Comparison of ELISA and histopathologic and bacteriologic findings in diagnosis of helicobacter pylori in gastro-intestinal disorders

Mirsalehian , A; Ebrahimi Daryani , N; Sarrafnejad , A; Rastegarian , H

Volume 56, Issue 3 (1 1998) Tehran Univ Med J 1998, 56(3): 16-21 | Back to browse issues page

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Mirsalehian A, Ebrahimi Daryani N, Sarrafnejad A, Rastegarian H. Comparison of ELISA and histopathologic and bacteriologic findings in diagnosis of helicobacter pylori in gastro-intestinal disorders. Tehran Univ Med J 1998; 56 (3) :16-21
URL: http://tumj.tums.ac.ir/article-1-1551-en.html

Comparison of ELISA and histopathologic and bacteriologic findings in diagnosis of helicobacter pylori in gastro-intestinal disorders

A Mirsalehian ^*

, N Ebrahimi Daryani

, A Sarrafnejad

, H Rastegarian

Abstract: (7418 Views)

Helicobacter pylori (H.Pylori) is the most common human infection in the world. This agent has a strong role in pathogenesis of chronic gastritis and peptic ulcer. Therefore introducing of simple and cost effective tests are important for diagnosis of H.Pylori infections. ELISA has been considered as an alternative test compare with biopsy, histological staining, culture and urease test in diagnosis of H.Pylori infection. In this investigation, 111 patients referred to GI endoscopy department of Imam Khomeini Hospitals for U.G.I problems which were evaluated for H.Pylori infection. Culture and histological staining (GIMSA and H & E) were used as a gold standard test compare with ELISA-IgG and urease test. Sensitivity and specificity for ELISA were 90%, 93% respectively. This report suggests that ELISA is a cost effect and valid test in diagnosis of H.Pylori infection

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