussed their experience regarding factors influencing the behavior of breast and cervical cancer screening. Data were collected and their validity, conformability, transferability and dependability confirmed. For data analysis the conventional method of content analysis was used.
Results: The female workers had a low knowledge and attitude concerning the behavior of breast and cervical cancer screening. Attaching importance to comments given by the family members, especially the husband, and preference of treatment to prevention of disease in the society at large were the subjective norms of the female workers. The most important barriers to participating in screening programs were lack of knowledge, depression, fatigue, embarrassment and fear of examinations, fear of being sick, poor quality of services and lack of attention to privacy in health centers, limited access to health centers, and costs of tests. The female workers had a low self-efficacy for planning and overcoming barriers. Most of them had not had screening tests and had no intention of doing their screening tests in the following three month.
Conclusion: The following measures are recommended: designing and implementing specific educational programs in workplaces for female-workers aiming at increasing their awareness and positive attitudes towards breast and cervical cancer screening designing and implementing educational/training programs for families, employers and planners to increase their knowledge and attitude and facilitating women's access to health centers in industrial estates.
Farzaneh Valizadeh, Aziz Allah Batebi, Abolghasem Pourreza, Azadeh Deylami,
Volume 14, Issue 2 (9-2016)
Abstract
Background and Aim: Thalassemia major (ThM) is one of the most common autosomal recessive genetic disorders in the world. Its prevention and control is a priority in the disease prevention programs in the Iranian health system. The ThM screening program (screening at the time of marriage) has been an important step in its prevention in Iran. This study aimed to evaluate this program.
Materials and Methods: This was a descriptive-analytical study in Babosar District consisting of two phases. The first phase was a retrospective descriptive study aiming at finding the background causes of the diseases in subjects under 18 years old (born after March 1997). In phase 2, then, in an interventional analytical study, screening was repeated along with laboratory tests before, or at the beginning of, pregnancy (n = 5500).
Results: Phase 1(cross-sectional descriptive): There were 25 cases of ThM under 18 years old, parents of 15 of whom (60%) had married before 1997 and 4 (16%) had children suffering from ThM (S2). The parents of the remaining 10 (40%) had married after 1997 (S1). Phase 2: Considering the findings of Phase1, an interventional program called thalassemia screening was started in September 2006 including 9750 pregnant or pre-pregnanct mothers. The program led to identifying 20 new beta-thalassemia-carrier couples, including 10 couples married before 1997 and 10 married after 1997 (without official marriage registration, laboratory errors and hemoglobinopathies). All the 20 couples were quickly referred to the Genetic Center, which resulted in prevention of the birth of 4 ThM neonates.
Conclusion: The 9-year intervention (2006-2015) resulted in timely action, preventing birth of 4 thalassemia major babies. Considering incidence of the disease during the previous 9 years (1997-2006), it can be concluded that the before-after randomized clinical trial is an effective way to reduce thalassemia major incidence.
Effat Merghati Khoei, Narges Hoseini Nia, Nasim Abolghasemi, Sanaz Ommaty, Fereshteh Golshani, Alireza Bayat,
Volume 14, Issue 3 (12-2016)
Abstract
Background and Aim: Substance abuse and risky sexual behaviors are intermingled. Both subjects, however, are highly sensitive issues culturally in some societies such as Iran, making assessment of sexual behaviors difficult and challenging. It is particularly difficult to assess and study risky sexual behaviors in the drug-using population. Thus, it seems essential to develop and validate a comprehensive native instrument specific for the Iranian drug-using population to screen their risky sexual behaviors and in treatment settings.
Materials and Methods: A thorough literature review was made to find a tool utilized in addiction treatment settings. The Sex and Drug History Form (SDHF) was translated into Persian. Clients (n = 107) referred to the sexual health clinic in the Iranian National Center for Addiction Studies (INCAS) were selected randomly. Questionnaires were completed through face-to-face interviews by trained research assistants. Data analysis was done using the Cronbach`s alpha and exploratory factor analysis.
Results: Cronbach`s alpha was found to be 0.78. Using the principal component analysis, the Sex and Drug Screening Scale (SDSS) revealed 78.6 of the total variance in two main domains, namely, drug-use behaviors and sexual behaviors. The number of subscales in the original instrument, which was 3, increased to 6.
Conclusion: Substance abuse and addiction significantly affect one's sexual behaviors and safety. The Sex and Drug Screening Scale will enable health workers and therapists to assess the patients' sexual health and risky behaviors at admission, which will facilitate planning, implementing and evaluating intervention programs aiming at treating addiction.
Alireza Heidari, Mohammad Arab, Kourosh Etemad, Behzad Damari, Mansoureh Lotfi,
Volume 16, Issue 2 (9-2018)
Abstract
Background and Aim: The purpose of phenylketonuria (PKU) screening is to assess the risk of, and prevent, the disease in the newborns likely inflicted with it. The aim of this study was to investigate why and how PKU screening was decided to be included in the national health agenda, initiated and implemented in Iran.
Materials and Methods: This qualitative study was conducted based on the Kingdon’s framework model in 2015. The participants were thirty-eight policy-makers, managers and researchers selected by purposeful sampling.Data were collected using semi-structured interviews and analyzed using framework analysis.
Results: The physical and mental disabilities, medical and maintenance costs and the need for rehabilitation services were examples of the problem stream. In addition, sampling based on the National Congenital Hypothyroidism Program and implementation feasibility at the national level were examples of the policy stream. Finally, pressure by the patients' families, the Scientific Children Association and executive managers were examples of the political will stream. When the three streams occurred simultaneously, health policy-makers agreed to implement the program and then was opened the window of opportunity.
Conclusion: Successful implementation of the National Phenylketonuria Screening Program in Iran has been the result of interactions among three streams, namely, nature of the problem, political will and optimal use of policy-makers of the window of opportunity opened.
Sahar Peikani, Naser Nasiri, Halimeh Yaghoobi, Dayoush Bastam, Fatemeh Doost Mohammadi, Mohammad Vahedian Shahroudi,
Volume 16, Issue 4 (3-2019)
Abstract
Background and Aim: Congenital hypothyroidism is the most common metabolic disease and endocrine disorder in children and a major cause of mental retardation, which can be prevented only through early diagnosis and treatment. This study aimed to determine the prevalence of congenital hypothyroidism in newborns referred to Shahid-Ghodsi Health Center in Mashhad, Iran.
Materials and Methods: This cross-sectional study, including 4484 newborns referred to Shahid-Ghodsi Health Center for congenital hypothyroidism screening, was conducted during the first six months of 2015. Data were collected from the screening forms and analyzed using the statistical software SPSS 21, the tests being the two-sample T-test, analysis of variance, Chi-square and Fisher's exact tests; in all the tests the significance level was 5%.
Results: Of the 4484 neonates screened, 51% and 48% were males and females, respectively. The recall rate was estimated to be 2.6% and prevalence of the disease 1 in 370 neonates. There were statistically significant associations between hypothyroidism on the one hand and birthweight, type of feeding (nutrition), primary and serum TSH levels of the neonate on the other.
Conclusion: Based on the findings, the prevalence of congenital hypothyroidism in Mashhad is significantly higher than that national and global averages. It is essential to conduct more comprehensive research to determine the associated factors and design suitable interventions in order to prevent the disease.
